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Nicotine

Nicotine 14 Patch 24 Hour

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What is Nicotine?

Nicotine is a cessation agent that is used to treat nicotine withdrawal. Nicotine is a generic drug. The average Nicotine price is about $15 for a supply of 20, 2 mg oral transmucosal gum. However, you can use our free Rx.com coupon card to save significantly on Nicotine rices at a participating pharmacy near you.

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What is Nicotine ?

Nicotine is a cessation agent that is used to treat nicotine withdrawal. Nicotine is a generic drug. The average Nicotine price is about $15 for a supply of 20, 2 mg oral transmucosal gum. However, you can use our free Rx.com coupon card to save significantly on Nicotine rices at a participating pharmacy near you.
  • Fast, slow, pounding, or uneven heartbeat
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dizziness, headache, upset stomach, drooling, vomiting, diarrhea, cold sweats, blurred vision, trouble hearing, confusion, fainting, or weakness
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • The opaque NicoDerm® CQ patch may cause skin burns if you have a procedure called a magnetic resonance imaging (MRI) scan. You must remove the patch before an MRI.
  • Pregnant or breastfeeding women should only use this medicine as directed by a doctor. Smoking can seriously harm your unborn child. Try to stop smoking without using medicine. Although this medicine is believed to be safer than smoking, the risks of its use during pregnancy are not fully known.
  • Tell your doctor if you have heart disease, heart rhythm problems, high blood pressure, or you had a recent heart attack. Tell your doctor if you have an allergy to adhesive tape.
  • This medicine may cause the following problems:High blood pressureIncrease in heart rate
Is nicotine replacement therapy safe?
For most people trying to quit smoking, nicotine replacement therapy is considered a safe and effective option, and it has no boxed warning. Use caution if you have had a recent heart attack, serious or worsening irregular heartbeats, or severe or worsening chest pain, since nicotine can raise heart rate and blood pressure. Discuss use in pregnancy or breastfeeding with your clinician. Keep products, including used patches and gum, away from children and pets, because nicotine is highly toxic if swallowed. This is general information, not medical advice.
Can you use the nicotine patch and nicotine gum at the same time?
Yes. Using a long-acting patch together with a fast-acting gum, lozenge, or spray is called combination therapy, and research shows it works better than a single product alone. The patch provides steady background coverage while the gum handles sudden cravings. It is a good idea to review your plan with a provider or pharmacist to get the dosing right.
How long should you use nicotine replacement therapy?
NRT is typically used for a set course of weeks while you break the smoking habit, following the schedule on the product package or the plan your provider gives you. The goal is to gradually reduce and then stop nicotine use. If you are still relying on it after the recommended period, or want to taper differently, talk with your provider or pharmacist for guidance.
Is nicotine gum available over the counter or do you need a prescription?
Nicotine gum, along with the patch and lozenge, is available over the counter without a prescription. The nasal spray form (Nicotrol NS) is a prescription product. Even for OTC forms, prices vary by pharmacy, so it can pay to compare with a coupon, and some items may cost less when prescribed.
What are the side effects of nicotine patches and gum?
The patch most often causes skin irritation where it is worn. Gum and lozenges can cause mouth, throat, or jaw soreness and hiccups. Nicotine can also raise heart rate and blood pressure. The nasal spray can cause nasal and throat irritation, sneezing, watery eyes, and a runny nose, and carries a higher potential for dependence than other NRT forms. Contact your provider or pharmacist if side effects bother you or do not go away.
How much does Nicotine cost without insurance?
The price of Nicotine without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Nicotine?
Common side effects of Nicotine may include: Fast, slow, pounding, or uneven heartbeat, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Dizziness, headache, upset stomach, drooling, vomiting, diarrhea, cold sweats, blurred vision, trouble hearing, confusion, fainting, or weakness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Nicotine?
Generic versions may be available for Nicotine. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Nicotine on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Nicotine?
The cheapest pharmacy for Nicotine depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Nicotine near you.

Nicotine Coupons & Prices

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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Nicotine replacement therapy (NRT) is an FDA-approved aid to quitting smoking that eases withdrawal symptoms and cravings, and it comes in over-the-counter forms (patch, gum, lozenge) as well as prescription forms like Nicotrol NS nasal spray. Because some NRT products can cost less with a coupon or when your provider writes a prescription, you can use an Rx.com nicotine coupon to compare today's price at pharmacies near you before you buy. Enter your ZIP above to see today's price on the form you want.

What nicotine replacement therapy is and how it works

Nicotine replacement therapy delivers a controlled, lower dose of nicotine without the tar and other harmful chemicals in cigarette smoke. By replacing some of the nicotine your body is used to, it reduces cravings and withdrawal symptoms while you break the habit of smoking. It is a nicotinic acetylcholine receptor agonist and is not a controlled substance.

NRT is sold under brand names including Nicorette, NicoDerm CQ, Nicotrol NS, Habitrol, and Commit, and in store-brand generics. Common forms include:

  • Transdermal patch (long-acting) - worn on the skin to provide a steady level of nicotine through the day.
  • Gum and lozenge (fast-acting, over the counter) - used as needed to handle sudden cravings.
  • Nasal spray (Nicotrol NS, prescription) - the fastest-acting form. The Nicotrol inhaler has been discontinued.

Many people do best with combination therapy - a long-acting patch plus a fast-acting gum, lozenge, or spray - which research shows works better than a single product. Any form works best when paired with a behavioral support or quit program.

How to save on nicotine with an Rx.com coupon

Even though most nicotine products are available over the counter, prices vary a lot from pharmacy to pharmacy, and some OTC items are cheaper with a coupon or when your provider writes a prescription. An Rx.com coupon lets you compare the cash price on the patch, gum, lozenge, or prescription nasal spray at pharmacies near you. Enter your ZIP above to see today's price, then show the coupon at the pharmacy counter.

A generic version of nicotine is widely available, and store-brand patches, gum, and lozenges are typically the lowest-cost option. There is no manufacturer copay savings card for nicotine NRT. If you use a specific brand such as Nicorette or NicoDerm CQ, you can check that manufacturer's official website for any current offers, though terms vary.

How nicotine compares to other quit-smoking options

Nicotine replacement is one of several proven ways to quit. The main prescription alternatives do not contain nicotine at all and work on the brain in different ways:

  • varenicline (brand Chantix) - a prescription pill that reduces cravings and blunts the reward from smoking.
  • bupropion (marketed for quitting as Zyban) - a prescription pill that can help reduce the urge to smoke.
  • Nicotrol - the prescription nicotine nasal spray form of NRT.

NRT has the advantage of being available over the counter and can be combined with a behavioral program. Some people use NRT together with a prescription medication under a clinician's guidance. Your provider can help you choose the approach most likely to work for you.

Safety and side effects

Nicotine NRT has no boxed warning, but use extra caution if you have had a recent heart attack (within about two weeks), serious or worsening irregular heartbeats, or severe or worsening chest pain (angina), because nicotine can raise your heart rate and blood pressure. Talk with your provider before using NRT if you are pregnant or breastfeeding.

Side effects depend on the form: skin irritation with the patch; mouth, throat, or jaw soreness and hiccups with gum or lozenges; and nasal or throat irritation, sneezing, watery eyes, and a runny nose with the nasal spray. The nasal spray carries a higher potential for dependence than other NRT forms. Nicotine is highly toxic if swallowed in overdose, so keep all products - including used patches and chewed gum - safely away from children and pets, since even small amounts can cause serious poisoning. This information is not medical advice; follow the package directions and ask your provider or pharmacist if you have questions.

Sources & accuracy

This Nicotine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Nicotine on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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