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Dupixent Pen — prescription drug image

Dupixent

Dupixent 2ML of 300MG/2ML

Prescriptions & Refills
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What is Dupixent?

Dupixent (dupilumab) is a prescription biologic injection used to treat several inflammatory conditions driven by overactive immune signaling, including moderate-to-severe atopic dermatitis (eczema), asthma (with an eosinophilic phenotype), chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, and prurigo nodularis. It is approved for adults and select pediatric populations. Dupixent is not a steroid — it is a targeted biologic that blocks specific interleukin (IL-4 and IL-13) signaling pathways that are overactivated in these allergic and inflammatory conditions. It is administered as a subcutaneous injection every two to four weeks depending on the condition and patient age. Access to Dupixent often requires prior authorization from insurance. A licensed provider can guide you through the approval process and determine if Dupixent is right for your condition. Use Rx.com to compare costs and explore savings options.

Prescription savings · · · ·

What is Dupixent ?

Dupixent (dupilumab) is a prescription biologic injection used to treat several inflammatory conditions driven by overactive immune signaling, including moderate-to-severe atopic dermatitis (eczema), asthma (with an eosinophilic phenotype), chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, and prurigo nodularis. It is approved for adults and select pediatric populations. Dupixent is not a steroid — it is a targeted biologic that blocks specific interleukin (IL-4 and IL-13) signaling pathways that are overactivated in these allergic and inflammatory conditions. It is administered as a subcutaneous injection every two to four weeks depending on the condition and patient age. Access to Dupixent often requires prior authorization from insurance. A licensed provider can guide you through the approval process and determine if Dupixent is right for your condition. Use Rx.com to compare costs and explore savings options.
  • Burning, dry, or itching eyes, discharge, excessive tearing
  • Fast heartbeat, trouble breathing, chest pain
  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches
  • Joint or muscle pain
  • Cold sores or blisters on lips, nose, eyes, or genitals
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Redness, pain, or swelling of the eye, eyelid, or inner lining of eyelid
  • Unusual tiredness or weakness
  • Blistering, peeling, redness, swelling, numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • This medicine may cause the following problems:Increased risk for eye infections, including conjunctivitis or keratitisJoint painEosinophilia, including pneumonia or vasculitis (swelling of the blood vessels)
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • This medicine will not stop an asthma attack that has already started. Your doctor may prescribe another medicine for you to use in case of an asthma attack. Tell your doctor right away if your symptoms do not improve or if they get worse.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have eye or vision problems, lung or breathing problems, heart problems, or a parasite infection.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
What is Dupixent used to treat?
Dupixent (dupilumab) is FDA-approved for a range of allergic and inflammatory conditions, including moderate-to-severe atopic dermatitis (eczema), add-on maintenance treatment of moderate-to-severe eosinophilic or oral-steroid-dependent asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, prurigo nodularis, COPD with an eosinophilic phenotype, chronic spontaneous urticaria, bullous pemphigoid, and allergic fungal rhinosinusitis. It is a maintenance medicine and is not used to treat a sudden asthma attack.
How much does Dupixent cost without insurance?
The cash price for Dupixent varies by pharmacy and location and changes over time, so we do not list a fixed dollar amount. Enter your ZIP code above to see today's price near you and get a free Rx.com discount coupon. Because Dupixent is a brand-only biologic with no generic, comparing pharmacy cash prices and using a coupon is often the main way to lower an out-of-pocket cost when you are uninsured.
Is there a generic version of Dupixent?
No. There is currently no generic or biosimilar version of Dupixent available. The active ingredient is dupilumab, but it is only sold under the brand name Dupixent, so there is no lower-cost generic to switch to. Comparing pharmacy prices and using a manufacturer savings card or an Rx.com cash coupon are the main ways to manage the cost.
What are the most common side effects of Dupixent?
The most commonly reported side effects include eye problems such as conjunctivitis and keratitis (especially in people treated for eczema), joint aches, and injection-site reactions. Less common but more serious risks include allergic reactions such as anaphylaxis and serum sickness, and rare eosinophilic conditions or vasculitis, most often when oral corticosteroids are being reduced. Do not stop steroids abruptly, and contact your provider about any concerning symptoms. This is a summary, not medical advice.
How is the Dupixent MyWay copay card different from regular insurance?
The Dupixent MyWay copay card is a manufacturer savings program, not insurance. It is generally available only to people with commercial (private) insurance and typically cannot be used if you are uninsured or covered by a government plan like Medicare or Medicaid. Its terms and any dollar limits are set by the manufacturer and can change, so check the official Dupixent MyWay page for current details. If you do not qualify for the card, an Rx.com cash coupon is a separate option that does not require insurance.
How much does Dupixent cost without insurance?
The price of Dupixent without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Dupixent?
Common side effects of Dupixent may include: Burning, dry, or itching eyes, discharge, excessive tearing, Fast heartbeat, trouble breathing, chest pain, Fever, chills, cough, runny or stuffy nose, sore throat, body aches, Joint or muscle pain, Cold sores or blisters on lips, nose, eyes, or genitals. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Dupixent?
Generic versions may be available for Dupixent. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Dupixent on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Dupixent?
The cheapest pharmacy for Dupixent depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Dupixent near you.

