What is Fenofibrate Micronized?

Fenofibrate Micronized is a lipid-modifying agent primarily used to reduce cholesterol levels, particularly triglycerides, and increase high-density lipoprotein (HDL) levels in patients with hypercholesterolemia or mixed dyslipidemia. It works by activating peroxisome proliferator-activated receptors (PPARs) which in turn enhance the oxidation of fatty acids and reduce the production of triglycerides in the liver. The micronized formulation allows for enhanced absorption and more consistent plasma levels, potentially improving therapeutic outcomes.

Side Effects

• Muscle pain, tenderness, or weakness
• Change in how much or how often you urinate
• Unusual bleeding, bruising, or weakness

Warnings

• Tell your doctor if you are pregnant, or if you have kidney disease, liver disease, heart disease, blood clotting problems, diabetes, or thyroid problems.
• Do not breastfeed during treatment and for at least 5 days after the last dose.
• This medicine may cause the following problems: Liver problemsSerious muscle problems (including myopathy), especially when used with other medicinesRhabdomyolysis (severe muscle weakness) that could lead to kidney damagePancreatitisIncreased risk of gallstonesSerious skin reactions, including Steven-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS)
• This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.