Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

Morphine Sulfate Er Tablet — prescription drug image

Morphine Sulfate Er

Morphine Sulfate ER 15MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes

What is Morphine Sulfate Er?

Morphine Sulfate ER (extended-release) is a potent opioid analgesic used for the management of persistent, moderate to severe pain that requires continuous, around-the-clock treatment. This formulation is designed to slowly release morphine over an extended period, providing prolonged pain relief while minimizing the need for frequent dosing. It is critical to use Morphic Sulfate ER strictly as prescribed, due to its high potential for addiction, abuse, and serious side effects.

Prescription savings · · · ·

What is Morphine Sulfate Er ?

Morphine Sulfate ER (extended-release) is a potent opioid analgesic used for the management of persistent, moderate to severe pain that requires continuous, around-the-clock treatment. This formulation is designed to slowly release morphine over an extended period, providing prolonged pain relief while minimizing the need for frequent dosing. It is critical to use Morphic Sulfate ER strictly as prescribed, due to its high potential for addiction, abuse, and serious side effects.
  • Severe confusion, lightheadedness, dizziness, fainting
  • Extreme dizziness or weakness, shallow breathing, slow or uneven heartbeat, sweating, cold or clammy skin, seizures
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there
  • Trouble breathing or slow breathing
  • Blue lips, fingernails, or skin
  • Severe constipation, stomach pain, or vomiting
  • This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, low blood pressure, breathing problems or lung disease (including asthma or COPD), gallbladder problems, pancreas problems, thyroid problems, an enlarged prostate, trouble urinating or swallowing, or stomach or bowel problems. Tell your doctor if you have a history of head injury, brain tumor, depression, seizures, or alcohol or drug abuse.
  • Do not breastfeed during treatment with this medicine.
  • This medicine may cause the following problems:Increased risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Serotonin syndrome (when used with certain medicines)Adrenal gland problemsLow blood pressureIncreased risk of seizures
  • This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Sit or lie down if you feel dizzy. Stand up carefully.
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.
What is morphine sulfate ER used for?
Morphine sulfate ER is used to manage moderate to severe pain that is severe enough to require daily, around-the-clock, long-term opioid treatment when other options, such as non-opioid pain relievers or immediate-release opioids, are not enough. It is commonly used for chronic cancer pain and other chronic pain needing continuous opioid therapy. It is not used for as-needed (prn) pain.
Is morphine sulfate ER a controlled substance?
Yes. Morphine sulfate ER is a Schedule II (C-II) controlled substance in the United States because of its high potential for abuse, misuse, and dependence. Schedule II prescriptions come with stricter rules, including limits on refills and transfers between pharmacies.
What is the difference between morphine sulfate ER and immediate-release morphine?
Extended-release (ER) morphine releases the medicine slowly over many hours to provide steady, around-the-clock pain control, so it is taken on a fixed schedule. Immediate-release morphine works quickly but wears off sooner and is often used for breakthrough or as-needed pain. ER tablets and capsules must be swallowed whole and are not interchangeable with immediate-release doses without your prescriber adjusting the plan.
Can you cut or crush morphine sulfate extended-release tablets?
No. Morphine sulfate ER tablets and capsules must be swallowed whole. Cutting, crushing, chewing, or dissolving them can release the entire long-acting dose at once, which can cause a fatal overdose. If you have trouble swallowing the medicine, talk to your doctor or pharmacist rather than altering the tablet.
What are the most common side effects of morphine sulfate ER?
Like other opioids, morphine sulfate ER can cause constipation, nausea, vomiting, drowsiness, dizziness, and sweating. More serious effects can include slowed or shallow breathing, severe low blood pressure, and excessive sedation, especially when combined with alcohol, benzodiazepines, or other sedating drugs. Contact your prescriber right away about severe or worrying symptoms, and seek emergency care for very slow or difficult breathing.
How much does Morphine Sulfate Er cost without insurance?
The price of Morphine Sulfate Er without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 92% off retail prices with a free Rx.com coupon.
What are the common side effects of Morphine Sulfate Er?
Common side effects of Morphine Sulfate Er may include: Severe confusion, lightheadedness, dizziness, fainting, Extreme dizziness or weakness, shallow breathing, slow or uneven heartbeat, sweating, cold or clammy skin, seizures, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there, Trouble breathing or slow breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Morphine Sulfate Er?
Generic versions may be available for Morphine Sulfate Er. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Morphine Sulfate Er on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Morphine Sulfate Er?
The cheapest pharmacy for Morphine Sulfate Er depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Morphine Sulfate Er near you.

