Metolazone Coupons & Prices

Looking for a metolazone coupon? Metolazone is a widely available generic thiazide-like diuretic ("water pill") used to treat fluid retention (edema) and high blood pressure, so you almost never need a brand-name product to save. Even so, the cash price for the same tablets can vary a lot from one pharmacy to the next, which is exactly why comparing pays off. Enter your ZIP above to see today's price and free discount coupon accepted at more than 60,000 pharmacies nationwide.

What is metolazone and how does it work?

Metolazone is a thiazide-like (quinazoline) diuretic. It works on the kidneys to help your body get rid of extra salt and water through your urine, which reduces swelling and can lower blood pressure. It is FDA-approved to treat edema (fluid retention) linked to congestive heart failure and to kidney disease including the nephrotic syndrome, and to treat hypertension (high blood pressure), either on its own or with other blood-pressure medicines.

Metolazone is also very commonly used by doctors alongside a loop diuretic such as furosemide when a loop diuretic alone is not moving enough fluid. Combining the two blocks salt reabsorption at different points along the kidney (sometimes called sequential nephron blockade), which can produce a strong response in people whose swelling has stopped responding to a loop diuretic by itself.

How much does metolazone cost without insurance?

Metolazone is available as a generic, and generics are generally low-cost, so most people pay far less than they would for a brand-name diuretic. The former brands Zaroxolyn and Mykrox have both been discontinued in the U.S., which makes the generic the standard, affordable option. That said, the cash price is not the same everywhere. Different pharmacies set different prices for the very same tablets, so the amount you are quoted at one counter can be noticeably higher or lower than down the street.

Because prices move and vary by location, we show them live rather than list a figure here. Enter your ZIP above to see today's price at pharmacies near you and to pull up a free Rx.com discount coupon. Rx.com compares prices across more than 60,000 pharmacies, and the coupon is free to use whether or not you have insurance.

Metolazone compared with other diuretics

Metolazone is one of several diuretics your doctor may consider, and they are not interchangeable. Loop diuretics like furosemide and bumetanide are typically the workhorses for heart-failure fluid overload, while metolazone is often added to boost their effect. Other thiazide and thiazide-like options such as hydrochlorothiazide, chlorthalidone, and indapamide are more commonly first-line for high blood pressure. Spironolactone is a potassium-sparing diuretic that works differently and can help offset potassium loss.

Which one is right for you depends on your diagnosis, kidney function, and other medicines, so this is a conversation for your prescriber. Whatever you and your doctor land on, most of these are available as low-cost generics, and you can compare the price of each on Rx.com to see what fits your budget.

Safety and side effects

Metolazone has no boxed warning, but because it is an effective diuretic it can shift your body's fluids and salts. Possible effects include low potassium, low sodium, and low magnesium, dehydration, and dizziness or lightheadedness when standing up (orthostatic hypotension). These risks are greater when metolazone is combined with furosemide, because the two together can cause a strong loss of fluid. It may also raise uric acid (and trigger gout), blood sugar, and cholesterol in some people. Because of this, doctors usually check your electrolytes and kidney function with blood tests.

Tell your doctor if you have a sulfa (sulfonamide) allergy, since metolazone is related to sulfonamide drugs. It should not be used if you are not producing urine (anuria) or have severe liver problems (hepatic coma). It can also make your skin more sensitive to sunlight and, rarely, worsen lupus. One important note: products equivalent to the old Zaroxolyn are not automatically interchangeable, dose for dose, with the faster-acting Mykrox formulation. This is general information, not medical advice. Take metolazone exactly as prescribed and talk with your doctor or pharmacist about your own health and any side effects.