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Fluticasone Propionate Bottle — prescription drug image

Fluticasone Propionate

Fluticasone Propionate 16GM of 50MCG/ACT

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What is Fluticasone Propionate?

Fluticasone Propionate is a generic drug used to relieve allergies symptoms and treat certain skin conditions. The average Fluticasone Propionate price is about $55 for one 16 grams bottle of 50 mcg/inh nasal spray. You can use our Rx.com savings offer to get a Fluticasone Propionate discount of up to 80% at participating pharmacies near you.

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What is Fluticasone Propionate ?

Fluticasone Propionate is a generic drug used to relieve allergies symptoms and treat certain skin conditions. The average Fluticasone Propionate price is about $55 for one 16 grams bottle of 50 mcg/inh nasal spray. You can use our Rx.com savings offer to get a Fluticasone Propionate discount of up to 80% at participating pharmacies near you.
  • Bone pain
  • Eye pain or vision changes
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Sores or white patches inside the nose or mouth
  • Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
  • Heavy or unexplained bleeding from your nose, bleeding that will not stop
  • Burning, redness, swelling, or irritation around or inside your nose
  • Fever, chills, cough, sore throat, body aches
  • Tiredness, weakness, dizziness
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, asthma, any infection (including tuberculosis, herpes infection of the eye), a recent exposure to measles or chickenpox, or a history of cataracts, glaucoma, or osteoporosis. Tell your doctor if you have had nose surgery, a nose injury, or a recent infection in your nose.
  • This medicine may cause the following problems:Holes, ulcers, or bleeding inside the noseIncreased risk of infectionSlow wound healingCataracts or glaucomaProblems with the adrenal glandsLow bone mineral density, which may lead to osteoporosisSlow growth in children
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tiredness, weakness, dizziness
What is fluticasone propionate used for?
It depends on the form. The nasal spray treats sneezing and a runny, stuffy, or itchy nose from seasonal and year-round allergic and nonallergic rhinitis in adults and children 4 and older; the prescription Xhance spray treats chronic rhinosinusitis with or without nasal polyps. The fluticasone propionate inhaler (sold as an authorized generic since the Flovent HFA and Flovent Diskus brands were discontinued on January 1, 2024) is a maintenance treatment to help prevent asthma symptoms, not a rescue inhaler. The topical cream or ointment (Cutivate) relieves inflammation and itching from skin conditions such as eczema and psoriasis.
Is fluticasone propionate the same as Flonase?
Fluticasone propionate is the active ingredient in Flonase. A generic fluticasone propionate nasal spray is the store-brand equivalent of Flonase Allergy Relief and contains the same medicine. Flonase is one brand name; fluticasone propionate also appears in other products such as the asthma inhaler (formerly branded Flovent HFA and Flovent Diskus) and Cutivate skin creams. Note that Flonase Sensimist is a related but different medicine, fluticasone furoate.
Is fluticasone propionate a steroid?
Yes. Fluticasone propionate is a corticosteroid, which is a synthetic anti-inflammatory steroid (a glucocorticoid). It reduces inflammation in the area where it is used. It is not an anabolic steroid like the kind associated with bodybuilding.
What are the side effects of fluticasone propionate nasal spray?
Common local side effects of the nasal spray include nosebleeds and nasal irritation. Less often it can cause damage to the nasal septum, impaired wound healing, or a nasal yeast (Candida) infection. Long-term or high-dose corticosteroid use can also lead to body-wide effects such as adrenal suppression and eye problems. Contact your provider if you have ongoing nosebleeds or other bothersome symptoms.
Can you use fluticasone propionate every day?
Many people use fluticasone propionate nasal spray or inhaler daily as directed, since these work best with regular use over time. Follow your provider's or the product label's instructions on dose and how long to use it, because prolonged or high-dose corticosteroid use can raise the risk of side effects. Check with your doctor or pharmacist before starting daily use, especially for children or long-term treatment.
How much does Fluticasone Propionate cost without insurance?
The price of Fluticasone Propionate without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 49% off retail prices with a free Rx.com coupon.
What are the common side effects of Fluticasone Propionate?
Common side effects of Fluticasone Propionate may include: Bone pain, Eye pain or vision changes, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Sores or white patches inside the nose or mouth, Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Fluticasone Propionate?
Generic versions may be available for Fluticasone Propionate. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Fluticasone Propionate on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Fluticasone Propionate?
The cheapest pharmacy for Fluticasone Propionate depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Fluticasone Propionate near you.