Morphine Sulfate Er Coupons & Prices

Morphine Sulfate ER 15MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Morphine Sulfate Er Tablet — prescription drug image
Prescription
Morphine Sulfate Er 15mg (60)
your area ·
Prescription weight loss

Weight-loss medication, prescribed online

Licensed U.S. providers · No insurance needed · Shipped to your door

$146/mo vs. brand-name GLP-1 medications $1,300+/mo Save up to 88%
See if I qualify Free online visit · No commitment
Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Morphine Sulfate Er prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
15mg · Tablet 60 $96.99 $24.65
30mg · Tablet 60 $154.99 $32.24
60mg · Tablet 60 $253.99 $42.47
100mg · Tablet 60 $414.99 $41.54
200mg · Tablet 60 $704.69 $76.50

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a morphine sulfate ER coupon? Morphine sulfate extended-release is the generic form of long-acting morphine, sold under brands like MS Contin and Kadian. Because FDA-approved generic versions are widely available, it is already lower-cost than the brand versions, but the cash price can still swing widely from one pharmacy to the next. Enter your ZIP above to see today's price and compare a free Rx.com discount across more than 60,000 pharmacies near you before you fill.

What is morphine sulfate ER and how does it work?

Morphine sulfate ER (extended-release) is an opioid agonist analgesic that works at the mu-opioid receptors in the brain and spinal cord to change how the body senses and responds to pain. The "ER" means the medicine is released slowly over many hours, so a single dose provides continuous, around-the-clock relief rather than the quick, short-lived effect of an immediate-release tablet.

It is prescribed for moderate to severe pain that is bad enough to require daily, long-term opioid treatment when other options, such as non-opioid pain relievers or immediate-release opioids, are not enough. It is often used for chronic cancer pain and other ongoing pain that needs continuous therapy. It is not meant for as-needed (prn) pain. Because of the risks of addiction, abuse, misuse, and life-threatening breathing problems, it is reserved for patients for whom other treatments are ineffective, not tolerated, or otherwise inadequate.

Morphine sulfate ER cost and savings without insurance

Morphine sulfate ER is available as an FDA-approved generic, which usually makes it far less expensive than the brand-name versions. Even so, the cash price is not the same everywhere. Two pharmacies on the same street can quote very different prices for the identical tablet and strength, which is exactly why comparing before you fill matters.

Rx.com lets you compare the cash price and a free discount at more than 60,000 pharmacies, so you can see which nearby location is lowest today. There is no manufacturer copay or savings card for generic morphine sulfate ER, so the Rx.com discount is a straightforward way to help lower an out-of-pocket cost if you are paying without insurance or your plan does not cover it. Enter your ZIP above to see today's price. Because this is a Schedule II controlled substance, prescriptions cannot be refilled or transferred like other medicines, so it helps to know your best pharmacy option in advance.

Related long-acting opioids and brand equivalents

Morphine sulfate ER is the generic behind several brands. If your prescription is written for a specific brand, you can compare it directly: MS Contin and Kadian are both long-acting morphine products. Your prescriber may also consider other extended-release opioids depending on your situation.

  • Morphine sulfate (immediate-release) for shorter-acting dosing
  • Oxycodone ER and OxyContin
  • Hydromorphone ER
  • Fentanyl patch
  • Tramadol ER

These are not interchangeable, and switching between opioids requires careful dose conversion by your prescriber. Never change or combine opioids on your own. Use the search above to compare prices on whichever one you are prescribed.

Important safety information

Morphine sulfate ER is a Schedule II controlled substance and carries an FDA Boxed Warning. It can lead to addiction, abuse, and misuse, which can result in overdose and death, and it can cause serious, life-threatening, or fatal slowed breathing (respiratory depression), especially when you first start it or after a dose increase. Tablets and capsules must be swallowed whole; crushing, chewing, or dissolving them can release a fatal dose all at once. Accidental swallowing, especially by a child, can be fatal, so store it securely. Prolonged use during pregnancy can cause neonatal opioid withdrawal syndrome, which can be life-threatening if not treated.

Combining morphine ER with benzodiazepines, alcohol, or other central nervous system depressants can cause extreme, potentially fatal sedation and breathing problems. Morphine is cleared mainly through glucuronidation in the liver rather than the CYP450 enzymes, so its most significant interactions are with other CNS depressants and with serotonergic medicines, which can raise the risk of serotonin syndrome, along with certain other drugs your prescriber and pharmacist will review. Other risks include adrenal insufficiency, severe low blood pressure, and added danger in people with head injury or increased pressure in the skull. Extended-release/long-acting opioids are subject to an FDA REMS program. This is not medical advice. Talk with your doctor or pharmacist about your full list of medicines and any questions before starting or stopping this medication.

Sources & accuracy

This Morphine Sulfate Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Morphine Sulfate Er on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

Sponsored
Sesame Care — 350+ medications for $1 without insurance
¿Buscando esta página en español?

Related Drugs

Browse more medications: starting with M · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!

Rx.com does not warrant the accuracy of the information on this website. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of a drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug. All logos, brand names and trademarks on this website are the property of their respective owners. Rx.com is not endorsed or affiliated with any brands represented on this website."

Pharmacy discounts are Not Insurance, and are Not Intended as a Substitute for Insurance THE DISCOUNT IS ONLY AVAILABLE AT PARTICIPATING PHARMACIES As an Amazon Associate, we earn from qualifying purchases.

2026 All Rights Reserved | Rx.com®