What is Cladribine ?

Cladribine is a synthetic antineoplastic agent used primarily for the treatment of hairy cell leukemia and other hematologic malignancies. It functions as an adenosine deaminase inhibitor, leading to the accumulation of toxic deoxyadenosine triphosphate metabolites in neoplastic cells, which results in cell death. Cladribine is administered through intravenous or subcutaneous routes, and its use requires careful monitoring of hematological and renal functions.

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blood in your urine or stools
• Fever or chills
• Unusual bleeding or bruising
• Pain, redness, or swelling at the IV site
• Trouble breathing
• Severe mouth sores
• Severe diarrhea

• This medicine can harm an unborn baby. Do not become pregnant or breastfeed while you are receiving this medicine. Tell your doctor if you are pregnant or breastfeeding before treatment begins.
• Tell your doctor if you have kidney or liver disease, kidney stones, gout, or any infections.
• You may get infections more easily while you are receiving this medicine. Stay away from crowds or anyone who has a cold, the flu, or other infection.
• Your doctor may prescribe medicine to prevent nausea and vomiting. Call your doctor if the medicine does not help.
• Severe diarrhea
• Severe mouth sores
• Trouble breathing
• Unusual bleeding or bruising