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Diltiazem Hcl Tablet — prescription drug image

Diltiazem Hcl

dilTIAZem HCl 30MG

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What is Diltiazem Hcl?

Diltiazem is a medication used to treat high blood pressure and control chest pain (angina). It helps relax blood vessels, making it easier for the heart to pump blood and increasing the supply of oxygen to the heart.

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What is Diltiazem Hcl ?

Diltiazem is a medication used to treat high blood pressure and control chest pain (angina). It helps relax blood vessels, making it easier for the heart to pump blood and increasing the supply of oxygen to the heart.

Source: MedlinePlus, U.S. National Library of Medicine

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Lightheadedness, dizziness, fainting
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Blistering, peeling, red skin rash
  • Slow, fast, pounding, or uneven heartbeat
  • Worsening chest pain, trouble breathing
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Do not stop using this medicine suddenly without asking your doctor, or you could develop life-threatening heart problems.
  • This medicine may make you dizzy, drowsy, or lightheaded. Stand or sit up slowly if you feel lightheaded or dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • This medicine may cause the following problems:Worsening heart failureLiver problemsSerious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart failure, heart rhythm problems, or stomach or bowel problems.
What is diltiazem used for?
Diltiazem is used to treat high blood pressure and chest pain (angina), including angina caused by coronary artery spasm. It is also very commonly used to slow and control the heart rate in atrial fibrillation, and the intravenous form is used in the hospital for certain fast heart rhythms such as atrial fibrillation, atrial flutter, and PSVT.
Is diltiazem a beta blocker or a calcium channel blocker?
Diltiazem is a calcium channel blocker, not a beta blocker. Specifically it is a nondihydropyridine (benzothiazepine) calcium channel blocker, which both relaxes blood vessels and slows the heart rate. Beta blockers such as metoprolol work through a different mechanism, though the two are sometimes confused because both can slow the heart.
What are the most common side effects of diltiazem?
The most common side effects include swelling in the ankles or feet, dizziness, and constipation. It can also slow the heart rate or lower blood pressure. Contact your provider about a very slow or irregular heartbeat, fainting, a new skin rash, or signs of liver problems.
Can you stop taking diltiazem suddenly?
No. You should not stop diltiazem abruptly, because doing so can worsen chest pain or heart problems. If you and your doctor decide to stop it, your provider will guide you on how to taper or adjust it safely.
What foods and drugs should you avoid while taking diltiazem?
Diltiazem has major interactions through the CYP3A4 pathway, including certain statins, some beta-blockers, and amiodarone, and combining it with a beta-blocker increases the risk of a very slow heartbeat or AV block. Grapefruit and grapefruit juice can raise diltiazem levels, so ask your pharmacist about them. Always give your provider a full list of your medications and supplements before starting diltiazem.
How much does Diltiazem Hcl cost without insurance?
The price of Diltiazem Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Diltiazem Hcl?
Common side effects of Diltiazem Hcl may include: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Lightheadedness, dizziness, fainting, Rapid weight gain, swelling in your hands, ankles, or feet, Blistering, peeling, red skin rash, Slow, fast, pounding, or uneven heartbeat. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Diltiazem Hcl?
Generic versions may be available for Diltiazem Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Diltiazem Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Diltiazem Hcl?
The cheapest pharmacy for Diltiazem Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Diltiazem Hcl near you.

Diltiazem Hcl Coupons & Prices

dilTIAZem HCl 30MG

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Diltiazem Hcl Tablet — prescription drug image
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Diltiazem Hcl prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
30mg · Tablet 90 $25.99 $13.50
60mg · Tablet 90 $34.49 $13.50
90mg · Tablet 90 $22.24 $19.44
120mg · Tablet 90 $176.89 $13.50

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a diltiazem HCl coupon? Diltiazem hydrochloride is a widely used generic heart medication, and because it is generic it is already one of the lower-cost options in its class. Even so, the cash price can vary a lot from one pharmacy to the next, so it pays to compare. Enter your ZIP above to see today's diltiazem price and a free Rx.com discount coupon accepted at more than 60,000 pharmacies nationwide.

What is diltiazem and how does it work?

Diltiazem hydrochloride is a calcium channel blocker in the nondihydropyridine (benzothiazepine) group. It relaxes blood vessels and slows the electrical signals that set your heart rate, which lowers blood pressure and eases the heart's workload. Extended-release and sustained-release oral forms are FDA-approved to treat high blood pressure (hypertension) and chronic stable angina, as well as angina caused by coronary artery spasm (Prinzmetal or variant angina).

Given intravenously in a hospital, diltiazem is approved for short-term rate control in atrial fibrillation or atrial flutter and to help convert paroxysmal supraventricular tachycardia (PSVT). It is also very commonly used to slow the heart rate in atrial fibrillation. It is sold under brand names including Cardizem, Cardizem CD, Cardizem LA, Cartia XT, Tiazac, Taztia XT, Dilt-XR, and Matzim LA.

Cost and savings: what diltiazem HCl runs without insurance

Diltiazem is available as an FDA-approved, substitutable generic, so it is generally affordable even if you pay cash without insurance. The catch is that pharmacies set their own cash prices, and the difference between the cheapest and most expensive pharmacy for the exact same prescription can be surprisingly large. That is why comparing before you fill matters.

Rx.com compares diltiazem prices across more than 60,000 pharmacies and shows you a free discount coupon you can use at the counter, with no insurance or membership required. There is no manufacturer copay savings card for generic diltiazem. Enter your ZIP above to see today's price near you and print or text yourself the coupon.

Diltiazem vs. related medications

Diltiazem's brand versions include Cardizem and long-acting products such as Cartia XT and Tiazac; the generic is substitutable for these. Another nondihydropyridine calcium channel blocker with similar heart-rate-slowing effects is verapamil.

Your prescriber may consider other options depending on whether the goal is blood pressure, angina, or heart-rate control. Amlodipine is a different (dihydropyridine) calcium channel blocker used mainly for blood pressure and angina, and metoprolol is a beta-blocker often used for rate control and other heart conditions. These are not interchangeable, so only change medications on your provider's advice.

Safety and side effects

Diltiazem has no boxed warning, but it can slow the heart too much, causing bradycardia, AV block, or low blood pressure. It should not be used in people with sick sinus syndrome or second- or third-degree AV block without a pacemaker, in a recent heart attack with fluid in the lungs, or in severe low blood pressure or cardiogenic shock. It is generally avoided in significant heart failure with a reduced ejection fraction because it can weaken the heart's pumping. Common side effects include swelling in the ankles or feet (peripheral edema), dizziness, and constipation; rarely it can cause serious skin reactions or raised liver enzymes.

Do not stop diltiazem suddenly, and swallow extended-release forms whole. It has major CYP3A4 drug interactions (for example certain statins, some beta-blockers, and amiodarone), and combining it with a beta-blocker raises the risk of a very slow heartbeat or AV block. This is general information, not medical advice, so review your full medication list with your doctor or pharmacist.

Sources & accuracy

This Diltiazem Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Diltiazem Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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