Leqvio Coupons & Prices

Looking for a Leqvio coupon? Leqvio (inclisiran) is a brand-name, twice-yearly injection that lowers LDL ("bad") cholesterol in adults, and there is no generic version yet, which can make it expensive at the pharmacy. Rx.com offers a free cash-price coupon you can use to compare what pharmacies near you charge. Enter your ZIP above to see today's price, and read on to learn how the Rx.com cash coupon compares with the manufacturer's savings card.

What is Leqvio and how does it work?

Leqvio (inclisiran) is a cholesterol-lowering medicine given as a subcutaneous (under-the-skin) injection. It belongs to a class called PCSK9-directed small interfering RNA (siRNA) therapies. Instead of a pill you take every day, it works inside the liver to reduce the production of a protein (PCSK9), which helps your body clear more LDL cholesterol from the blood.

Leqvio is approved as an adjunct to diet and exercise to reduce LDL cholesterol in adults with hypercholesterolemia, in adults and children 12 and older with heterozygous familial hypercholesterolemia (HeFH), and in children 12 and older with homozygous familial hypercholesterolemia (HoFH). Per a July 2025 FDA label update, Leqvio can be used on its own (monotherapy) and no longer has to be added on top of a statin. A healthcare professional gives the injection initially, again at 3 months, and then every 6 months (twice a year).

Leqvio cost: manufacturer savings card vs. Rx.com cash coupon

Because Leqvio is brand-only with no generic, the price can be high. There are two main ways to save, and they work in different situations:

• Novartis manufacturer savings card: If you have commercial (private) insurance, you may qualify for the official Leqvio copay savings program. These cards are generally limited to people with commercial insurance and are typically not available if you are uninsured or have government coverage such as Medicare or Medicaid. Terms, eligibility, and any caps vary, so check the official page at leqvio.com/savings-and-support/savings.
• Rx.com cash coupon: Our free coupon is a cash-price discount, so it does not use your insurance. That makes it a useful backup if you are uninsured, have Medicare or Medicaid, or if the manufacturer card is declined. Enter your ZIP above to see today's price at pharmacies near you.

If cost is a barrier, it is also worth asking Novartis or your prescriber whether a patient assistance program is available for those who qualify.

Leqvio alternatives and related cholesterol medicines

Leqvio is one of several newer options for people who need more LDL-lowering than a statin alone provides. Others in the PCSK9 category are the injectables Repatha (evolocumab) and Praluent (alirocumab), which are given more often than Leqvio's twice-yearly schedule. Nexletol (bempedoic acid) is a once-daily oral option that works differently.

Each of these works and is dosed differently, and the right choice depends on your cholesterol goals, other medicines, and insurance. This is a decision to make with your provider, not something to switch on your own. You can compare current cash prices for each on Rx.com by entering your ZIP.

Leqvio safety and side effects

Leqvio has no boxed warning. The most common side effects reported in clinical trials (in at least 3% of people and more often than placebo) were injection-site reactions such as pain, redness, or rash, joint pain (arthralgia), and bronchitis. Hypersensitivity reactions, including some serious ones, have also been reported. Because Leqvio is given by a healthcare professional, they will handle the injection and monitor you.

Leqvio has not been studied in people with severe liver or severe kidney impairment, and there is limited information on its use during pregnancy or breastfeeding. This information is a summary and not medical advice. Talk with your doctor or pharmacist about whether Leqvio is right for you and about any side effects you notice.