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Guanfacine Hcl Er Tablet Extended Release 24 Hour — prescription drug image

Guanfacine Hcl Er

guanFACINE HCl ER 1MG

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What is Guanfacine Hcl Er?

Guanfacine HCl ER is a medication used to help manage attention deficit hyperactivity disorder (ADHD). It works by affecting certain receptors in the brain to improve focus and reduce impulsive behavior. Your prescriber will determine the right dose for you.

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What is Guanfacine Hcl Er ?

Guanfacine HCl ER is a medication used to help manage attention deficit hyperactivity disorder (ADHD). It works by affecting certain receptors in the brain to improve focus and reduce impulsive behavior. Your prescriber will determine the right dose for you.

Source: MedlinePlus, U.S. National Library of Medicine

  • Lightheadedness, dizziness, or fainting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, trouble breathing
  • Fast, slow, or uneven heartbeat
  • Headache, confusion, tremors, nervousness
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Your doctor will also check your blood pressure and heart rate while you are using this medicine.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel problems, heart rhythm problems, or have had a recent heart attack or stroke.
  • This medicine may cause the following problems:Low blood pressureSlow heartbeatIncreased blood pressure and heart rate after suddenly stopping this medicine (rebound hypertension)
  • This medicine can make you dizzy, drowsy, or lightheaded, especially if you are dehydrated. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
Is guanfacine ER (Intuniv) the same as the generic for ADHD?
Yes. Guanfacine hydrochloride extended-release is the generic equivalent of the brand Intuniv, and both are FDA-approved to treat ADHD in children and adolescents ages 6 to 17. A generic is available and is generally a lower-cost option than the brand.
Is guanfacine a controlled substance or stimulant?
No. Guanfacine ER is a nonstimulant medication and is not a controlled substance. It works as a selective alpha-2A adrenergic receptor agonist rather than as a stimulant.
What is the difference between guanfacine ER and guanfacine immediate-release (Tenex)?
The extended-release form (brand Intuniv) is used to treat ADHD in children and adolescents, while immediate-release guanfacine (brand Tenex) is used for high blood pressure. The two are not interchangeable milligram-for-milligram, and the ER tablet must be swallowed whole, not crushed, chewed, or split.
Can adults take guanfacine ER for ADHD?
The FDA-approved indication for guanfacine ER is ADHD in children and adolescents ages 6 to 17. Use in adults is off-label, meaning it is not an FDA-approved use. Only a prescriber can decide whether it is appropriate for an adult.
What happens if you stop taking guanfacine ER suddenly?
Stopping guanfacine ER abruptly can cause rebound high blood pressure and an elevated heart rate. It should be tapered gradually under your provider's guidance rather than stopped all at once.
How much does Guanfacine Hcl Er cost without insurance?
The price of Guanfacine Hcl Er without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Guanfacine Hcl Er?
Common side effects of Guanfacine Hcl Er may include: Lightheadedness, dizziness, or fainting, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain, trouble breathing, Fast, slow, or uneven heartbeat, Headache, confusion, tremors, nervousness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Guanfacine Hcl Er?
Generic versions may be available for Guanfacine Hcl Er. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Guanfacine Hcl Er on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Guanfacine Hcl Er?
The cheapest pharmacy for Guanfacine Hcl Er depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Guanfacine Hcl Er near you.

Guanfacine Hcl Er Coupons & Prices

guanFACINE HCl ER 1MG

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Looking for a guanfacine HCl ER coupon? Guanfacine hydrochloride extended-release (the generic of Intuniv) is a nonstimulant medication FDA-approved to treat attention-deficit/hyperactivity disorder (ADHD) in children and adolescents ages 6 to 17. It is available as a lower-cost generic, but the cash price can vary widely from one pharmacy to the next, so comparing before you fill matters. Rx.com checks prices across more than 60,000 pharmacies. Enter your ZIP above to see today's price and print a free coupon.

What is guanfacine HCl ER and how does it work?

Guanfacine hydrochloride extended-release is a centrally acting selective alpha-2A adrenergic receptor agonist. Unlike stimulant ADHD medications, it is a nonstimulant. It is FDA-approved to treat ADHD in children and adolescents ages 6 to 17, either on its own or as an add-on (adjunctive) therapy to stimulant medications. It is meant to be part of a total treatment program that may include counseling and behavioral or educational support.

The extended-release tablet is designed to be swallowed whole once daily. It should not be crushed, chewed, or split, and it should not be taken with a high-fat meal, which can increase how much of the drug your body absorbs. This is not medical advice; talk with your provider about whether guanfacine ER is right for you or your child.

How much does generic guanfacine HCl ER cost without insurance?

Because guanfacine ER is available as a generic, it is generally an affordable option compared with the brand. Even so, the cash price without insurance is not the same everywhere. The same prescription can cost noticeably more at one pharmacy than at another across town, which is exactly why comparing pays off.

Rx.com compares guanfacine HCl ER prices across more than 60,000 pharmacies so you can find a lower cash price near you. Enter your ZIP above to see today's price and print or text yourself a free coupon to show the pharmacist. There is no insurance required to use the coupon.

Guanfacine ER vs. related medications

Guanfacine ER is one of several options for ADHD and related conditions. The branded version is Intuniv. The immediate-release form of the same drug, guanfacine (brand Tenex), is used to treat high blood pressure and is not interchangeable milligram-for-milligram with the extended-release tablet.

Other medications your provider may discuss include:

Only your prescriber can decide which medication fits your situation. You can compare cash prices for any of these on Rx.com.

Safety and important precautions

Guanfacine ER can lower blood pressure and heart rate in a dose-dependent way, which may cause dizziness, fainting (syncope), drowsiness, or sedation. Use caution with driving or operating machinery until you know how it affects you. It has no boxed warning and is not a controlled substance.

Do not stop guanfacine ER suddenly. Stopping abruptly can cause rebound high blood pressure and a rise in heart rate, so it should be tapered gradually under your provider's guidance. Use extra caution if you take other blood-pressure-lowering medicines, CNS depressants or alcohol, or strong CYP3A4 inhibitors or inducers, which may require a dose adjustment. The extended-release tablet must be swallowed whole and should not be substituted milligram-for-milligram with immediate-release guanfacine. This is general information, not medical advice; talk with your provider or pharmacist about your full list of medications.

Sources & accuracy

This Guanfacine Hcl Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Guanfacine Hcl Er on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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