Doxycycline Hyclate
Doxycycline Hyclate 100MG
What is Doxycycline Hyclate?
Doxycycline Hyclate is an antibiotic used to treat infections caused by bacteria, as well as certain infections spread by ticks and other pests. It can also help prevent malaria and treat skin conditions like acne and rosacea.Side Effects
- Diarrhea that may contain blood
- Severe headache, dizziness, vision changes
- Fever, chills, cough, runny or stuffy nose, sore throat, body aches
Warnings
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Birth control pills may not work as well when used together with this medicine. Use a second form of birth control to keep from getting pregnant.
- Tell your doctor if you have kidney disease, liver disease, asthma, or an allergy to sulfites. Tell your doctor if you had surgery on your stomach, or if you have a history of yeast infections.
- This medicine may cause the following problems:Permanent change in tooth color (in children younger than 8 years of age)Serious skin reactions, including exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS)Increased pressure inside the headYeast infectionImmune system problems
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
Prescription savings · · · ·
What is Doxycycline Hyclate ?
Doxycycline Hyclate is an antibiotic used to treat infections caused by bacteria, as well as certain infections spread by ticks and other pests. It can also help prevent malaria and treat skin conditions like acne and rosacea.- Diarrhea that may contain blood
- Severe headache, dizziness, vision changes
- Fever, chills, cough, runny or stuffy nose, sore throat, body aches
- Burning, pain, or irritation in your upper stomach or throat
- Joint pain, unusual tiredness or weakness
- Swollen, painful, or tender lymph glands in the neck, armpit, or groin, or yellow skin or eyes
- Sudden and severe stomach pain, nausea, vomiting, lightheadedness
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blistering, peeling, red skin rash
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Birth control pills may not work as well when used together with this medicine. Use a second form of birth control to keep from getting pregnant.
- Tell your doctor if you have kidney disease, liver disease, asthma, or an allergy to sulfites. Tell your doctor if you had surgery on your stomach, or if you have a history of yeast infections.
- This medicine may cause the following problems:Permanent change in tooth color (in children younger than 8 years of age)Serious skin reactions, including exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS)Increased pressure inside the headYeast infectionImmune system problems
- This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
- This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Call your doctor if your symptoms do not improve or if they get worse.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Doxycycline Hyclate Coupons & Prices
Doxycycline Hyclate 100MG
Weight-loss medication, prescribed online
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Doxycycline Hyclate prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 50mg · Capsule | 14 | $28.99 | $5.84 |
| 100mg · Capsule | 14 | $29.29 | $10.65 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Looking for a doxycycline hyclate coupon? Doxycycline hyclate is a widely used generic tetracycline antibiotic, and because it is generic it is already one of the more affordable prescription antibiotics. Even so, the cash price can vary a great deal from one pharmacy to the next, so comparing before you fill can make a real difference. Rx.com compares live prices across more than 60,000 U.S. pharmacies so you can find the lowest price near you. Enter your ZIP above to see today's price and print or text a free discount coupon.
What is doxycycline hyclate and how does it work?
Doxycycline hyclate is a broad-spectrum antibiotic in the tetracycline class. It works by stopping bacteria from making the proteins they need to grow and multiply, which helps your body clear the infection. It is FDA-approved to treat a wide range of bacterial infections, including rickettsial infections (such as Rocky Mountain spotted fever, typhus, and Q fever), certain respiratory tract infections (including those caused by Mycoplasma pneumoniae), and several sexually transmitted infections such as chlamydia, nongonococcal urethritis, and lymphogranuloma venereum. It is also approved for inhalational anthrax after exposure, as an adjunct in severe acne and acute intestinal amebiasis, for certain eye and other specific bacterial infections, and for malaria prevention. It is often used as an alternative when penicillin cannot be given.
Doctors also commonly prescribe it for other conditions based on their clinical judgment. Doxycycline hyclate is sold under brand names including Vibramycin, Acticlate, Doryx, Vibra-Tabs, Morgidox, and Targadox, but the generic contains the same active ingredient.
Doxycycline hyclate cost and savings without insurance
Doxycycline hyclate is available as a generic (generic Vibramycin), which is why it is usually much cheaper than the brand-name versions. But "generic" does not always mean the same price everywhere. The cash price for the exact same prescription can differ widely between two pharmacies just a few miles apart, so it genuinely pays to compare before you fill.
If you are paying without insurance, or if a discount coupon beats your copay, Rx.com lets you compare live prices at more than 60,000 pharmacies and shows a free coupon you can use at the counter. Prices change often and depend on your ZIP code, the strength, and the quantity, so we do not quote a fixed dollar figure here. Enter your ZIP above to see today's price near you and get your coupon.
Comparing doxycycline hyclate with related options
Doxycycline comes in two common salt forms: hyclate and doxycycline monohydrate. Both deliver the same active drug, doxycycline, and are generally considered equivalent in effect; the main practical differences are cost and how each sits with some people's stomachs. You may also see the prescription written simply as doxycycline. The brand-name equivalent of the hyclate form is Vibramycin.
Other antibiotics your provider might consider for similar infections include minocycline (another tetracycline), amoxicillin (a penicillin), and azithromycin (a macrolide). Which one is right depends on the specific infection and your medical history, so this is a decision to make with your prescriber. Because prices and available forms differ, it is worth comparing each on Rx.com if your provider gives you a choice.
Important safety information
This is general information, not medical advice. Always follow your provider's and pharmacist's instructions. Doxycycline hyclate has no FDA boxed warning, but there are some important precautions. It should not be used during pregnancy or in children under 8 years old, because tetracyclines can permanently discolor developing teeth and slow bone growth. It can make your skin much more sensitive to sunlight, so protect yourself from excessive sun and UV exposure. To lower the risk of throat and esophageal irritation, take each dose with a full glass of water and do not lie down right afterward.
Doxycycline can also cause diarrhea related to Clostridioides difficile, which may appear up to two months after you finish the medicine, so report severe or watery diarrhea to your provider. Antacids, iron, calcium, and dairy products can reduce how much of the drug your body absorbs, so separate these from your dose. It may make hormonal birth control less effective, and in rare cases it can cause increased pressure around the brain (pseudotumor cerebri) or serious skin and hypersensitivity reactions. Contact your provider right away if you notice a bad reaction.
This Doxycycline Hyclate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Doxycycline Hyclate on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.