Itraconazole
Itraconazole 100MG
What is Itraconazole?
Itraconazole is a generic drug used to treat patients with fungal infections. The average price of Itraconazole is about $516 for a supply of 60,100 mg capsules. You can use our Rx.com savings offer to get an average Itraconazole discount of up to 80% off of the retail price at participating pharmacies near you.Side Effects
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Numbness, tingling, or burning pain anywhere in your body
- Chest pain, trouble breathing, coughing up blood, cold sweat, bluish-colored skin
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, lung problems (including COPD), edema (body swelling), HIV infection or AIDS, or cystic fibrosis. Tell your doctor if you have had an organ transplant.
- This medicine may cause the following problems:New or worsening heart failureLiver problemsHeart rhythm problems, which can be life-threatening (when used with certain medicines)Nerve problemsTemporary or permanent hearing loss
- This medicine may make you feel dizzy or have blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Call your doctor if your symptoms do not improve or if they get worse.
Prescription savings · · · ·
What is Itraconazole ?
Itraconazole is a generic drug used to treat patients with fungal infections. The average price of Itraconazole is about $516 for a supply of 60,100 mg capsules. You can use our Rx.com savings offer to get an average Itraconazole discount of up to 80% off of the retail price at participating pharmacies near you.- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Numbness, tingling, or burning pain anywhere in your body
- Chest pain, trouble breathing, coughing up blood, cold sweat, bluish-colored skin
- Hearing loss
- Fast, pounding, or uneven heartbeat
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Rapid weight gain, swelling in your face, hands, ankles, or feet
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, lung problems (including COPD), edema (body swelling), HIV infection or AIDS, or cystic fibrosis. Tell your doctor if you have had an organ transplant.
- This medicine may cause the following problems:New or worsening heart failureLiver problemsHeart rhythm problems, which can be life-threatening (when used with certain medicines)Nerve problemsTemporary or permanent hearing loss
- This medicine may make you feel dizzy or have blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Call your doctor if your symptoms do not improve or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Numbness, tingling, or burning pain anywhere in your body
- Rapid weight gain, swelling in your face, hands, ankles, or feet
Itraconazole Coupons & Prices
Itraconazole 100MG
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Looking for an itraconazole coupon? Itraconazole is the generic form of the triazole antifungal sold under brand names like Sporanox, Tolsura, and Onmel, and because a generic is available it is often already lower-cost than the brand. Even so, the cash price can vary widely from one pharmacy to the next, so comparing matters. Rx.com checks prices across more than 60,000 pharmacies so you can find a low price near you. Enter your ZIP above to see today's price and print or show your free discount at the pharmacy counter.
What is itraconazole and how does it work?
Itraconazole is a prescription antifungal medicine in the triazole (azole) class. It works by interfering with the fungal cell membrane, which stops the fungus from growing and helps your body clear the infection. It is used to treat a range of fungal infections, including blastomycosis (in the lungs and other parts of the body), histoplasmosis, and aspergillosis in people who cannot take or did not respond to amphotericin B. It is also used for onychomycosis, which is a fungal infection of the toenail or fingernail, and, as the oral solution, for oropharyngeal and esophageal candidiasis (yeast infections of the mouth and throat).
Itraconazole comes in different forms, including capsules and an oral solution. It is important to know that Sporanox and Tolsura are not interchangeable, so your pharmacist should fill exactly what your prescriber ordered. Always follow your provider's directions for your specific product and dose.
Itraconazole cost and savings without insurance
Because itraconazole is available as a generic, it is usually more affordable than its brand-name equivalents. Still, the cash price is not the same everywhere. Different pharmacies set very different prices for the same medication, and the form (capsule versus oral solution) also affects cost, so it pays to compare before you fill. A free Rx.com discount can be used whether or not you have insurance, and in some cases the discounted cash price beats an insurance copay.
To see current pricing, enter your ZIP above and Rx.com will compare itraconazole prices across more than 60,000 pharmacies near you. The brand-name maker of Tolsura also lists a savings program on its official website (tolsura.com), and program terms and eligibility vary, so check the manufacturer's site for details.
Itraconazole vs. other antifungals
Itraconazole is one of several antifungal medicines, and the right choice depends on the type of infection and your health history. Your prescriber may consider alternatives such as fluconazole, ketoconazole, voriconazole, or, for nail and skin infections, terbinafine. Each has its own uses, dosing, and interaction profile.
If your prescription is written for a brand, you can also compare it with the branded versions Sporanox and Tolsura. This page is for information only and is not medical advice; only your doctor or pharmacist can decide which antifungal is right for you.
Safety and important warnings
Itraconazole has two boxed warnings, which are the strongest warnings the FDA issues. First, it should not be used for fungal nail infections in people who have signs of heart problems such as congestive heart failure (CHF) or a history of CHF, because itraconazole can weaken the heart's pumping and has been linked to heart failure and fluid buildup (swelling in the legs or lungs). Second, taking itraconazole with certain other medicines processed by the liver enzyme CYP3A4, such as some cholesterol statins, cisapride, dofetilide, and quinidine, can cause dangerous heart rhythm changes (QT prolongation and a rhythm called torsades de pointes). Itraconazole has many other CYP3A4 drug interactions as well.
Other risks include serious liver injury (including rare fatal cases) and hearing loss, and itraconazole is generally avoided in pregnancy because of possible harm to the baby, especially when used for nail infections. Give your provider a full list of every medicine and supplement you take before starting itraconazole, and tell them about any heart, liver, or hearing conditions. Contact your provider promptly if you notice signs of a problem such as unusual tiredness, yellowing of the skin or eyes, dark urine, swelling, shortness of breath, or hearing changes. This is general information, not medical advice.
This Itraconazole information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Itraconazole on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.