Baclofen
Baclofen 10MG
What is Baclofen?
Baclofen is a prescription muscle relaxant and antispastic agent used to treat muscle spasticity — the stiffness, tightness, and involuntary muscle spasms caused by neurological conditions including multiple sclerosis (MS), spinal cord injury, and other disorders affecting the spinal cord. It is also sometimes used off-label for alcohol use disorder and certain pain conditions. Baclofen works on the central nervous system by activating GABA-B receptors in the spinal cord, which inhibits the nerve signals that cause muscles to contract involuntarily. Oral doses typically start at 5 mg three times daily and can be gradually increased to 80 mg per day based on response. A licensed provider can prescribe baclofen through Rx.com if it is right for your condition. Generic baclofen is highly affordable with an Rx.com discount coupon.
Side Effects
- Drowsiness
- Dizziness
- Confusion
Warnings
- Do not suddenly stop taking Baclofen without consulting your doctor as it may lead to withdrawal symptoms such as seizures and hallucinations.
- Use caution when driving or operating heavy machinery as Baclofen can impair your ability to perform these tasks.
- Avoid consuming alcohol while taking Baclofen as it can enhance the sedative effects.
- Baclofen may not be suitable for individuals with kidney problems or seizures.
Prescription savings · · · ·
What is Baclofen ?
Baclofen is a prescription muscle relaxant and antispastic agent used to treat muscle spasticity — the stiffness, tightness, and involuntary muscle spasms caused by neurological conditions including multiple sclerosis (MS), spinal cord injury, and other disorders affecting the spinal cord. It is also sometimes used off-label for alcohol use disorder and certain pain conditions. Baclofen works on the central nervous system by activating GABA-B receptors in the spinal cord, which inhibits the nerve signals that cause muscles to contract involuntarily. Oral doses typically start at 5 mg three times daily and can be gradually increased to 80 mg per day based on response. A licensed provider can prescribe baclofen through Rx.com if it is right for your condition. Generic baclofen is highly affordable with an Rx.com discount coupon.
- Drowsiness
- Dizziness
- Confusion
- Weakness
- Headache
- Nausea
- Constipation
- Fatigue
- Trouble sleeping
- Do not suddenly stop taking Baclofen without consulting your doctor as it may lead to withdrawal symptoms such as seizures and hallucinations.
- Use caution when driving or operating heavy machinery as Baclofen can impair your ability to perform these tasks.
- Avoid consuming alcohol while taking Baclofen as it can enhance the sedative effects.
- Baclofen may not be suitable for individuals with kidney problems or seizures.
Baclofen Coupons & Prices
Baclofen 10MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a baclofen coupon? Baclofen is a widely used generic muscle relaxant, and because it is generic it is already one of the lower-cost prescriptions at most pharmacies. But the cash price still swings a lot from one pharmacy to the next, so it pays to compare before you fill. Enter your ZIP above to see today's price and a free Rx.com discount coupon you can use at the counter. Rx.com compares prices across more than 60,000 pharmacies so you can find the lowest cash price near you.
What is baclofen and how does it work?
Baclofen is a skeletal muscle relaxant, also called an antispastic agent. It works as a GABA-B receptor agonist in the spinal cord, calming the nerve signals that cause muscles to tighten and spasm. It is FDA-approved to treat spasticity — muscle spasm, clonus, cramping, tightness, and pain — that results from multiple sclerosis and from spinal cord injuries or diseases. Oral baclofen is used in patients 12 years and older.
Baclofen comes in several forms. The oral tablet is the common generic, and there are also branded oral options such as Ozobax and Ozobax DS (oral solution), Fleqsuvy (oral suspension), and Lyvispah (oral granules). A separate form, Gablofen, is given as an intrathecal injection through a surgically implanted pump for severe spasticity of spinal or cerebral origin, including cerebral palsy, when oral therapy fails or is not tolerated. The original brand Lioresal (oral) has been discontinued.
Baclofen cost and savings without insurance
Baclofen is available as an FDA-approved generic, which is why it is usually inexpensive compared with brand-name muscle relaxants. Even so, the cash price is not the same everywhere — different pharmacies can charge very different amounts for the exact same tablet, so comparing is the single best way to save. If you have no insurance, or your plan does not cover it well, a free discount coupon can often beat the standard shelf price.
The branded oral forms (Ozobax, Fleqsuvy, Lyvispah) generally cost more than the generic tablet. There is no manufacturer copay savings card for generic baclofen. To find the best price for your form and dose, enter your ZIP above to see today's price and print or show your Rx.com coupon at the pharmacy.
Baclofen vs. other muscle relaxants
Baclofen is one of several muscle relaxants your prescriber might consider, and each works a little differently. The closest comparison is tizanidine, which, like baclofen, is often used for spasticity but acts as an alpha-2 agonist and tends to be shorter-acting. Others are used mainly for short-term relief of muscle spasm from strains and injuries rather than for chronic spasticity.
- Tizanidine — often used for spasticity; shorter-acting
- Cyclobenzaprine — commonly used short-term for acute muscle spasm
- Methocarbamol — used for short-term muscle spasm relief
- Carisoprodol — a controlled substance used short-term for muscle spasm
- Metaxalone — used short-term for muscle spasm, often chosen for lower sedation
All of these are generic, and prices vary by pharmacy, so it is worth comparing whichever one you are prescribed. Only your provider can decide which is right for you.
Baclofen safety and important warnings
Do not stop baclofen suddenly. For oral baclofen, stopping abruptly can trigger withdrawal — including seizures, hallucinations, and a rebound worsening of spasticity — so it should be tapered under your prescriber's guidance. Intrathecal baclofen (the implanted-pump form) carries an FDA boxed warning: abrupt loss of the drug, often from a pump or catheter malfunction, a dosing error, or a low reservoir, can cause life-threatening withdrawal with high fever, altered mental status, severe rebound spasticity and muscle rigidity, and rarely rhabdomyolysis, organ failure, and death.
Baclofen causes CNS depression — drowsiness, dizziness, sedation, and weakness — and these effects add up when combined with alcohol or other sedating medicines. Avoid driving until you know how it affects you. Use extra caution in older adults, in people with seizure disorders, and in those with kidney problems, since baclofen is cleared by the kidneys and may need a lower dose. Overdose can cause dangerous breathing problems and coma. This information is not medical advice — talk with your doctor or pharmacist about your full medication list and any conditions before starting or changing baclofen.
This Baclofen information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Baclofen on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.