Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Baclofen Vial — prescription drug image

Baclofen

Baclofen 10MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Baclofen?

Baclofen is a prescription muscle relaxant and antispastic agent used to treat muscle spasticity — the stiffness, tightness, and involuntary muscle spasms caused by neurological conditions including multiple sclerosis (MS), spinal cord injury, and other disorders affecting the spinal cord. It is also sometimes used off-label for alcohol use disorder and certain pain conditions. Baclofen works on the central nervous system by activating GABA-B receptors in the spinal cord, which inhibits the nerve signals that cause muscles to contract involuntarily. Oral doses typically start at 5 mg three times daily and can be gradually increased to 80 mg per day based on response. A licensed provider can prescribe baclofen through Rx.com if it is right for your condition. Generic baclofen is highly affordable with an Rx.com discount coupon.

Prescription savings · · · ·

What is Baclofen ?

Baclofen is a prescription muscle relaxant and antispastic agent used to treat muscle spasticity — the stiffness, tightness, and involuntary muscle spasms caused by neurological conditions including multiple sclerosis (MS), spinal cord injury, and other disorders affecting the spinal cord. It is also sometimes used off-label for alcohol use disorder and certain pain conditions. Baclofen works on the central nervous system by activating GABA-B receptors in the spinal cord, which inhibits the nerve signals that cause muscles to contract involuntarily. Oral doses typically start at 5 mg three times daily and can be gradually increased to 80 mg per day based on response. A licensed provider can prescribe baclofen through Rx.com if it is right for your condition. Generic baclofen is highly affordable with an Rx.com discount coupon.

  • Drowsiness
  • Dizziness
  • Confusion
  • Weakness
  • Headache
  • Nausea
  • Constipation
  • Fatigue
  • Trouble sleeping
  • Do not suddenly stop taking Baclofen without consulting your doctor as it may lead to withdrawal symptoms such as seizures and hallucinations.
  • Use caution when driving or operating heavy machinery as Baclofen can impair your ability to perform these tasks.
  • Avoid consuming alcohol while taking Baclofen as it can enhance the sedative effects.
  • Baclofen may not be suitable for individuals with kidney problems or seizures.
What is baclofen used for?
Baclofen is FDA-approved to treat spasticity — muscle spasm, clonus, cramping, tightness, and pain — from multiple sclerosis and from spinal cord injuries or diseases. Oral baclofen is used in people 12 years and older. The intrathecal (implanted-pump) form is used for severe spasticity of spinal or cerebral origin, including cerebral palsy, when oral therapy does not work or is not tolerated.
Is baclofen a narcotic or controlled substance?
No. Baclofen is not a narcotic and is not a federally controlled substance. It is a muscle relaxant (a GABA-B receptor agonist). Even so, it should not be stopped abruptly, because doing so can cause withdrawal symptoms.
How long does it take for baclofen to work?
Baclofen is usually started at a low dose and increased gradually, so it can take days to a few weeks to reach a dose that eases your spasticity. Individual timing varies, so follow your prescriber's dosing schedule rather than increasing the dose on your own.
Can you stop taking baclofen suddenly?
No. Do not stop baclofen suddenly. Abruptly stopping oral baclofen can cause withdrawal, including seizures, hallucinations, and a rebound worsening of spasticity. With the intrathecal pump form, sudden loss of the drug can cause life-threatening withdrawal. Any change should be a gradual taper guided by your provider.
What is the difference between baclofen and tizanidine?
Both baclofen and tizanidine are muscle relaxants used for spasticity, but they work differently: baclofen is a GABA-B receptor agonist, while tizanidine is an alpha-2 agonist that tends to be shorter-acting. Both can cause drowsiness. Which one is better depends on your situation, so your prescriber will help you choose.
How much does Baclofen 10MG cost without insurance?
The price of Baclofen 10MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Baclofen 10MG?
Common side effects of Baclofen 10MG may include: Drowsiness, Dizziness, Confusion, Weakness, Headache. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Baclofen 10MG?
Generic versions may be available for Baclofen 10MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Baclofen 10MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Baclofen 10MG?
The cheapest pharmacy for Baclofen 10MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Baclofen 10MG near you.

