Adapalene-Benzoyl Peroxide
Adapalene-Benzoyl Peroxide 45GM of 0.1-2.5%
What is Adapalene-Benzoyl Peroxide?
Adapalene-Benzoyl Peroxide is a topical acne agent used to treat severe acne. Adapalene-Benzoyl Peroxide is a generic drug. You can use our Rx.com Adapalene-Benzoyl Peroxide savings card to save significantly on the retail price at participating pharmacies near you.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe redness or swelling of the skin
- Blistering, burning, crusting, dryness, or flaking of the skin
Warnings
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined. Do not use this medicine if you have a sunburn or eczema.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- You may need to use this medicine for several weeks or months before your skin starts to look better.
- Allow this medicine to dry completely before you get dressed. This medicine may cause bleaching of clothes or hair.
- Tell your doctor if you are pregnant or breastfeeding.
Prescription savings · · · ·
What is Adapalene-Benzoyl Peroxide ?
Adapalene-Benzoyl Peroxide is a topical acne agent used to treat severe acne. Adapalene-Benzoyl Peroxide is a generic drug. You can use our Rx.com Adapalene-Benzoyl Peroxide savings card to save significantly on the retail price at participating pharmacies near you.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Severe redness or swelling of the skin
- Blistering, burning, crusting, dryness, or flaking of the skin
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined. Do not use this medicine if you have a sunburn or eczema.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- You may need to use this medicine for several weeks or months before your skin starts to look better.
- Allow this medicine to dry completely before you get dressed. This medicine may cause bleaching of clothes or hair.
- Tell your doctor if you are pregnant or breastfeeding.
- This medicine may make your skin more sensitive to sunlight, wind, and cold weather. Use sunscreen when you are outdoors, and wear protective clothing, such as a hat. Do not use a sunlamp or tanning bed.
- Use a moisturizer as needed if your skin becomes irritated.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Do not use waxing as a hair removal method on skin areas treated with this medicine.
Adapalene-Benzoyl Peroxide Coupons & Prices
Adapalene-Benzoyl Peroxide 45GM of 0.1-2.5%
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for an adapalene-benzoyl-peroxide coupon? This once-daily topical acne gel is the generic form of Epiduo and Epiduo Forte, and because it is a generic it already tends to cost far less than the brand. Cash prices still vary widely from one pharmacy to the next, so it pays to compare. Rx.com checks prices across more than 60,000 pharmacies so you can find today's lowest cost near you. Enter your ZIP above to see today's price and print or text yourself a free discount coupon.
What is adapalene-benzoyl peroxide and how does it work?
Adapalene / benzoyl peroxide is a combination gel FDA-approved for the topical treatment of acne vulgaris. It pairs two acne fighters in one product: adapalene, a retinoid that helps normalize skin-cell turnover and reduce inflammation, and benzoyl peroxide, which kills acne-causing bacteria (Cutibacterium acnes) and helps clear clogged pores. It is the generic equivalent of the brands Differin-family products marketed as Epiduo and Epiduo Forte.
The 0.1%/2.5% strength (Epiduo) is approved for patients 9 years and older, and the stronger 0.3%/2.5% strength (Epiduo Forte) is approved for patients 12 and older. It is applied as a thin film once daily to the affected areas of clean, dry skin. Follow your prescriber's or pharmacist's directions for the strength you were given.
How much does adapalene-benzoyl peroxide cost without insurance?
Because a generic version is available, adapalene / benzoyl peroxide is usually much cheaper than the Epiduo or Epiduo Forte brand. Even so, the cash price without insurance can differ a lot depending on which pharmacy you use and which strength you were prescribed, so comparing before you fill matters. Rx.com compares prices across more than 60,000 U.S. pharmacies and gives you a free discount coupon you can use whether or not you have insurance. Enter your ZIP above to see today's price near you.
If you were prescribed the brand, the manufacturer (Galderma) offers a savings program on its official Epiduo Forte website; program terms and eligibility vary and can change, so check the manufacturer's site for current details. For the generic, the Rx.com discount price is often the simplest way to keep costs down at the counter.
Alternatives and related acne treatments
Adapalene / benzoyl peroxide combines two ingredients, but each is also available on its own, and other prescription acne options work in similar ways. Depending on your skin and what your provider recommends, related treatments include:
- adapalene — the retinoid used alone
- benzoyl peroxide — the antibacterial ingredient used alone
- tretinoin — another topical retinoid
- tazarotene — a topical retinoid
- clindamycin / benzoyl peroxide — an antibiotic-plus-benzoyl-peroxide combination
Which option is right for you depends on your acne and medical history. This is general information, not medical advice, so talk with your provider or pharmacist before switching products. Whichever you fill, you can compare its price on Rx.com.
Safety and side effects
Adapalene / benzoyl peroxide has no boxed warning. It is for external use only — avoid contact with the eyes, lips, mouth, and other mucous membranes, and do not apply it to skin that is cut, scraped, sunburned, or affected by eczema. The most common effects are local skin irritation: dryness, redness, scaling, and stinging or burning, plus possible contact dermatitis. These are usually worst during the first few weeks and often ease as your skin adjusts.
Two practical cautions: benzoyl peroxide can bleach hair and dyed fabrics, so let it dry and be careful around towels and pillowcases; and this medicine can make your skin more sensitive to the sun, so limit UV exposure and use sunscreen. Rare but serious allergic reactions have been reported — stop use and get medical care right away if you notice swelling, hives, or trouble breathing. This is general information and not a substitute for your prescriber's advice, so follow the product directions and ask your provider or pharmacist with any questions.
This Adapalene-Benzoyl Peroxide information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Adapalene-Benzoyl Peroxide on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Related Drugs
Browse more medications: starting with A · full A-Z directory · by condition · common drugs
Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.