Nitroglycerin Coupons & Prices

Looking for a nitroglycerin coupon? Nitroglycerin is a widely available generic nitrate used to treat and prevent angina (chest pain) in people with coronary artery disease. Because it is generic, it is already one of the lower-cost heart medicines, but the cash price still varies a lot from one pharmacy to the next and by form (sublingual tablets, spray, extended-release capsules, ointment, or patches). Enter your ZIP above to see today's price at pharmacies near you. Rx.com compares prices across 60,000+ pharmacies so you can find a low cash price without insurance.

What is nitroglycerin and how does it work?

Nitroglycerin is a nitrate vasodilator (an organic nitrate). It relaxes and widens blood vessels, which reduces the heart's workload and improves blood flow, easing the chest pain of angina in people with coronary artery disease. It comes in several forms for different purposes. Fast-acting sublingual tablets (such as Nitrostat and NitroQuick), sublingual or translingual sprays (such as Nitrolingual and NitroMist), and a sublingual powder (GoNitro, emptied from a single-dose 400 mcg packet under the tongue) are used at the first sign of an angina attack, or 5 to 10 minutes before activity that tends to trigger chest pain.

Longer-acting forms are used for ongoing prevention (prophylaxis): extended-release oral capsules (Nitro-Time), topical ointment (Nitro-Bid), and transdermal patches (Nitro-Dur, Minitran). In hospitals, intravenous nitroglycerin is used for situations such as perioperative high blood pressure, heart failure linked to a heart attack, and controlled blood-pressure lowering during surgery. A rectal ointment form (Rectiv 0.4%) is FDA-approved to treat moderate-to-severe pain from chronic anal fissures. Your prescriber will choose the form that fits your needs.

Nitroglycerin cost and savings without insurance

Nitroglycerin is available as a generic, which usually makes it far cheaper than a brand-name equivalent. Even so, the cash price is not the same everywhere, and it also depends on which form you are prescribed. That is exactly why comparing pharmacies matters: two stores in the same town can charge noticeably different amounts for the same prescription. There is no manufacturer copay savings card for generic nitroglycerin, so a discount-price comparison is typically the most reliable way to lower your out-of-pocket cost.

To see current pricing, enter your ZIP above and Rx.com will show today's price across 60,000+ pharmacies near you. You can use the Rx.com discount whether or not you have insurance; if you do have coverage, it is worth comparing the cash coupon price against your copay to see which is lower.

Related nitrates and alternatives

Nitroglycerin is one of several nitrate medicines used for angina. If you are comparing options or your prescriber has mentioned a different one, related drugs include Nitrostat (a brand of sublingual nitroglycerin tablet), Nitro-Dur (a nitroglycerin transdermal patch), isosorbide mononitrate, and isosorbide dinitrate. Ranolazine is a non-nitrate anti-anginal medicine that is sometimes used when nitrates alone are not enough.

Which medicine and form is right for you depends on whether you need fast relief of an attack, ongoing prevention, or both. This is a decision to make with your prescriber, not on your own.

Important safety information

This is general information, not medical advice; always follow your prescriber and pharmacist. The most important safety point: never combine nitroglycerin with PDE5 inhibitors for erectile dysfunction or pulmonary hypertension, including sildenafil, tadalafil, vardenafil, and avanafil, or with the drug riociguat. The combination can cause a severe, life-threatening drop in blood pressure. Common side effects include a throbbing headache, dizziness, flushing, and low blood pressure that can lead to fainting or a fast heartbeat.

Nitroglycerin can lose effectiveness if used continuously, so a daily nitrate-free interval is usually needed (for example, patches are often removed for 10 to 14 hours a day). Do not stop long-term nitrate therapy abruptly, as this can trigger rebound chest pain. Use extra caution if you have very low blood pressure, low blood volume, a right-sided heart attack, severe anemia, or increased pressure in the head. Nitroglycerin is not a controlled substance and does not carry a boxed warning. Talk with your doctor about your full medication list and health history.