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Cefixime

Cefixime

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What is Cefixime?

Cefixime (Suprax) is a prescription cephalosporin antibiotic used to treat a variety of bacterial infections, including ear infections, strep throat, bronchitis, urinary tract infections (UTIs), and certain cases of gonorrhea. It works by stopping the growth of bacteria, helping clear the infection and relieve symptoms.

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What is Cefixime ?

Cefixime (Suprax) is a prescription cephalosporin antibiotic used to treat a variety of bacterial infections, including ear infections, strep throat, bronchitis, urinary tract infections (UTIs), and certain cases of gonorrhea. It works by stopping the growth of bacteria, helping clear the infection and relieve symptoms.

  • Blistering, peeling, red skin rash
  • Severe diarrhea, stomach cramps, fever
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bleeding problems, or phenylketonuria. Tell your doctor if you have an allergy to penicillins.
  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
What is cefixime used to treat?
Cefixime is FDA-approved to treat certain bacterial infections, including uncomplicated urinary tract infections, middle-ear infections (otitis media), throat infections such as pharyngitis and tonsillitis, and acute bronchitis or flare-ups of chronic bronchitis. It is also approved for uncomplicated gonorrhea, but the CDC now recommends it only as an alternative when the preferred treatment, ceftriaxone, is unavailable. It does not work against viral illnesses like colds or the flu.
Is cefixime a strong antibiotic?
Cefixime is a third-generation cephalosporin, a group of antibiotics that covers a broad range of bacteria, including some that older antibiotics cannot. Whether it is the right choice depends on the specific infection and the bacteria involved, not on being simply strong or weak. Your provider selects an antibiotic based on what is likely causing your infection and your medical history.
How long does it take for cefixime to work?
Many people start to feel better within a few days of starting cefixime, though the exact timing depends on the type and severity of the infection. It is important to keep taking it for the full course your provider prescribed, even if you feel well sooner, so the infection clears completely and does not come back. If you do not feel any better after several days, contact your provider.
Can you drink alcohol while taking cefixime?
Cefixime does not have a specific known interaction with alcohol the way some other antibiotics do. However, alcohol can worsen side effects such as nausea and stomach upset and may slow your recovery. It is best to limit or avoid alcohol while you are ill and taking any antibiotic, and to ask your pharmacist or provider about your particular situation.
Is cefixime the same as penicillin?
No. Cefixime is a cephalosporin, not a penicillin, though the two families are chemically related. Because of that relationship, people with a penicillin allergy can sometimes react to cephalosporins as well, so tell your provider about any penicillin or antibiotic allergy before taking cefixime. Cefixime should not be used by anyone with a known cephalosporin allergy.
How much does Cefixime 400MG cost without insurance?
The price of Cefixime 400MG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Cefixime 400MG?
Common side effects of Cefixime 400MG may include: Blistering, peeling, red skin rash, Severe diarrhea, stomach cramps, fever, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Cefixime 400MG?
Generic versions may be available for Cefixime 400MG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Cefixime 400MG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Cefixime 400MG?
The cheapest pharmacy for Cefixime 400MG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Cefixime 400MG near you.

Cefixime Coupons & Prices

Cefixime

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Cefixime Capsule — prescription drug image
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Looking for a cefixime coupon? Cefixime is the generic version of Suprax, a third-generation cephalosporin antibiotic doctors prescribe for certain bacterial infections. Because it is available as a generic, cefixime is usually one of the lower-cost antibiotic options, but the cash price still varies widely from one pharmacy to the next. Rx.com compares cefixime prices across more than 60,000 U.S. pharmacies so you can find the best deal near you. Enter your ZIP above to see today's price and print or show your free discount coupon at the pharmacy counter.

What is cefixime and how does it work?

Cefixime is a third-generation cephalosporin antibiotic, sold under the brand name Suprax. It works by interfering with the bacteria's ability to build their cell walls, which stops the bacteria from growing and helps your body clear the infection. It treats infections caused by susceptible bacteria only, so it will not help with colds, the flu, or other viral illnesses.

The U.S. Food and Drug Administration has approved cefixime for several bacterial infections, including uncomplicated urinary tract infections, otitis media (a middle-ear infection), pharyngitis and tonsillitis (throat infections), and acute bronchitis or flare-ups of chronic bronchitis. It is also approved for uncomplicated gonorrhea, though the CDC no longer recommends cefixime as a first-line treatment for gonorrhea because bacteria have become less susceptible to it; ceftriaxone is now preferred, and cefixime is used only when ceftriaxone is not available. Always take the full course exactly as your provider directs, even if you feel better early.

How much does cefixime cost without insurance?

Cefixime is available as an FDA-approved generic, so it is generally more affordable than the Suprax brand. Even so, the cash price without insurance can differ a lot depending on which pharmacy you use, your dose, and your location, which is exactly why comparing prices matters. Two pharmacies on the same street can charge noticeably different amounts for the identical prescription.

Rx.com compares cefixime prices across more than 60,000 pharmacies and gives you a free discount coupon you can use with or without insurance. There is no membership or signup required. Enter your ZIP code above to see today's price in your area, then bring the coupon to the pharmacy. If your prescriber wrote you the brand, ask whether the generic is right for you, since it typically costs less.

Cefixime alternatives and related antibiotics

Cefixime is one of several oral antibiotics used for common bacterial infections. Your provider chooses among them based on the type of infection, your allergy history, and local bacterial resistance patterns. Other cephalosporins in the same general family include cefdinir, cephalexin, cefuroxime, and cefpodoxime.

Depending on the infection, a doctor may instead prescribe a different class of antibiotic such as amoxicillin (a penicillin) or azithromycin (a macrolide). Only your prescriber can decide which antibiotic fits your situation, so do not substitute one for another on your own. Whichever one you are prescribed, you can compare its price on Rx.com to look for savings.

Cefixime safety and side effects

Cefixime has no boxed warning. It should not be used by anyone with a known allergy to cephalosporin antibiotics. If you have a penicillin allergy, tell your provider, because there is a risk of cross-reactivity and, rarely, serious allergic (anaphylactic) reactions. Like other antibiotics, cefixime can cause Clostridioides difficile-associated diarrhea, which is sometimes severe and can appear during treatment or even two or more months after you finish. People with reduced kidney function may need a lower dose, and cefixime may make hormonal birth control less effective. The chewable tablets contain phenylalanine (from aspartame), which matters for people with phenylketonuria.

The most common side effects are diarrhea, nausea, stomach pain, and indigestion. Contact your provider if diarrhea becomes severe or bloody, or if you notice signs of an allergic reaction such as rash, swelling, or trouble breathing. This information is not medical advice; talk with your doctor or pharmacist about your specific health history and any other medicines you take.

Sources & accuracy

This Cefixime information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Cefixime on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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