Hydrocortisone Ace-Pramoxine
Hydrocortisone Ace-Pramoxine
What is Hydrocortisone Ace-Pramoxine?
Hydrocortisone Acetate-Pramoxine (Analpram Hc) is a prescription topical medication used to relieve the pain, itching, swelling, and irritation associated with hemorrhoids, anal fissures, and other inflammatory skin or rectal conditions. It combines a corticosteroid to reduce inflammation with a local anesthetic that provides fast pain and itch relief.
Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Weight gain around your neck, upper back, face, or waist
- Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
Warnings
- Tell your doctor if you are pregnant or breastfeeding.
- This medicine may cause adrenal gland problems. It may also cause you to get infections more easily, so tell your doctor if you have any type of infection.
- This medicine may delay growth in children. If you think your child is not growing properly while using this medicine, talk with your doctor.
- Call your doctor if your symptoms do not improve or if they get worse.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
Prescription savings · · · ·
What is Hydrocortisone Ace-Pramoxine ?
Hydrocortisone Acetate-Pramoxine (Analpram Hc) is a prescription topical medication used to relieve the pain, itching, swelling, and irritation associated with hemorrhoids, anal fissures, and other inflammatory skin or rectal conditions. It combines a corticosteroid to reduce inflammation with a local anesthetic that provides fast pain and itch relief.
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Weight gain around your neck, upper back, face, or waist
- Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
- Tell your doctor if you are pregnant or breastfeeding.
- This medicine may cause adrenal gland problems. It may also cause you to get infections more easily, so tell your doctor if you have any type of infection.
- This medicine may delay growth in children. If you think your child is not growing properly while using this medicine, talk with your doctor.
- Call your doctor if your symptoms do not improve or if they get worse.
- Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Hydrocortisone Ace-Pramoxine Coupons & Prices
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Looking for a hydrocortisone acetate and pramoxine coupon? Hydrocortisone acetate / pramoxine hydrochloride is a prescription combination medicine that pairs a topical corticosteroid (hydrocortisone acetate) with a numbing agent (pramoxine) to relieve itching, pain, and inflammation of the skin and of anorectal conditions like hemorrhoids. It is sold under brand names such as Analpram HC, Pramosone, and Proctofoam HC, and it is also available as a lower-cost FDA-approved generic. Because the cash price for the exact same product can vary widely from one pharmacy to another, comparing before you fill matters. Enter your ZIP code above to see today's price at pharmacies near you with a free Rx.com coupon.
What is hydrocortisone acetate / pramoxine and how does it work?
Hydrocortisone acetate / pramoxine hydrochloride is a prescription combination product that brings together two medicines that work in different ways. Hydrocortisone acetate is a topical corticosteroid that calms the skin's inflammatory response to reduce redness, swelling, and itching. Pramoxine hydrochloride is a local (topical) anesthetic that temporarily blocks the nerve signals responsible for pain and itch, so it provides a numbing, soothing effect.
It comes in several forms. The skin (topical) forms, including cream, lotion, ointment, and foam, are used to relieve the itching, inflammation, and discomfort of steroid-responsive skin conditions (dermatoses) such as eczema (atopic dermatitis), contact and allergic skin reactions, insect bites, and minor skin irritations. The rectal and anorectal forms, such as cream, foam, and suppositories, are used to treat the itching, pain, and inflammation of hemorrhoids and other inflammatory conditions of the anus and rectum, such as proctitis.
Hydrocortisone-pramoxine cost and how to save without insurance
Hydrocortisone acetate / pramoxine is available as an FDA-approved generic, so it is generally more affordable than the brand-name versions like Analpram HC, Pramosone, or Proctofoam HC. Even so, the cash price without insurance can vary a lot from one pharmacy to another for the very same medication, which is exactly why it pays to compare before you fill. There is no manufacturer copay savings card for this generic combination, so a free pharmacy discount coupon is usually the most reliable way to lower your out-of-pocket cost when you are paying cash.
Rx.com compares prices across more than 60,000 pharmacies so you can see today's cash price near you and print or show a coupon at the pharmacy counter. Enter your ZIP code above to see the current price at pharmacies in your area. You do not need insurance to use an Rx.com coupon, and it can sometimes beat an insurance copay, so it is worth comparing both.
Related products and alternatives
Hydrocortisone acetate / pramoxine is made from two active ingredients that are also available separately or in related products. Depending on whether you are treating a skin condition or an anorectal problem, and how your body responds, your prescriber or pharmacist may suggest a different form or a related option. It is worth comparing choices with them before you fill.
- Hydrocortisone - the topical corticosteroid on its own, without the added anesthetic.
- Pramoxine - the numbing (anesthetic) ingredient on its own, available in some over-the-counter anti-itch products.
- Hydrocortisone rectal - hydrocortisone in anorectal forms for hemorrhoid and rectal inflammation relief.
- Analpram HC - a brand version of the same hydrocortisone acetate / pramoxine combination.
- Pramosone - another brand of the same combination in topical forms.
- Proctofoam HC - a brand foam version used for anorectal conditions.
This is not medical advice. Only your prescriber can decide which ingredient, strength, and form is right for your condition.
Important safety information
Hydrocortisone acetate / pramoxine has no boxed warning, but it is intended for external, short-term use only. Do not apply it to broken skin, infected skin, or the face, underarms, or groin unless your provider specifically directs you to, and avoid getting it in your eyes. Using it over large areas of skin, under airtight (occlusive) dressings, for prolonged periods, or in children can allow enough of the steroid to be absorbed to cause effects on the body, including suppression of the HPA (hypothalamic-pituitary-adrenal) axis, Cushing syndrome, and high blood sugar. Local skin reactions can include thinning (atrophy), stretch marks, visible small blood vessels, burning, and folliculitis.
If irritation develops or your condition does not improve, stop using it and contact your provider. If you are using a rectal form and notice rectal bleeding, seek medical care. Use during pregnancy or while breastfeeding only if your provider tells you it is clearly needed. Talk with your doctor or pharmacist about your full medical history and any questions before starting treatment.
This Hydrocortisone Ace-Pramoxine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Hydrocortisone Ace-Pramoxine on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.