Cyclosporine Modified Coupons & Prices

Looking for a cyclosporine-modified coupon? Cyclosporine (modified) is the generic version of the brand-name immunosuppressants Neoral and Gengraf, and because it is available as a generic it is usually far less expensive than the brand. Even so, the cash price for the same strength and quantity can vary widely from one pharmacy to the next, so comparing before you fill can make a real difference. Rx.com compares prices across more than 60,000 pharmacies so you can find a low price near you and show a free discount coupon at the counter. Enter your ZIP above to see today's price for cyclosporine (modified).

What is cyclosporine (modified) and how does it work?

Cyclosporine (modified) is an immunosuppressant in a class of drugs called calcineurin inhibitors. It works by decreasing the activity of the immune system. It is used together with other medications to help prevent organ rejection in people who have received a kidney, liver, or heart transplant. It is also used alone or with methotrexate to treat rheumatoid arthritis when methotrexate alone has not helped, and to treat severe plaque psoriasis in patients who have not been helped by other therapies.

The word "modified" is important. The modified formulation (sold as Neoral and Gengraf) is absorbed more completely and more predictably than non-modified cyclosporine (Sandimmune). Because of that difference, the two forms are not interchangeable on a milligram-for-milligram basis and should not be swapped for one another without a physician's supervision and blood-level monitoring.

Cyclosporine (modified) cost and savings without insurance

Because cyclosporine (modified) is available as an FDA-approved generic, it is generally much cheaper than the Neoral or Gengraf brands. That said, the cash price is not the same everywhere. The price for an identical strength and quantity can differ significantly between a large chain and an independent or grocery pharmacy nearby, which is exactly why comparing pharmacies matters. Enter your ZIP above to see today's price and print or show a free Rx.com discount coupon at the pharmacy.

If your prescriber has you on the brand-name Neoral, the manufacturer (Novartis) offers a patient savings program through its official website, saveonmyprescription.com. Eligibility and terms vary and typically exclude government insurance, so check the program details directly. In many cases the generic cash price with an Rx.com coupon is the simplest way to save.

Related drugs and alternatives

Cyclosporine (modified) is the same active ingredient sold under the brands Neoral and Gengraf. It is distinct from non-modified Sandimmune, which is absorbed differently and is not substitutable without medical supervision. You may also see plain cyclosporine listed.

Other immunosuppressants a transplant team may use, alone or in combination, include:

• Tacrolimus — another calcineurin inhibitor
• Mycophenolate mofetil
• Sirolimus

Which medication is right depends on the transplanted organ or the condition being treated. Only your prescriber can decide whether one of these is appropriate for you; never switch on your own.

Important safety information

This is a brief summary and not medical advice; read the medication guide and talk with your provider. Cyclosporine (modified) carries FDA boxed warnings: it should only be prescribed by physicians experienced in immunosuppressive therapy and transplant management, and it should be given in facilities equipped to monitor patients. It increases the risk of serious or fatal infections and of malignancies, especially lymphoma and skin cancer. It can also raise blood pressure and cause dose-dependent kidney damage (nephrotoxicity). Because Neoral/Gengraf (modified) and Sandimmune (non-modified) are absorbed differently, they must not be substituted for one another without physician supervision and blood-level monitoring.

People taking it need regular blood pressure, kidney function, and cyclosporine blood-level checks. Patients treated for psoriasis or rheumatoid arthritis should avoid PUVA/UVB light therapy, methotrexate or other immunosuppressants, coal tar, and radiation because of increased skin cancer risk. Other risks include seizures and other nervous system effects, liver problems, and high potassium. Cyclosporine has many drug interactions: avoid grapefruit juice and St. John's wort, use caution with NSAIDs, statins, and sirolimus, and avoid live vaccines. Tell your provider about every medication and supplement you take.