Nitroglycerin is FDA-approved to treat and prevent angina (chest pain) in people with coronary artery disease. Fast-acting sublingual tablets, sprays, and a sublingual powder are used to stop or prevent an angina attack, while extended-release capsules, ointment, and patches are used for ongoing prevention. In hospitals, IV nitroglycerin is used for certain blood-pressure and heart-failure situations, and a rectal ointment form (Rectiv) is approved for pain from chronic anal fissures.

Sublingual nitroglycerin tablets, spray, and powder are fast-acting and are taken at the first sign of an angina attack, or about 5 to 10 minutes before activity that tends to bring on chest pain. If your chest pain does not improve after using it as directed, seek emergency care right away. Follow the exact dosing instructions your prescriber and the label give you.

Dosing is set by your prescriber and the product label, so follow their specific instructions rather than a general number. As a widely used guideline, if chest pain does not go away after taking your prescribed dose, doses are usually repeated only a limited number of times a few minutes apart, and you should call emergency services if the pain persists. Do not exceed the amount your doctor prescribes.

Viagra (sildenafil) and other PDE5 inhibitors such as tadalafil, vardenafil, and avanafil both lower blood pressure, as does nitroglycerin. Taking them together can cause a severe, life-threatening drop in blood pressure. The same danger applies to the drug riociguat. Because of this, nitroglycerin should never be combined with these medicines. Tell every prescriber about all the medications you take.

The most common side effects are a throbbing headache, dizziness, flushing, and low blood pressure that can cause fainting or a fast heartbeat. Many people find the headache eases over time. Contact your doctor if side effects are severe or do not improve, and do not stop long-term nitrate treatment suddenly without medical guidance.

Nitroglycerin is an antianginal agent that is prescribed to patients diagnosed with angina to treat their condition. Nitroglycerin is a generic drug. The average Nitroglycerin price is about $292 for a supply of 250 milliliters, 5 mg/mL intravenous solution. However, you can use our free Rx.com coupon card to save significantly on Nitroglycerin prices at a participating pharmacy near you.

The price of Nitroglycerin 25 Tablets Sublingual without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.

Common side effects of Nitroglycerin 25 Tablets Sublingual may include: Throbbing, severe, or ongoing headache, confusion, low fever, vision problems, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Blurred vision, Increased chest pain, fast or slow heartbeat, Trouble breathing, cold sweat, blue skin, lips, or nails. This is not a complete list — consult your pharmacist or doctor for full side effect information.

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