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Lidocaine-Prilocaine Tube Of Cream — prescription drug image

Lidocaine-Prilocaine

Lidocaine-Prilocaine (Livixil Pak)

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What is Lidocaine-Prilocaine?

Lidocaine-Prilocaine Cream (EMLA) is a prescription topical anesthetic used to numb the skin before medical procedures such as injections, blood draws, IV placement, laser treatments, and minor skin surgeries. It combines two local anesthetics to temporarily reduce pain and discomfort at the application site.

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What is Lidocaine-Prilocaine ?

Lidocaine-Prilocaine Cream (EMLA) is a prescription topical anesthetic used to numb the skin before medical procedures such as injections, blood draws, IV placement, laser treatments, and minor skin surgeries. It combines two local anesthetics to temporarily reduce pain and discomfort at the application site.

  • Redness or pale skin at the application site
  • Mild burning or stinging sensation
  • Swelling at the site of application
  • Bruising or unusual sensations on the skin (tingling, itching)
  • Changes in skin color at the site of application
  • Blistering or peeling skin
  • Avoid contact with eyes. In case of accidental contact, rinse eyes thoroughly with water.
  • Do not apply to broken or inflamed skin.
  • Use with caution if you have a history of severe liver disease or methemoglobinemia.
  • Do not use for prolonged periods or in large amounts without consulting a doctor.
  • Seek immediate medical attention if experiencing difficulty breathing, face, lip, or tongue swelling, dizziness, or rash.
  • Consult your doctor before using if pregnant or breastfeeding.
What is lidocaine and prilocaine cream used for?
Lidocaine and prilocaine cream (EMLA) is a topical anesthetic used to numb the skin before minor procedures such as needle sticks, blood draws, IV placement, and superficial skin surgery, and it can be used on genital mucous membranes before certain minor procedures. The periodontal gel form (Oraqix) is used to numb periodontal pockets during dental scaling and root planing. Your provider will tell you which form fits your situation.
How long does it take for lidocaine-prilocaine (EMLA) cream to numb the skin?
EMLA cream is applied ahead of time and left in place under a covering so it can take effect before the procedure. The exact application time depends on the procedure and the area being treated, so follow the directions on your product label or the instructions given by your provider or pharmacist rather than guessing.
Is lidocaine-prilocaine cream available over the counter or by prescription only?
The lidocaine and prilocaine 2.5%/2.5% products discussed here, EMLA cream and the Oraqix periodontal gel, are FDA-approved prescription products. Ask your provider or pharmacist whether it is right for you and how to use it correctly.
What are the side effects of lidocaine and prilocaine cream?
Common local side effects are usually temporary and include paleness, redness, swelling, burning, or itching at the site of application. The most serious risk is methemoglobinemia, a blood disorder whose signs can include pale, gray, or blue skin, headache, rapid heart rate, shortness of breath, lightheadedness, and fatigue; these can appear hours later and need immediate medical care. Seek help right away if they occur, and do not apply more than directed.
Can lidocaine-prilocaine cream be used on children and babies?
It can be used in children under a provider's guidance, but there is a higher risk of methemoglobinemia in infants, especially those under 12 months and particularly under 6 months of age. Because of this and the risk of too much being absorbed, it should only be used in babies and young children exactly as a healthcare provider directs. Talk to your child's doctor before using it.
How much does Lidocaine-Prilocaine 30GM of 2.5-2.5% cost without insurance?
The price of Lidocaine-Prilocaine 30GM of 2.5-2.5% without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Lidocaine-Prilocaine 30GM of 2.5-2.5%?
Common side effects of Lidocaine-Prilocaine 30GM of 2.5-2.5% may include: Redness or pale skin at the application site, Mild burning or stinging sensation, Swelling at the site of application, Bruising or unusual sensations on the skin (tingling, itching), Changes in skin color at the site of application. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Lidocaine-Prilocaine 30GM of 2.5-2.5%?
Generic versions may be available for Lidocaine-Prilocaine 30GM of 2.5-2.5%. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Lidocaine-Prilocaine 30GM of 2.5-2.5% on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Lidocaine-Prilocaine 30GM of 2.5-2.5%?
The cheapest pharmacy for Lidocaine-Prilocaine 30GM of 2.5-2.5% depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Lidocaine-Prilocaine 30GM of 2.5-2.5% near you.

