First-Lansoprazole
First-Lansoprazole
What is First-Lansoprazole?
First-Lansoprazole is a prescription oral liquid formulation of lansoprazole used to treat acid-related digestive conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, stomach ulcers, and excessive stomach acid production. As a proton pump inhibitor (PPI), it helps reduce stomach acid and relieve symptoms such as heartburn, acid reflux, and indigestion. Learn about First-Lansoprazole uses, dosage, side effects, and acid reflux treatment options.
Side Effects
- Unusual bleeding, bruising, tiredness, or weakness
- Fever, swelling in your body, unusual weight gain, change in how much or how often you urinate, blood in the urine
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, osteoporosis, vitamin B12 deficiency, or phenylketonuria (PKU).
- This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach)Increased risk for heart problems (including heart valve thickening) in children younger than 1 year of age
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Prescription savings · · · ·
What is First-Lansoprazole ?
First-Lansoprazole is a prescription oral liquid formulation of lansoprazole used to treat acid-related digestive conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, stomach ulcers, and excessive stomach acid production. As a proton pump inhibitor (PPI), it helps reduce stomach acid and relieve symptoms such as heartburn, acid reflux, and indigestion. Learn about First-Lansoprazole uses, dosage, side effects, and acid reflux treatment options.
- Unusual bleeding, bruising, tiredness, or weakness
- Fever, swelling in your body, unusual weight gain, change in how much or how often you urinate, blood in the urine
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, or red skin rash
- Joint pain, rash on your cheeks or arms that gets worse in the sun
- Severe diarrhea that does not go away, stomach cramps or pain, nausea, vomiting, loss of appetite, weight loss
- Dry mouth, increased thirst, confusion, numbness and tingling around the mouth, fingertips, or feet
- Seizures, dizziness, fast or uneven heartbeat, muscle cramps or twitching
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, osteoporosis, vitamin B12 deficiency, or phenylketonuria (PKU).
- This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach)Increased risk for heart problems (including heart valve thickening) in children younger than 1 year of age
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
First-Lansoprazole Coupons & Prices
First-Lansoprazole
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Looking for a FIRST-Lansoprazole coupon? FIRST-Lansoprazole is a pharmacist compounding kit used to make a ready-to-dispense lansoprazole 3 mg/mL oral suspension, a proton pump inhibitor (PPI) for people who cannot swallow capsules or tablets. Rx.com offers a free cash coupon you can use at the pharmacy counter whether you are uninsured, on Medicare, or your insurance does not cover it. Enter your ZIP above to see today's price at pharmacies near you.
What is FIRST-Lansoprazole and how does it work?
FIRST-Lansoprazole is a unit-of-use kit that a pharmacist compounds into a ready-to-dispense lansoprazole 3 mg/mL oral suspension. It exists so patients who cannot swallow capsules or tablets, including those fed through a nasogastric (NG) tube, can still take lansoprazole. Lansoprazole itself is a proton pump inhibitor (PPI): it lowers the amount of acid the stomach makes, which lets irritated tissue heal.
Lansoprazole is FDA-approved to treat and to maintain healing of erosive esophagitis and gastroesophageal reflux disease (GERD), duodenal ulcers, benign gastric ulcers, and NSAID-associated gastric ulcers (both treatment and risk reduction). It is also used, with antibiotics such as amoxicillin (with or without clarithromycin), to eradicate Helicobacter pylori, and to manage pathologic hypersecretory conditions such as Zollinger-Ellison syndrome. Lansoprazole is also FDA-approved for short-term treatment of symptomatic GERD and erosive esophagitis in children ages 1 to 17; use in infants under 1 year of age is off-label, because studies did not find it effective in that group.
FIRST-Lansoprazole cost: manufacturer savings vs. Rx.com cash coupon
FIRST-Lansoprazole does not have a manufacturer copay savings card, and there is no official manufacturer savings program to enroll in. Manufacturer cards, when they exist, are generally limited to people with commercial (non-government) insurance and come with terms that vary, so they typically do not help if you are uninsured, on Medicare or Medicaid, or if the card is declined at the counter.
The Rx.com cash coupon works differently: it is a free discount you show at the pharmacy instead of using insurance, so it can help whether you are uninsured, on Medicare, or paying cash. The biggest savings lever here is that lansoprazole is available as a generic. Ask your pharmacist whether a generic lansoprazole capsule, orally disintegrating tablet (SoluTab), or a compounded generic suspension fits your needs, since generics usually cost far less than a branded kit. Enter your ZIP above to see today's price on both the FIRST-Lansoprazole kit and generic lansoprazole near you.
Alternatives and related PPIs
FIRST-Lansoprazole is essentially a delivery format for lansoprazole. If you can swallow pills, generic lansoprazole capsules or the Prevacid / Prevacid SoluTab brand cover the same uses. Other proton pump inhibitors in the same class include omeprazole and pantoprazole, and there is a comparable compounding kit, FIRST-Omeprazole, for patients who need an omeprazole suspension.
These medicines are similar but not identical, and drug interactions and insurance coverage differ between them. Your prescriber and pharmacist can help you pick the PPI and the form (capsule, disintegrating tablet, or suspension) that is right for you. Prices vary by drug and pharmacy, so it is worth comparing options with your ZIP above.
Safety and side effects
Lansoprazole has no boxed warning and is widely used, but PPIs carry class risks that mostly appear with high doses or long-term use (typically longer than a year). These can include a higher risk of osteoporosis-related fractures of the hip, wrist, and spine; low magnesium (hypomagnesemia), which may cause seizures or irregular heartbeats; vitamin B12 deficiency with prolonged use; Clostridioides difficile-associated diarrhea; and fundic gland polyps. Acute kidney inflammation (tubulointerstitial nephritis) and, rarely, cutaneous or systemic lupus and serious skin reactions can occur at any time. The general guidance is to use the lowest effective dose for the shortest time needed.
Because lansoprazole lowers stomach acid, it can affect medicines whose absorption depends on stomach acid, such as certain HIV antiretrovirals (for example atazanavir and nelfinavir), and it can affect drugs such as high-dose methotrexate and digoxin. Unlike omeprazole and esomeprazole, lansoprazole is not a strong inhibitor of the CYP2C19 enzyme, so it is generally considered one of the preferred PPIs for people who also take the blood thinner clopidogrel. This is general information, not medical advice. Tell your doctor and pharmacist about everything you take, and talk with your provider before starting, stopping, or changing lansoprazole.
This First-Lansoprazole information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: First-Lansoprazole on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.