Shingrix
Shingrix 50MCG/0.5ML
What is Shingrix?
Shingrix is a vaccine that helps prevent shingles, a painful skin rash caused by the same virus that leads to chickenpox. It can also help reduce the risk of long-lasting nerve pain that may occur after shingles.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Sudden numbness or weakness in your arms or legs
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have a weak immune system.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- This vaccine may increase your risk for nervous system problems, including Guillain-Barré syndrome.
Prescription savings · · · ·
What is Shingrix ?
Shingrix is a vaccine that helps prevent shingles, a painful skin rash caused by the same virus that leads to chickenpox. It can also help reduce the risk of long-lasting nerve pain that may occur after shingles.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Sudden numbness or weakness in your arms or legs
- Tell your doctor if you are pregnant or breastfeeding, or if you have a weak immune system.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- This vaccine may increase your risk for nervous system problems, including Guillain-Barré syndrome.
Shingrix Coupons & Prices
Shingrix 50MCG/0.5ML
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Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a Shingrix coupon? Shingrix is the brand-name recombinant zoster vaccine (RZV) that is FDA-approved to help prevent shingles (herpes zoster) in adults 50 and older, as well as in adults 18 and older who are at increased risk of shingles because of a weakened immune system. It is given as a two-dose series and has no generic version. Because it is often billed as a pharmacy vaccine, the price you pay can vary a lot from one location to another. Enter your ZIP above to see today's Rx.com cash price at pharmacies near you and compare it against what you would pay out of pocket.
What is Shingrix and how does it work?
Shingrix (recombinant zoster vaccine, adjuvanted with AS01B) is a non-live, recombinant subunit vaccine used to prevent shingles, the painful rash caused by reactivation of the same virus that causes chickenpox. Because it is not a live vaccine, it can be given to people whose immune systems are weakened. It is given as a two-dose series: the second dose normally follows 2 to 6 months after the first, and immunocompromised patients may use a shortened 1-to-2-month interval.
Shingrix is FDA-approved to prevent shingles in adults 50 and older, and in adults 18 and older who are or will be at increased risk of shingles due to immunodeficiency or immunosuppression from a disease or its treatment. It is not used to prevent primary chickenpox (varicella), and it does not treat an active shingles outbreak or the lingering nerve pain (postherpetic neuralgia) that can follow one.
Shingrix cost: manufacturer support vs. an Rx.com cash coupon
Shingrix does not have a generic, so there is no lower-cost substitute at the pharmacy counter, and the manufacturer (GSK) does not offer a general commercial copay savings card for it the way some brand medications do. Many people are covered for Shingrix at no cost through Medicare Part D or commercial insurance, but coverage and out-of-pocket costs vary by plan, so it is worth confirming your benefit before you go.
If you are uninsured, between plans, or your coverage does not pick up the full cost, an Rx.com cash coupon can help. Our coupon is a cash-price discount you can use whether or not you have insurance, and it is handy when a plan will not cover the dose or you want to compare the cash price. GSK also runs a patient-assistance program, GSK for You, for eligible people who cannot afford their medicines; eligibility and terms are set by the manufacturer and can change, so check their official site for current details. To see your price, enter your ZIP above and compare pharmacies near you.
How Shingrix compares to other shingles vaccines
Shingrix is currently the only shingles vaccine marketed in the United States. The older live vaccine, Zostavax, was discontinued and is no longer sold in the U.S., so Shingrix is the recommended option for eligible adults. Because Shingrix is not a live vaccine, it can be given to people with weakened immune systems, which the older live vaccine could not.
Shingrix protects against shingles, not chickenpox, and it is not interchangeable with the childhood chickenpox (varicella) vaccine. Talk with your pharmacist or provider about the right timing if you have had shingles before or received the older vaccine in the past.
Shingrix safety and side effects
Shingrix has no boxed warning. The most common reactions are soreness, redness, and swelling where the shot is given, along with body-wide effects such as muscle aches, tiredness, headache, shivering, fever, and upset stomach. These usually clear up within 2 to 3 days. About 1 in 6 people have reactions strong enough to briefly limit their normal activities, which is a sign your immune system is responding.
An increased risk of Guillain-Barre syndrome (GBS) has been observed within 42 days after vaccination and is noted on the label. Fainting (syncope) can happen with any injection, and rare severe allergic reactions are possible. Shingrix should not be given to anyone with a history of a severe allergic reaction to any ingredient in the vaccine or to a previous dose. This information is not medical advice; talk with your provider or pharmacist about whether Shingrix is right for you.
This Shingrix information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Shingrix on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.