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Sulfacetamide Sodium (Acne) Bottle — prescription drug image

Sulfacetamide Sodium (Acne)

Sulfacetamide Sodium (Acne) 118ML of 10%

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What is Sulfacetamide Sodium (Acne)?

Klaron is indicated for the treatment of several bacterial skin infections including acne. Sulfacetamide Sodium Topical is the generic version of Klaron. The average Klaron price is about $350 for a supply of 118, 10% lotion. You can use our free Singlecare savings card to receive a Klaron discount of up to 80% at a local pharmacy that participates with Singlecare.

Prescription savings · · · ·

What is Sulfacetamide Sodium (Acne) ?

Klaron is indicated for the treatment of several bacterial skin infections including acne. Sulfacetamide Sodium Topical is the generic version of Klaron. The average Klaron price is about $350 for a supply of 118, 10% lotion. You can use our free Singlecare savings card to receive a Klaron discount of up to 80% at a local pharmacy that participates with Singlecare.
  • Redness
  • Dryness
  • Itching
  • Stinging at the application site
  • Avoid contact with eyes, mouth, and mucous membranes
  • If skin irritation or sensitivity develops, discontinue use and consult a healthcare provider
  • Not to be used for infections or injuries of the eye
  • May cause hypersensitivity reactions; seek immediate medical attention if signs of an allergic reaction appear
What is sulfacetamide sodium used to treat?
Topical sulfacetamide sodium is FDA-approved to treat acne vulgaris. In sulfur-combination formulations it is also widely used for acne rosacea and for seborrheic dermatitis of the skin and scalp. It comes as a lotion, cream, gel, cleanser or wash, foam, and medicated pads.
How long does it take for sodium sulfacetamide to work on acne?
Topical acne treatments generally take several weeks of consistent daily use before you see clear improvement, and results build gradually. Use it exactly as prescribed and do not stop early just because you do not see immediate change. If your acne has not improved after the time your provider expected, check back with them.
Can you use sulfacetamide sodium if you have a sulfa allergy?
No. Sulfacetamide sodium is a sulfonamide antibiotic and is contraindicated in anyone with a known hypersensitivity to sulfonamides ("sulfa" drugs) or to any component of the product. Tell your prescriber and pharmacist about any sulfa allergy before starting it.
Is sodium sulfacetamide an antibiotic?
Yes. Sodium sulfacetamide is a topical sulfonamide antibiotic. It works by inhibiting the growth of the bacteria associated with acne, Cutibacterium acnes (formerly Propionibacterium acnes).
What are the side effects of topical sulfacetamide?
The most common side effects are local skin reactions such as redness, itching, stinging, burning, dryness, and irritation where it is applied. Rarely, sulfonamides can cause serious hypersensitivity reactions, including Stevens-Johnson syndrome, so stop use and seek care at the first sign of a rash. It is for external use only and should be kept away from the eyes, lips, and mucous membranes.
How much does Sulfacetamide Sodium (Acne) cost without insurance?
The price of Sulfacetamide Sodium (Acne) without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Sulfacetamide Sodium (Acne)?
Common side effects of Sulfacetamide Sodium (Acne) may include: Redness, Dryness, Itching, Stinging at the application site. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Sulfacetamide Sodium (Acne)?
Generic versions may be available for Sulfacetamide Sodium (Acne). Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Sulfacetamide Sodium (Acne) on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Sulfacetamide Sodium (Acne)?
The cheapest pharmacy for Sulfacetamide Sodium (Acne) depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Sulfacetamide Sodium (Acne) near you.

Sulfacetamide Sodium (Acne) Coupons & Prices

Sulfacetamide Sodium (Acne) 118ML of 10%

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Sulfacetamide Sodium (Acne) Bottle — prescription drug image
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Looking for a sulfacetamide sodium coupon? Topical sulfacetamide sodium is a low-cost generic sulfonamide antibiotic used to treat acne, and because it has no brand-name monopoly the cash price is usually modest. Even so, what you pay can swing widely from one pharmacy to the next, so it pays to compare. Enter your ZIP code above to see today's price and print a free Rx.com discount coupon accepted at more than 60,000 U.S. pharmacies.

What is sulfacetamide sodium and how does it work?

Sulfacetamide sodium is a topical sulfonamide ("sulfa") antibiotic that is FDA-approved to treat acne vulgaris. It works by slowing the growth of the acne-associated bacteria Cutibacterium acnes (formerly called Propionibacterium acnes), which helps calm breakouts over time. It is sold under brand names such as Klaron, Ovace, Ovace Plus, and Seb-Prev, and it also appears in sulfur-combination products like Avar, Sumadan, Plexion, Rosula, and Clenia that are commonly used for acne rosacea and seborrheic dermatitis of the skin and scalp.

Available forms

Topical sulfacetamide sodium comes in several forms so you can match it to your skin and routine. Depending on the product, you may find it as a:

  • Lotion
  • Cream
  • Gel
  • Cleanser or wash
  • Foam
  • Medicated pads

Your prescriber or pharmacist can help you choose the form and strength that fits your skin type and where you are applying it. This is general information, not medical advice.

Cost without insurance and how to save

Sulfacetamide sodium is available as an FDA-approved generic, which usually keeps the cash price lower than a brand-only medication. That does not mean every pharmacy charges the same, though. Prices for the same tube or bottle can vary a lot between chains and neighborhoods, so comparing before you fill is the single easiest way to avoid overpaying, whether or not you use insurance.

Rx.com compares cash prices across more than 60,000 pharmacies and gives you a free discount coupon you can use instead of, or alongside, checking your insurance. There is no manufacturer copay savings card for generic sulfacetamide sodium. To see current pricing near you, enter your ZIP code above.

Alternatives and related acne treatments

Sulfacetamide sodium is one of several topical options for acne, and many people use it alongside or instead of other treatments their prescriber recommends. Related medications include topical antibiotics like clindamycin and erythromycin, the over-the-counter antibacterial benzoyl peroxide, the retinoids tretinoin and adapalene, and azelaic acid.

Each works differently, and the right choice depends on your skin, how severe your acne is, and how you tolerate side effects. Talk with your provider about which option or combination is best for you. You can compare prices on any of these with Rx.com by entering your ZIP code.

Safety and side effects

Sulfacetamide sodium should not be used by anyone with a known allergy to sulfonamides (a "sulfa" allergy) or to any ingredient in the product. The sulfur-combination cleansers should be avoided in people with kidney disease. Although it is applied to the skin, sulfonamides can rarely trigger serious body-wide reactions, including Stevens-Johnson syndrome and other severe hypersensitivity reactions. Stop using it and contact your provider right away at the first sign of a rash. There is no boxed warning on this medication.

The most common side effects are local and mild, such as redness, itching, stinging, burning, dryness, and irritation where you apply it. It is for external use only, so keep it away from your eyes, lips, and other mucous membranes. This is a summary, not medical advice, so read the label and ask your pharmacist or provider with any questions.

Sources & accuracy

This Sulfacetamide Sodium (Acne) information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Sulfacetamide Sodium (Acne) on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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