Fluticasone Propionate Coupons & Prices

Fluticasone Propionate 16GM of 50MCG/ACT

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Fluticasone Propionate Bottle — prescription drug image
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Looking for a fluticasone propionate coupon? Fluticasone propionate is a widely used corticosteroid that comes as a nasal spray, an asthma inhaler, and a skin cream or ointment. It is available as a low-cost generic, but the cash price still varies a lot from one pharmacy to the next, so comparing pays off. Rx.com checks prices across more than 60,000 U.S. pharmacies so you can find the lowest price near you. Enter your ZIP above to see today's price on the strength and form your prescription calls for.

What is fluticasone propionate and how does it work?

Fluticasone propionate is a corticosteroid (a synthetic anti-inflammatory steroid). It works by calming inflammation in the tissue where it is applied, which reduces swelling, irritation, and allergy or asthma symptoms. Because it comes in several formulations, its FDA-approved uses depend on the form:

  • Nasal spray (over-the-counter and prescription): relieves nasal symptoms of seasonal and year-round allergic and nonallergic rhinitis, such as sneezing and a runny, stuffy, or itchy nose, in adults and children 4 years and older. Xhance is a prescription-only nasal spray that delivers a higher dose through an exhalation device and is approved for chronic rhinosinusitis with or without nasal polyps.
  • Inhaler (fluticasone propionate inhalation aerosol/powder, formerly sold as Flovent HFA / Flovent Diskus): maintenance treatment to help prevent asthma symptoms in patients 4 years and older. It is not a rescue inhaler and does not treat a sudden asthma attack or bronchospasm. GSK discontinued the Flovent HFA and Flovent Diskus brands in the U.S. effective January 1, 2024; the same medicine is now filled as an authorized generic (fluticasone propionate inhalation aerosol or inhalation powder), and an FDA-approved generic of the inhaler became available in March 2026.
  • Topical cream, ointment, or lotion (Cutivate): relieves the inflammation and itching of corticosteroid-responsive skin conditions such as eczema and psoriasis.

Fluticasone propionate cost and coupon savings

Fluticasone propionate is available as a generic, which is typically much less expensive than the brand-name versions. Even so, the cash price without insurance can differ widely between pharmacies in the same area, and it also depends on the formulation (nasal spray, inhaler, or topical) and the strength. That is exactly why comparing prices matters. Rx.com compares the cash price across more than 60,000 pharmacies and shows you a free discount coupon you can use at the counter, whether or not you have insurance. Enter your ZIP above to see today's price near you.

Some brand-name and prescription-only versions, such as Xhance, offer a manufacturer savings card. To find current details, search for the Xhance savings card on the manufacturer's official website. Eligibility and terms vary and are set by the manufacturer, so read them carefully.

Related drugs and alternatives

Fluticasone propionate is the same active ingredient found in Flonase, so a generic fluticasone propionate nasal spray is the store-brand equivalent of Flonase Allergy Relief. (Note that Flonase Sensimist is a different molecule, fluticasone furoate, not fluticasone propionate.) Other steroid nasal sprays your provider might discuss include mometasone, budesonide, and triamcinolone nasal. For added allergy relief, azelastine is an antihistamine nasal spray, and it is combined with fluticasone in some products.

Fluticasone is also paired with other medicines for the lungs. Fluticasone-salmeterol combines it with a long-acting bronchodilator, and Advair Diskus is a common brand of that combination. Your provider can help you choose the right formulation for your condition. You can compare prices on any of these using the ZIP search above.

Safety and side effects

Fluticasone propionate has no boxed warning, but general corticosteroid precautions apply. Local side effects depend on the form: the nasal spray can cause nosebleeds, nasal irritation, and, rarely, damage to the nasal septum or a nasal yeast (Candida) infection; the inhaler can cause oral thrush and a hoarse voice, which is why rinsing your mouth after each inhaler dose helps. With prolonged or high-dose use, corticosteroids can have body-wide effects such as adrenal suppression, slowed growth in children, lower bone density, and eye problems including glaucoma and cataracts.

Tell your provider about any active or past infections, including tuberculosis and eye herpes, since steroids can raise infection risk. Strong CYP3A4 inhibitors such as ritonavir and ketoconazole can increase the amount of fluticasone in your body and lead to steroid-related side effects. Remember that fluticasone is not a rescue treatment for a sudden asthma attack. This is general information, not medical advice, so talk with your doctor or pharmacist about your own situation and any drugs you take.

Sources & accuracy

This Fluticasone Propionate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Fluticasone Propionate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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