Dupixent Coupons & Prices

Dupixent 2ML of 300MG/2ML

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Dupixent Pen — prescription drug image
Prescription
Dupixent 2ml of 300mg/2ml (8)
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Looking for a Dupixent coupon? Dupixent (dupilumab) is a brand-only biologic injection with no generic available, so cash prices can be high. Rx.com shows you a live cash price at pharmacies near you and provides a free discount coupon you can use at the counter. Enter your ZIP above to see today's price on Dupixent, and read on to compare the Rx.com cash coupon with the manufacturer's Dupixent MyWay savings card.

What is Dupixent and how does it work?

Dupixent (dupilumab) is a monoclonal antibody biologic that blocks the interleukin-4 receptor alpha (IL-4/IL-13 signaling), which helps calm the type of inflammation behind several allergic and inflammatory conditions. It is FDA-approved for moderate-to-severe atopic dermatitis (eczema); as add-on maintenance treatment for moderate-to-severe eosinophilic or oral-steroid-dependent asthma; chronic rhinosinusitis with nasal polyps; eosinophilic esophagitis; prurigo nodularis; COPD with an eosinophilic phenotype; chronic spontaneous urticaria; bullous pemphigoid; and allergic fungal rhinosinusitis.

Dupixent is given as a subcutaneous (under-the-skin) injection every 1 to 4 weeks using a prefilled syringe or pen, depending on the condition being treated. It is a maintenance medicine, not a rescue treatment for a sudden asthma attack or acute bronchospasm.

Dupixent cost: manufacturer savings card vs. Rx.com cash coupon

Dupixent is a brand-name biologic with no generic version, so there is no lower-cost generic to switch to. That makes the price you pay depend heavily on your coverage. Two savings paths exist, and they work in different situations:

  • Dupixent MyWay savings card (manufacturer): The maker offers the Dupixent MyWay copay program, which is generally for people with commercial (private) insurance. It typically cannot be used if you are uninsured or covered by a government plan such as Medicare or Medicaid. Terms, eligibility, and any dollar limits are set by the manufacturer and can change, so check the official page for current details. Dupixent MyWay may also help eligible patients explore patient-assistance options if they cannot afford their medicine.
  • Rx.com cash coupon: Our free discount coupon is a cash-price option that does not require insurance. It can help if you are uninsured, if you have Medicare or another government plan that the manufacturer card excludes, or if the copay card is declined at the pharmacy. You cannot combine a discount coupon with insurance on the same purchase, so use whichever gives the better price that day.

Because prices vary by pharmacy and change over time, enter your ZIP above to see today's Dupixent price and coupon near you.

Dupixent alternatives and related biologics

Dupixent's active ingredient is dupilumab, and there is currently no generic or biosimilar substitute for it. If Dupixent is not the right fit, your prescriber may consider other biologics or targeted treatments depending on your specific condition. For asthma with an eosinophilic or allergic component, related biologics include Xolair, Nucala, and Fasenra. For atopic dermatitis (eczema), other options include Adbry as well as oral JAK inhibitors such as Cibinqo and Rinvoq.

These medicines are not interchangeable and are approved for different uses, so only your healthcare provider can decide which is appropriate for you. Whichever your provider prescribes, you can enter your ZIP above to compare cash prices and coupons for it on Rx.com.

Dupixent safety and side effects

Dupixent does not carry a boxed warning, but there are important safety points to know. The most commonly reported issues include eye problems such as conjunctivitis and keratitis (especially in people treated for eczema), joint aches (arthralgia), and injection-site reactions. More serious but less common risks include allergic (hypersensitivity) reactions such as anaphylaxis and serum sickness, higher eosinophil counts, and rare eosinophilic conditions or vasculitis (including signs consistent with EGPA) that have most often appeared when oral corticosteroids were reduced. Do not stop your oral or inhaled corticosteroids suddenly; any changes should be made gradually and under your prescriber's guidance.

Because Dupixent affects the immune response, tell your provider about any parasitic (helminth) infection before starting, avoid live vaccines during treatment, and report any signs of an allergic reaction right away. This information is a summary, not medical advice. Talk with your doctor or pharmacist about your full health history and any questions before starting or changing Dupixent.

Sources & accuracy

This Dupixent information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Dupixent on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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