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Tetracycline Hcl

Tetracycline HCl 500MG

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What is Tetracycline Hcl?

Tetracycline is an antibiotic medication used to treat infections caused by bacteria, as well as certain infections spread by ticks, lice, and other animals. It is also effective in treating acne.

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What is Tetracycline Hcl ?

Tetracycline is an antibiotic medication used to treat infections caused by bacteria, as well as certain infections spread by ticks, lice, and other animals. It is also effective in treating acne.

Source: MedlinePlus, U.S. National Library of Medicine

  • Trouble swallowing
  • Yellow skin or eyes
  • Nausea, vomiting, loss of appetite, pain in the upper stomach
  • Unusual bleeding or bruising
  • Headache, blurred vision
  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Dark-colored urine or pale stools
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
  • Headache, blurred vision
  • Nausea, vomiting, loss of appetite, pain in the upper stomach
  • Trouble swallowing
  • Unusual bleeding or bruising
  • Yellow skin or eyes
  • Make sure your doctor knows if you have kidney disease or liver disease.
What is tetracycline used to treat?
Tetracycline is FDA-approved to treat a wide range of bacterial infections, including respiratory tract infections, infections caused by chlamydia, nongonococcal urethritis caused by Ureaplasma urealyticum, skin and soft tissue infections, rickettsial infections like Rocky Mountain spotted fever and typhus, relapsing fever caused by Borrelia, brucellosis, cholera, plague, and tularemia. It only treats bacterial infections and does not work against viruses like colds or the flu. Your provider decides whether it is appropriate for your specific infection.
Why can't children under 8 take tetracycline?
Tetracycline is contraindicated in children under 8 years old because it can cause permanent discoloration of developing teeth and may impair bone and growth development. For this same reason it is also avoided during pregnancy and breastfeeding. A provider will choose a different antibiotic for young children.
Can you take tetracycline with milk or dairy products?
It is best to avoid taking tetracycline with milk or dairy. The calcium in dairy binds to the drug and reduces how much your body absorbs, which can make it less effective. Antacids and supplements containing iron, calcium, magnesium, or zinc have the same effect. Follow the timing instructions from your pharmacist or the label so the antibiotic works as intended.
Does tetracycline make birth control less effective?
Tetracycline may reduce the effectiveness of hormonal contraceptives such as birth control pills. If you rely on hormonal birth control, ask your provider whether you should use an additional backup method while taking tetracycline and for a period afterward.
What foods and medications should you avoid while taking tetracycline?
Avoid taking tetracycline at the same time as dairy products, antacids, and supplements or medications containing iron, calcium, magnesium, or zinc, because they reduce how much of the drug your body absorbs. Also be aware that tetracycline can make hormonal birth control less effective and can increase sun sensitivity, so limit sun exposure and use protection. Never use outdated tetracycline. Give your provider and pharmacist a full list of your medications and supplements to check for interactions.
How much does Tetracycline Hcl cost without insurance?
The price of Tetracycline Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Tetracycline Hcl?
Common side effects of Tetracycline Hcl may include: Trouble swallowing, Yellow skin or eyes, Nausea, vomiting, loss of appetite, pain in the upper stomach, Unusual bleeding or bruising, Headache, blurred vision. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Tetracycline Hcl?
Generic versions may be available for Tetracycline Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Tetracycline Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Tetracycline Hcl?
The cheapest pharmacy for Tetracycline Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Tetracycline Hcl near you.

Tetracycline Hcl Coupons & Prices

Tetracycline HCl 500MG

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Tetracycline Hcl Capsule — prescription drug image
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Tetracycline Hcl 500mg (56)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a tetracycline HCl coupon? Tetracycline hydrochloride is a widely available generic broad-spectrum antibiotic, and because it is generic, cash prices are already low but can vary a lot from one pharmacy to the next. That price gap is exactly why comparing matters. Rx.com checks prices across 60,000+ pharmacies so you can find the lowest cash price near you. Enter your ZIP above to see today's price on tetracycline HCl, no insurance required.

What is tetracycline HCl and how does it work?

Tetracycline hydrochloride is a broad-spectrum, bacteriostatic antibiotic in the tetracycline class. It works by slowing the growth of susceptible bacteria, which gives your immune system time to clear the infection. It is FDA-approved to treat a range of bacterial infections, including upper and lower respiratory tract infections (such as those caused by Streptococcus pneumoniae and Haemophilus influenzae), infections caused by Chlamydia trachomatis, nongonococcal urethritis caused by Ureaplasma urealyticum, skin and soft tissue infections, rickettsial infections (such as Rocky Mountain spotted fever and typhus), relapsing fever caused by Borrelia, brucellosis, cholera, plague, and tularemia. It is only for bacterial infections that are proven or strongly suspected to be caused by susceptible bacteria.

The brand-name versions Sumycin, Achromycin V, and Panmycin have all been discontinued, so tetracycline HCl is available today only as a generic. Because there is no brand competing on the shelf, the generic is what you will fill, and prices are set pharmacy by pharmacy.

Tetracycline HCl cost and coupons without insurance

Tetracycline HCl is a long-established generic, so it is generally one of the more affordable antibiotics to pay for out of pocket. Even so, the cash price for the same prescription can differ widely between two pharmacies in the same town, which is why it pays to compare before you fill. You do not need insurance to use an Rx.com coupon, and in some cases a cash coupon price can beat an insurance copay.

Rx.com compares tetracycline HCl prices across more than 60,000 pharmacies to surface the lowest cash price near you. Enter your ZIP above to see today's price and pull up a free coupon you can show at the pharmacy counter. Prices change often, so the on-page price is always the number to trust.

Alternatives and related antibiotics

Tetracycline HCl belongs to the tetracycline family of antibiotics, and your prescriber may consider a related drug depending on the infection, dosing convenience, and how well you tolerate it. Newer tetracyclines like doxycycline and minocycline are often chosen for once- or twice-daily dosing and fewer food restrictions. Doxycycline hyclate is a common formulation of doxycycline. For some infections, an unrelated antibiotic such as amoxicillin may be a better fit.

Only your provider can decide which antibiotic is right for your infection. If you are prescribed one of these instead, you can compare its cash price on Rx.com the same way, by entering your ZIP.

Safety and important warnings

Tetracycline HCl has no boxed warning, but it carries important cautions. It should not be used in children under 8 years of age or during pregnancy or breastfeeding, because it can cause permanent tooth discoloration and may affect bone and growth development. It can make your skin much more sensitive to sunlight (exaggerated sunburn), and rarely can cause liver problems, increased pressure around the brain (pseudotumor cerebri), or C. difficile-associated diarrhea. Liver risk is higher with high doses, during pregnancy, or in people with kidney impairment, where the drug can build up. Never use outdated or degraded tetracycline, as it has been linked to a form of kidney damage.

Tetracycline may make hormonal birth control less effective, and its absorption is reduced by dairy, antacids, and supplements containing iron, calcium, magnesium, or zinc. This is general information, not medical advice. Tell your provider about all your medications and health conditions, and follow their guidance and the label on your prescription.

Sources & accuracy

This Tetracycline Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Tetracycline Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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