Baclofen Coupons & Prices

Baclofen 10MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Baclofen Vial — prescription drug image
Prescription
Baclofen 20ml of 40mg/20ml (2)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

Licensed U.S. providers · No insurance needed · Shipped to your door

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a baclofen coupon? Baclofen is a widely used generic muscle relaxant, and because it is generic it is already one of the lower-cost prescriptions at most pharmacies. But the cash price still swings a lot from one pharmacy to the next, so it pays to compare before you fill. Enter your ZIP above to see today's price and a free Rx.com discount coupon you can use at the counter. Rx.com compares prices across more than 60,000 pharmacies so you can find the lowest cash price near you.

What is baclofen and how does it work?

Baclofen is a skeletal muscle relaxant, also called an antispastic agent. It works as a GABA-B receptor agonist in the spinal cord, calming the nerve signals that cause muscles to tighten and spasm. It is FDA-approved to treat spasticity — muscle spasm, clonus, cramping, tightness, and pain — that results from multiple sclerosis and from spinal cord injuries or diseases. Oral baclofen is used in patients 12 years and older.

Baclofen comes in several forms. The oral tablet is the common generic, and there are also branded oral options such as Ozobax and Ozobax DS (oral solution), Fleqsuvy (oral suspension), and Lyvispah (oral granules). A separate form, Gablofen, is given as an intrathecal injection through a surgically implanted pump for severe spasticity of spinal or cerebral origin, including cerebral palsy, when oral therapy fails or is not tolerated. The original brand Lioresal (oral) has been discontinued.

Baclofen cost and savings without insurance

Baclofen is available as an FDA-approved generic, which is why it is usually inexpensive compared with brand-name muscle relaxants. Even so, the cash price is not the same everywhere — different pharmacies can charge very different amounts for the exact same tablet, so comparing is the single best way to save. If you have no insurance, or your plan does not cover it well, a free discount coupon can often beat the standard shelf price.

The branded oral forms (Ozobax, Fleqsuvy, Lyvispah) generally cost more than the generic tablet. There is no manufacturer copay savings card for generic baclofen. To find the best price for your form and dose, enter your ZIP above to see today's price and print or show your Rx.com coupon at the pharmacy.

Baclofen vs. other muscle relaxants

Baclofen is one of several muscle relaxants your prescriber might consider, and each works a little differently. The closest comparison is tizanidine, which, like baclofen, is often used for spasticity but acts as an alpha-2 agonist and tends to be shorter-acting. Others are used mainly for short-term relief of muscle spasm from strains and injuries rather than for chronic spasticity.

  • Tizanidine — often used for spasticity; shorter-acting
  • Cyclobenzaprine — commonly used short-term for acute muscle spasm
  • Methocarbamol — used for short-term muscle spasm relief
  • Carisoprodol — a controlled substance used short-term for muscle spasm
  • Metaxalone — used short-term for muscle spasm, often chosen for lower sedation

All of these are generic, and prices vary by pharmacy, so it is worth comparing whichever one you are prescribed. Only your provider can decide which is right for you.

Baclofen safety and important warnings

Do not stop baclofen suddenly. For oral baclofen, stopping abruptly can trigger withdrawal — including seizures, hallucinations, and a rebound worsening of spasticity — so it should be tapered under your prescriber's guidance. Intrathecal baclofen (the implanted-pump form) carries an FDA boxed warning: abrupt loss of the drug, often from a pump or catheter malfunction, a dosing error, or a low reservoir, can cause life-threatening withdrawal with high fever, altered mental status, severe rebound spasticity and muscle rigidity, and rarely rhabdomyolysis, organ failure, and death.

Baclofen causes CNS depression — drowsiness, dizziness, sedation, and weakness — and these effects add up when combined with alcohol or other sedating medicines. Avoid driving until you know how it affects you. Use extra caution in older adults, in people with seizure disorders, and in those with kidney problems, since baclofen is cleared by the kidneys and may need a lower dose. Overdose can cause dangerous breathing problems and coma. This information is not medical advice — talk with your doctor or pharmacist about your full medication list and any conditions before starting or changing baclofen.

Sources & accuracy

This Baclofen information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Baclofen on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

¿Buscando esta página en español?

Related Drugs

Browse more medications: starting with B · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!

Rx.com does not warrant the accuracy of the information on this website. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of a drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug. All logos, brand names and trademarks on this website are the property of their respective owners. Rx.com is not endorsed or affiliated with any brands represented on this website."

Pharmacy discounts are Not Insurance, and are Not Intended as a Substitute for Insurance THE DISCOUNT IS ONLY AVAILABLE AT PARTICIPATING PHARMACIES As an Amazon Associate, we earn from qualifying purchases.

2026 All Rights Reserved | Rx.com®