Lidocaine-Prilocaine Coupons & Prices

Lidocaine-Prilocaine (Livixil Pak)

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Lidocaine-Prilocaine Tube Of Cream — prescription drug image
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Lidocaine-Prilocaine prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
5gm of 2.5-2.5% · Tube Of Cream 30 $86.39 $15.29
30gm of 2.5-2.5% · Tube Of Cream 30 $49.99 $15.29

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a lidocaine-prilocaine coupon? Lidocaine and prilocaine (brand names EMLA and Oraqix) is a topical local anesthetic combination used to numb the skin or gum tissue before minor procedures. It is available as a lower-cost generic, but the cash price can vary widely from one pharmacy to another, so comparing matters. Rx.com checks prices across more than 60,000 pharmacies so you can find the best price near you. Enter your ZIP above to see today's price at pharmacies in your area.

What is lidocaine and prilocaine, and how does it work?

Lidocaine and prilocaine is a combination of two amide-type local anesthetics applied to the surface of the body rather than swallowed or injected. It temporarily blocks nerve signals in the treated area, producing local numbness so a procedure can be done with less pain.

The 2.5%/2.5% cream (EMLA) is FDA-approved for use on normal intact skin to provide local numbing before minor procedures such as needle insertion, venipuncture (blood draws), IV placement, and superficial skin surgery, and on genital mucous membranes before superficial minor surgery or as pretreatment for infiltration anesthesia. The periodontal gel form (Oraqix, 2.5%/2.5%) is approved to provide localized numbing in periodontal pockets during scaling and root planing at the dentist. Your provider or pharmacist can confirm which form and strength is right for your situation.

Lidocaine-prilocaine cost and savings without insurance

Lidocaine and prilocaine is available as a generic, which typically keeps it more affordable than a brand-name product. Even so, the cash price is not the same everywhere. Without insurance, what one pharmacy charges for the same tube or gel can differ from the pharmacy down the street, which is exactly why comparing prices is worth the few seconds it takes.

Rx.com compares live prices across 60,000+ pharmacies and shows you a coupon you can bring to the counter. There is no membership fee to use it. Enter your ZIP above to see today's price near you and pick the lowest option. Prices change, so we show them live on the page rather than quoting a fixed figure.

Related drugs and alternatives

Lidocaine and prilocaine combines two anesthetics that are also available on their own: lidocaine and prilocaine. The best-known brand of this specific combination is EMLA.

Other topical local anesthetics used to numb skin or surfaces include benzocaine and tetracaine. These products differ in their approved uses, strengths, and how they are applied, so which one is appropriate depends on the procedure and your provider's guidance. If you have a prescription for a specific product, you can compare its price using the tool above.

Safety and side effects

The most important risk with lidocaine and prilocaine is methemoglobinemia, a serious blood disorder that reduces how well the blood carries oxygen. Warning signs include pale, gray, or blue-tinged skin, headache, rapid heartbeat, shortness of breath, lightheadedness, and unusual tiredness. These symptoms can appear hours after the product is applied and need immediate medical attention. The risk is higher in infants under 12 months (especially under 6 months), people with G6PD deficiency, those with congenital or idiopathic methemoglobinemia, people with heart or lung problems, and anyone taking other medicines that can raise methemoglobin levels.

To use it safely, do not apply it to large areas of skin or leave it on longer than directed, and keep it away from the eyes. Applying too much can lead to nervous system or heart-related effects from the medicine being absorbed into the body. Common, usually temporary local reactions include paleness, redness, swelling, burning, or itching where it was applied. This information is for general education and is not medical advice; follow your provider's or pharmacist's directions and talk to them about your specific health situation.

Sources & accuracy

This Lidocaine-Prilocaine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Lidocaine-Prilocaine on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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