Natazia
Natazia
What is Natazia?
Natazia is a prescription birth control pill used to help prevent pregnancy and treat heavy menstrual bleeding in certain women. Compare Natazia cost, find a Natazia coupon, and save on your prescription with the free Rx.com Prescription Discount Card.
Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain, trouble breathing, or coughing up blood
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Warnings
- You may need to stop using this medicine for a few weeks before and after you have surgery because of the risk of blood clots.
- This medicine may make your periods lighter or shorter, and you might not have a period in some cycles. However, tell your doctor if you miss 2 periods in a row, or if you miss 1 period and did not take the pills on schedule during the month. You might be pregnant.
- This medicine will not protect you from HIV/AIDS or other sexually transmitted diseases.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Prescription savings · · · ·
What is Natazia ?
Natazia is a prescription birth control pill used to help prevent pregnancy and treat heavy menstrual bleeding in certain women. Compare Natazia cost, find a Natazia coupon, and save on your prescription with the free Rx.com Prescription Discount Card.
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain, trouble breathing, or coughing up blood
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Double vision or other trouble seeing
- New or unusual headaches
- Unusual or unexpected vaginal bleeding or heavy bleeding
- Pain in your lower leg (calf)
- Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
- You may need to stop using this medicine for a few weeks before and after you have surgery because of the risk of blood clots.
- This medicine may make your periods lighter or shorter, and you might not have a period in some cycles. However, tell your doctor if you miss 2 periods in a row, or if you miss 1 period and did not take the pills on schedule during the month. You might be pregnant.
- This medicine will not protect you from HIV/AIDS or other sexually transmitted diseases.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- This medicine may cause the following problems:Higher risk of heart attack, stroke, or blood clotsPossible risk of breast or cervical cancerLiver cancers or tumorsHigh blood pressureGallbladder disease
- Tell your doctor if you have cancer, diabetes, blood circulation problems, or migraine headaches, or if you smoke. Tell your doctor if you are breastfeeding, or if you have recently given birth. Also tell your doctor if you have kidney disease, high blood pressure, gallbladder disease, high cholesterol, or a history of depression, angioedema, or jaundice.
- Tell your doctor right away if you think you are pregnant or if you miss your period 2 months in a row, because you could be pregnant.
Natazia Coupons & Prices
Natazia
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a Natazia coupon? Natazia is a brand-name combination birth control pill (estradiol valerate and dienogest) with no generic version yet available, so cash prices can run high. Rx.com offers a free cash coupon you can use at the pharmacy counter whether or not you have insurance. Enter your ZIP above to see today's price at pharmacies near you, then bring the coupon to save on your prescription.
What is Natazia and how does it work?
Natazia is a combination oral contraceptive that pairs two hormones, estradiol valerate (a form of estrogen) and dienogest (a progestin). Unlike most birth control pills, it is a four-phasic (quadriphasic) pill, meaning the hormone doses change across four stages of the cycle. It is FDA-approved to prevent pregnancy in women who choose an oral contraceptive for birth control, and it is also the first oral contraceptive FDA-approved to treat heavy menstrual bleeding that is not caused by a diagnosed uterine condition, in women who also want the Pill for contraception.
For heavy menstrual bleeding, the steady combination of estrogen and progestin helps stabilize and thin the uterine lining, which reduces the amount of menstrual blood loss over time. Its efficacy has not been studied in women with a BMI greater than 30 kg/m2. Natazia does not protect against HIV or other sexually transmitted infections.
Natazia manufacturer savings card vs. Rx.com cash coupon
The maker of Natazia offers a manufacturer savings card, and you can review its current terms on the official site at natazia.com. Manufacturer copay cards like this are generally limited to people with commercial (private) insurance and typically exclude anyone covered by Medicare, Medicaid, or other government programs. Terms, eligibility, and any dollar limits vary and change over time, so check the official page for the latest details.
The Rx.com cash coupon works differently: it is a cash-price discount, so it can help if you are uninsured, are on Medicare or another government plan that the manufacturer card excludes, or if the savings card is declined at the counter. You cannot combine a cash coupon with insurance on the same fill, but you can compare both and use whichever is lower. Because there is no generic for Natazia yet, the brand price is what you are comparing. Enter your ZIP above to see today's Rx.com price near you.
Natazia alternatives and related birth control pills
Natazia is one of several combination birth control pills, and the right choice depends on your health history and what your prescriber recommends. Other combination pills people compare with Natazia include Yaz, Yasmin, Beyaz, Loryna, and Lo Loestrin Fe. If you cannot take estrogen, a progestin-only option such as Slynd may be discussed with your provider.
Several of these alternatives have lower-cost generic versions available, which can be a significant savings lever compared with a brand-only pill like Natazia. Only your prescriber can decide whether switching is appropriate for you, so use this list as a starting point for that conversation rather than a recommendation to change on your own.
Natazia safety and warnings
Natazia carries a boxed warning: women older than 35 who smoke should not use it, because smoking combined with estrogen-containing birth control pills significantly raises the risk of serious cardiovascular events such as heart attack, stroke, and blood clots. Like other combination pills, Natazia can increase the risk of venous and arterial blood clots, and that risk is higher when other risk factors are present.
Other risks include liver disease or liver tumors, high blood pressure, gallbladder disease, and changes in how your body handles blood sugar and fats. Natazia should not be used during pregnancy. This information is a summary, not medical advice, and does not cover every risk. Talk with your doctor or pharmacist about your personal health history and report any concerning symptoms right away.
This Natazia information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Natazia on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.