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Simethicone

Simethicone 100 Tablets Chewable

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What is Simethicone?

Simethicone is a chewable medication used to relieve discomfort caused by gas, such as pressure, fullness, and bloating. It helps break up gas bubbles in the stomach and intestines, making it easier to pass gas.

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What is Simethicone ?

Simethicone is a chewable medication used to relieve discomfort caused by gas, such as pressure, fullness, and bloating. It helps break up gas bubbles in the stomach and intestines, making it easier to pass gas.

Source: MedlinePlus, U.S. National Library of Medicine

  • Mild diarrhea
  • Heartburn
  • Talk to your doctor if you have problems with gas often. There may be a serious but treatable cause.
  • No severe side effects have been reported with the use of simethicone.
  • You should not use more of this medicine in a 24-hour period than your doctor orders, or more than the dose listed on the medicine label directions.
  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
What is simethicone used for?
Simethicone is an over-the-counter anti-gas medicine used to relieve the symptoms of excess gas in the digestive tract, such as uncomfortable pressure, fullness, and bloating. It works as an antifoaming agent, helping small gas bubbles combine into larger ones that are easier to pass.
How quickly does simethicone work?
Simethicone acts directly in the stomach and intestines rather than being absorbed by the body, so many people notice relief from trapped-gas symptoms fairly soon after taking it. Results vary from person to person, and it only helps with the bubble-related gas it is designed to treat. If your symptoms do not improve, check with your doctor or pharmacist.
Is simethicone safe to take every day?
Simethicone is generally considered very safe and well tolerated because it is not absorbed into the bloodstream, and when taken as directed it usually causes no side effects. Still, ongoing gas symptoms can have an underlying cause, so if you find you need it for more than a few days, or your symptoms are severe or persistent, talk with your doctor rather than relying on it long term. This is general information, not medical advice.
Can I give simethicone to my baby for gas?
There is an infant liquid-drop form of simethicone (such as Infants' Mylicon) intended for babies with gas symptoms. If you use it, make sure you have the correct infant product and concentration and follow the pediatric dosing directions on the label. When in doubt, ask your pediatrician or pharmacist before giving it to your child.
What is the difference between simethicone and an antacid?
Simethicone treats gas by breaking up trapped bubbles, while an antacid neutralizes or reduces stomach acid to relieve heartburn and acid indigestion. They address different problems, though simethicone is sometimes combined with an antacid in a single product. If you are unsure which one fits your symptoms, a pharmacist can help you choose.
How much does Simethicone cost without insurance?
The price of Simethicone without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 63% off retail prices with a free Rx.com coupon.
What are the common side effects of Simethicone?
Common side effects of Simethicone may include: Mild diarrhea, Heartburn. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Simethicone?
Generic versions may be available for Simethicone. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Simethicone on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Simethicone?
The cheapest pharmacy for Simethicone depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Simethicone near you.

Simethicone Coupons & Prices

Simethicone 100 Tablets Chewable

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Looking for a simethicone coupon? Simethicone is an inexpensive, over-the-counter anti-gas medicine (sold under brands like Gas-X, Mylicon, Phazyme, and Mylanta Gas) that eases the pressure, fullness, and bloating caused by too much gas in your digestive tract. It is widely available without a prescription and already low-cost, but prices still vary by pharmacy and package size, so it can pay to compare. Enter your ZIP above to see today's price and print or show a free Rx.com discount coupon at the register.

What is simethicone and how does it work?

Simethicone is an antiflatulent, also called an anti-gas or antifoaming agent. It is the active ingredient in familiar brands such as Gas-X, Mylicon, Mylanta Gas, Maalox Anti-Gas, Phazyme, and Alka-Seltzer Anti-Gas, and it is also sold as an inexpensive store-brand generic. It relieves the symptoms of excess gas in the stomach and intestines, including uncomfortable or painful pressure, fullness, and bloating.

Rather than being absorbed into your body, simethicone works right in the digestive tract. It acts on the small gas bubbles trapped in stomach and intestinal contents, helping them join together into larger bubbles that pass more easily, either as a burp or through the rectum. Because it targets bubble formation, it is not effective for discomfort from swallowed air that is unrelated to those trapped bubbles.

How to use simethicone

Simethicone comes in several forms, including chewable tablets, softgels, and liquid drops. It is usually taken after meals and at bedtime, or as directed on the package, and chewable tablets should be chewed thoroughly before swallowing. Always follow the directions on the label or your pharmacist's guidance for the specific product you buy.

An infant liquid-drop form (such as Infants' Mylicon) is made for babies with gas symptoms. If you are giving it to an infant, confirm you have the correct product and concentration and follow the pediatric dosing on the label. This is general information, not medical advice; check with your doctor or pharmacist if you are unsure.

Saving on simethicone with an Rx.com coupon

Simethicone is one of the more affordable pharmacy staples, but the shelf price still differs from store to store and between name brands and generics. The store-brand generic almost always costs less than a name brand like Gas-X or Phazyme and contains the same active ingredient at the same strength. Buying the concentration and package size that fit how often you actually use it can also help you avoid overpaying.

Some OTC items are cheaper with a discount coupon, or when your provider writes them as a prescription so you can run them through a savings program. Enter your ZIP above to see today's price near you and to pull up a free Rx.com discount coupon you can show at the pharmacy counter. There is no manufacturer copay card for a low-cost OTC ingredient like this; the coupon simply helps you compare and pay a competitive cash price.

Simethicone vs. antacids and other stomach remedies

Simethicone treats gas, not acid, so it is different from medicines that neutralize or reduce stomach acid. It is sometimes included alongside an antacid in combination products, but on its own it does nothing for heartburn or reflux. Choosing the right medicine depends on your symptom:

If you are not sure whether your discomfort is gas, acid, or something else, ask a pharmacist which product fits your symptoms.

Safety and when to talk to your doctor

Simethicone is considered very safe and is generally well tolerated. Because it is not absorbed into the bloodstream, taking it as directed usually causes no side effects; mild diarrhea has been reported only rarely. It carries no boxed warning. Even so, it is not a substitute for having ongoing or severe abdominal symptoms evaluated by a professional.

Talk with your doctor before continuing if your symptoms last more than a few days, and seek care for severe or persistent abdominal pain. For infants, confirm the correct product and concentration and follow the pediatric dosing on the label. This information is not medical advice; your provider or pharmacist can help you decide whether simethicone is right for you.

Sources & accuracy

This Simethicone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Simethicone on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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