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Doxycycline Capsule Delayed Release — prescription drug image

Doxycycline

Oracea 40MG

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What is Doxycycline?

Oracea is an antibiotic used to treat rosacea or severe acne. The generic version of Oracea is doxycycline. The average price of Oracea is around $756 for a supply of 30, 40 mg capsules. Use our Rx.com savings offer to get great discounts on Oracea at participating pharmacies near you.

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What is Doxycycline ?

Oracea is an antibiotic used to treat rosacea or severe acne. The generic version of Oracea is doxycycline. The average price of Oracea is around $756 for a supply of 30, 40 mg capsules. Use our Rx.com savings offer to get great discounts on Oracea at participating pharmacies near you.
  • Diarrhea that may contain blood
  • Severe headache, dizziness, vision changes
  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches
  • Burning, pain, or irritation in your upper stomach or throat
  • Joint pain, unusual tiredness or weakness
  • Swollen, painful, or tender lymph glands in the neck, armpit, or groin, or yellow skin or eyes
  • Sudden and severe stomach pain, nausea, vomiting, lightheadedness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Birth control pills may not work as well when used together with this medicine. Use a second form of birth control to keep from getting pregnant.
  • Tell your doctor if you have kidney disease, liver disease, asthma, or an allergy to sulfites. Tell your doctor if you had surgery on your stomach, or if you have a history of yeast infections.
  • This medicine may cause the following problems:Permanent change in tooth color (in children younger than 8 years of age)Serious skin reactions, including exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS)Increased pressure inside the headYeast infectionImmune system problems
  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Oracea used for?
Oracea is FDA-approved to treat only the inflammatory lesions (the papules and pustules, meaning the bumps) of rosacea in adults. It has not been shown to help the redness, visible blood vessels, or eye-related symptoms of rosacea.
Is Oracea an antibiotic?
Oracea contains doxycycline, which belongs to the antibiotic tetracycline class, but at its low 40 mg dose it acts as an anti-inflammatory, not an antibiotic. This is a sub-antimicrobial dose, and Oracea is not indicated to treat or prevent bacterial infections and should not be used for that.
Is there a generic version of Oracea?
Yes. An FDA-approved generic, doxycycline 40 mg modified-release capsules, is available and is usually much less expensive than the brand. Ask your prescriber whether the generic is right for you, then enter your ZIP above to compare prices.
How much does Oracea cost with a savings card?
Your price depends on your pharmacy, insurance, and whether you use the brand or the generic. Galderma offers a manufacturer savings program that is generally limited to people with commercial insurance, with terms that vary. If you are uninsured, on Medicare, or the card is declined, a free Rx.com cash coupon may help. Enter your ZIP above to see today's price near you.
How long does it take for Oracea to work on rosacea?
Response times vary from person to person, so follow your prescriber's instructions and keep taking it as directed even if you do not see results right away. If you have questions about your progress or side effects, contact your doctor or pharmacist.
How much does Doxycycline cost without insurance?
The price of Doxycycline without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 47% off retail prices with a free Rx.com coupon.
What are the common side effects of Doxycycline?
Common side effects of Doxycycline may include: Diarrhea that may contain blood, Severe headache, dizziness, vision changes, Fever, chills, cough, runny or stuffy nose, sore throat, body aches, Burning, pain, or irritation in your upper stomach or throat, Joint pain, unusual tiredness or weakness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Doxycycline?
Generic versions may be available for Doxycycline. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Doxycycline on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Doxycycline?
The cheapest pharmacy for Doxycycline depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Doxycycline near you.

Doxycycline Coupons & Prices

Oracea 40MG

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Doxycycline Capsule Delayed Release — prescription drug image
Prescription
Doxycycline 40mg (30)
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Prescription weight loss

Weight-loss medication, prescribed online

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$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Doxycycline prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
40mg · Capsule 30 $1,326.27 $898.97

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for an Oracea coupon? Oracea is a brand-name, once-daily 40 mg doxycycline capsule prescribed to treat the inflammatory bumps (papules and pustules) of rosacea in adults. Whether you have commercial insurance, Medicare, or no coverage at all, you can use a free Rx.com cash coupon at the pharmacy counter. Enter your ZIP above to see today's price at pharmacies near you, and read on to compare your savings options and understand how this medicine works.

What is Oracea and how does it work?

Oracea is a modified-release form of doxycycline dosed at 40 mg (30 mg immediate-release plus 10 mg delayed-release beads). It is FDA-approved to treat only the inflammatory lesions (papules and pustules) of rosacea in adults. At this low, once-daily dose it works as an anti-inflammatory rather than as an antibiotic.

Two things are important to understand. First, 40 mg is a sub-antimicrobial (anti-inflammatory) dose, so Oracea is explicitly not indicated to treat or prevent bacterial infections and must not be used for that purpose. Second, it has not been shown to help the redness (erythema), visible blood vessels (telangiectasia), or eye-related (ocular) parts of rosacea, only the inflammatory bumps.

Oracea cost: manufacturer savings card vs. Rx.com cash coupon

The maker of Oracea, Galderma, offers an official patient savings program (you can find it by searching Galderma's Oracea site) that can lower the cost for some patients. Manufacturer copay cards like this are generally limited to people with commercial (non-government) insurance, and the terms, eligibility, and any limits vary and can change, so read the current program details carefully. These cards typically cannot be used if you are uninsured or covered by Medicare, Medicaid, or another federal program.

That is where the free Rx.com cash coupon fills the gap. It is a cash-price discount that anyone can use, no insurance required. It is useful if you are uninsured, on Medicare, or if the manufacturer card is declined at the pharmacy. You cannot combine a cash coupon with insurance on the same fill, but you can compare both and use whichever is lower. Enter your ZIP above to see today's price near you. Galderma also runs patient-assistance options for eligible patients who cannot afford their medication; ask your pharmacist or prescriber, or check Galderma's patient resources, to see whether you qualify.

Generic Oracea and related rosacea options

The biggest savings lever here is the generic. An FDA-approved generic of Oracea, doxycycline 40 mg modified-release capsules, is available and is usually far cheaper than the brand. Ask your prescriber to write for the generic when appropriate, and compare the generic cash price with your ZIP above. Note that ordinary doxycycline and doxycycline hyclate antibiotic products come in different (higher) doses and are not the same as this specific anti-inflammatory 40 mg formulation.

Rosacea is often managed with more than one medicine. Other prescription options your dermatologist may discuss include minocycline (another tetracycline-class oral option), and topical treatments such as Soolantra (ivermectin cream) and metronidazole gel or cream. The right choice depends on which features of your rosacea are most bothersome, so talk with your provider about what fits you.

Safety and side effects to know

Oracea is in the tetracycline class. Like other tetracyclines, it can cause permanent tooth discoloration, enamel problems, and a reversible slowing of bone growth if used during tooth development, so it should be avoided during the second and third trimesters of pregnancy, in infancy, and in children under 8. It can also make your skin more sensitive to sunlight (photosensitivity), so limit excessive sun and UV exposure and use sun protection.

Other reported risks include Clostridioides difficile-associated diarrhea, increased pressure around the brain (intracranial hypertension / pseudotumor cerebri, especially if taken with isotretinoin), and esophagus irritation or ulcers, so take it with plenty of fluid and stay upright afterward. Serious allergic reactions, including anaphylaxis, can occur. The most common side effects (reported in more than 2% of patients) are nasopharyngitis (cold-like symptoms), diarrhea, high blood pressure, and sinusitis. This is not a complete list and is not medical advice; talk with your doctor or pharmacist about your full history and any medications you take.

Sources & accuracy

This Doxycycline information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Doxycycline on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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