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Nifedipine Er Osmotic Release Tablet Extended Release 24 Hour — prescription drug image

Nifedipine Er Osmotic Release

NIFEdipine ER Osmotic Release 30MG

Prescriptions & Refills
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What is Nifedipine Er Osmotic Release?

Procardia XL is used in the treatment of hypertension and angina. Nifedipine is the generic version. On average Procardia XL costs about $491 for a supply of 30, 90 mg tablets, extended release. You can use our Rx.com savings offer to get an average Procardia XL discount of up to 80% off of the retail price at participating pharmacies near you.

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What is Nifedipine Er Osmotic Release ?

Procardia XL is used in the treatment of hypertension and angina. Nifedipine is the generic version. On average Procardia XL costs about $491 for a supply of 30, 90 mg tablets, extended release. You can use our Rx.com savings offer to get an average Procardia XL discount of up to 80% off of the retail price at participating pharmacies near you.
  • Fast, pounding, or uneven heartbeat
  • Stomach pain or bloating, nausea, vomiting, weight loss
  • Lightheadedness, dizziness, or fainting
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain that may spread, trouble breathing, nausea, unusual sweating, fainting
  • Blistering, peeling, red skin rash
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • This medicine may cause the following problems: Heart failureWorsening chest pain or increased risk of heart attackStomach or bowel blockage or ulcers
  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.
  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have stomach problems, heart failure, coronary artery disease, or recently had a heart attack.
What is nifedipine ER osmotic release used for?
It is FDA-approved to treat hypertension (high blood pressure) and to manage chronic stable (effort-related) angina and vasospastic (Prinzmetal's/variant) angina. As a once-daily osmotic-release tablet, it delivers nifedipine steadily over 24 hours.
What is the difference between nifedipine ER osmotic release and regular nifedipine?
Regular (immediate-release) nifedipine acts quickly and is usually taken several times a day, while the extended-release osmotic (GITS) tablet releases the drug slowly at a steady rate over about 24 hours, allowing once-daily dosing. They are not interchangeable, so take the exact form your prescriber ordered.
Why is there an empty tablet shell in my stool after taking nifedipine ER?
The osmotic tablet has a non-dissolving outer shell that pushes the medicine out slowly. After the drug is released, the empty, intact shell (sometimes called a ghost tablet) passes in the stool. This is expected and harmless, and it does not mean the medicine failed to work.
Can you cut or crush nifedipine extended-release osmotic tablets?
No. Do not crush, chew, or divide these tablets. Swallow them whole. Breaking the tablet can damage the controlled-release system and cause too much of the drug to be absorbed at once. If you have trouble swallowing tablets, talk to your prescriber or pharmacist.
What foods and drugs should you avoid while taking nifedipine ER?
Avoid grapefruit and grapefruit juice, which can increase nifedipine levels. Use caution with medicines that strongly inhibit or induce the CYP3A4 enzyme, since they can raise or lower drug levels. If you take a beta-blocker, it should be tapered gradually rather than stopped abruptly. Always review your full medication list with your doctor or pharmacist.
How much does Nifedipine Er Osmotic Release cost without insurance?
The price of Nifedipine Er Osmotic Release without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Nifedipine Er Osmotic Release?
Common side effects of Nifedipine Er Osmotic Release may include: Fast, pounding, or uneven heartbeat, Stomach pain or bloating, nausea, vomiting, weight loss, Lightheadedness, dizziness, or fainting, Rapid weight gain, swelling in your hands, ankles, or feet, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Nifedipine Er Osmotic Release?
Generic versions may be available for Nifedipine Er Osmotic Release. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Nifedipine Er Osmotic Release on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Nifedipine Er Osmotic Release?
The cheapest pharmacy for Nifedipine Er Osmotic Release depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Nifedipine Er Osmotic Release near you.

Nifedipine Er Osmotic Release Coupons & Prices

NIFEdipine ER Osmotic Release 30MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Nifedipine Er Osmotic Release Tablet Extended Release 24 Hour — prescription drug image
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Nifedipine Er Osmotic Release prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
30mg · Tablet Extended Release 24 Hour 30 $39.19 $10.22
60mg · Tablet Extended Release 24 Hour 30 $61.99 $13.50
90mg · Tablet Extended Release 24 Hour 30 $110.95 $16.97

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a nifedipine ER osmotic-release coupon? Nifedipine extended-release (the once-daily osmotic/GITS tablet, sold under the brand Procardia XL) is a low-cost generic used to treat high blood pressure and certain types of angina. Even so, the cash price can vary widely from one pharmacy to the next, which is why comparing before you fill matters. Enter your ZIP above to see today's price at pharmacies near you and get a free Rx.com discount coupon you can use at the register.

What is nifedipine ER osmotic-release and how does it work?

Nifedipine is a dihydropyridine calcium channel blocker. It relaxes and widens blood vessels, which lowers blood pressure and improves blood flow to the heart. The osmotic-release (GITS) version is an extended-release tablet designed to release nifedipine at a steady rate over a full 24 hours, so it is usually taken once a day. It is FDA-approved to treat hypertension (high blood pressure) and to manage chronic stable (effort-related) angina and vasospastic (Prinzmetal's/variant) angina.

The brand name for this once-daily osmotic tablet is Procardia XL. A related brand, Adalat CC, has been discontinued in the United States. This page is about the extended-release formulation; your prescriber and pharmacist can confirm which version your prescription is for.

Cost of nifedipine ER without insurance

Nifedipine extended-release is available as an FDA-approved generic, and generics are typically far less expensive than brand-name Procardia XL. That said, the cash price for the same tablet strength can differ a lot depending on which pharmacy you use, so it pays to compare rather than assume every pharmacy charges the same.

Rx.com compares prices across more than 60,000 pharmacies nationwide and provides a free discount coupon that can lower the cash price even if you do not have insurance, or when your plan does not cover the drug. Enter your ZIP above to see today's price near you. There is no manufacturer copay savings card for this generic; discount coupons like ours are the more common way to save.

Related medications and alternatives

Nifedipine belongs to the calcium channel blocker family. If you are comparing options, other medicines your prescriber might discuss include:

  • amlodipine — another once-daily dihydropyridine calcium channel blocker
  • felodipine — a dihydropyridine calcium channel blocker
  • diltiazem — a non-dihydropyridine calcium channel blocker
  • verapamil — a non-dihydropyridine calcium channel blocker
  • nifedipine — the immediate-release form of the same drug

These are not identical and are not interchangeable. Only your prescriber can decide which medication and formulation is right for you. Compare prices on any of them with Rx.com.

Safety and what to know before taking it

Common side effects can include dizziness, flushing, headache, and swelling in the ankles or feet (peripheral edema); some people experience low blood pressure. Rarely, angina or a heart attack can worsen when starting the drug or increasing the dose, especially in people with severe coronary artery disease. Nifedipine ER should not be used in cardiogenic shock, and it should be used with caution in people with liver problems or a history of gastrointestinal narrowing or strictures.

Do not crush, chew, or split the extended-release tablet; swallow it whole. Avoid grapefruit juice and other CYP3A4 inhibitors or inducers, which can raise or lower nifedipine levels. If you take a beta-blocker, it should be tapered gradually rather than stopped suddenly. This is general information, not medical advice, so review your medicines and any interactions with your doctor or pharmacist.

Sources & accuracy

This Nifedipine Er Osmotic Release information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Nifedipine Er Osmotic Release on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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