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Nicotine Polacrilex

Nicotine Polacrilex 100 Gum

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What is Nicotine Polacrilex?

Nicotine-polacrilex is an effective smoking cessation aid designed to help individuals quit smoking by reducing cravings. Available in various forms, this prescription medication works by delivering a controlled amount of nicotine to ease withdrawal symptoms. Users can find prescription online and explore cost-saving options through coupons and mail-order services.

Prescription savings · · · ·

What is Nicotine Polacrilex ?

Nicotine-polacrilex is an effective smoking cessation aid designed to help individuals quit smoking by reducing cravings. Available in various forms, this prescription medication works by delivering a controlled amount of nicotine to ease withdrawal symptoms. Users can find prescription online and explore cost-saving options through coupons and mail-order services.
  • Severe sore throat, open mouth sores or blisters
  • Fast, slow, pounding, or uneven heartbeat
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Dizziness, headache, upset stomach, drooling, vomiting, diarrhea, cold sweats, blurred vision, trouble hearing, confusion, fainting, or weakness
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Pregnant or breastfeeding women should only use this medicine as directed by a doctor. Smoking can seriously harm your unborn child. Try to stop smoking without using medicine. Although this medicine is believed to be safer than smoking, the risks of its use during pregnancy are not fully known.
  • Tell your doctor if you have diabetes, heart problems, high blood pressure, a stomach ulcer, or phenylketonuria (PKU).
  • This medicine may cause the following problems:High blood pressureIncrease in heart rate
  • If you are on a low-salt diet, talk to your doctor before you use this medicine.
Is nicotine polacrilex the same as Nicorette?
Nicotine polacrilex is the active ingredient, and Nicorette (and Nicorette Lozenge) is one brand that contains it. Many store-brand quit-smoking gums and lozenges, such as CVS Health, Up & Up, Amazon Basic Care, Leader, and Equate, contain the same nicotine polacrilex ingredient and work the same way. The generic versions are typically less expensive than the brand.
What is the difference between 2 mg and 4 mg nicotine lozenges?
The number is the nicotine dose per piece. Choose the 4 mg strength if you smoke your first cigarette within 30 minutes of waking up, and the 2 mg strength if your first cigarette is later than that. The stronger 4 mg dose is meant for people with heavier nicotine dependence. Follow the package directions and do not use more than the label allows.
How many nicotine lozenges or pieces of gum can you use per day?
Follow the maximum listed on your specific product's package, since limits differ by product and strength. As a general rule you use a piece when a craving hits and taper down over the program, but you should not exceed the daily maximum printed on the label. Using more than directed raises the risk of nicotine side effects like nausea, dizziness, and a rapid heartbeat.
How long should you use nicotine gum or lozenges to quit smoking?
Nicotine gum and lozenges are typically used on a step-down schedule over several weeks, gradually reducing how many pieces you use as cravings fade, per the directions on the package. Using them alongside a behavioral support or counseling program improves your chances of quitting for good. If you feel you still need them beyond the recommended period, talk with your doctor or pharmacist.
What are the side effects of nicotine polacrilex gum and lozenges?
Common side effects include mouth or throat irritation, hiccups, heartburn, nausea, sore mouth, and jaw ache from the gum. Stop use and ask a doctor if you notice mouth, teeth, or jaw problems, an irregular or rapid heartbeat or palpitations, or signs of too much nicotine such as nausea, vomiting, dizziness, weakness, or a racing heart. Ask a doctor before use if you have heart disease, an irregular heartbeat, uncontrolled high blood pressure, a stomach ulcer, or diabetes.
How much does Nicotine Polacrilex cost without insurance?
The price of Nicotine Polacrilex without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 45% off retail prices with a free Rx.com coupon.
What are the common side effects of Nicotine Polacrilex?
Common side effects of Nicotine Polacrilex may include: Severe sore throat, open mouth sores or blisters, Fast, slow, pounding, or uneven heartbeat, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Dizziness, headache, upset stomach, drooling, vomiting, diarrhea, cold sweats, blurred vision, trouble hearing, confusion, fainting, or weakness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Nicotine Polacrilex?
Generic versions may be available for Nicotine Polacrilex. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Nicotine Polacrilex on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Nicotine Polacrilex?
The cheapest pharmacy for Nicotine Polacrilex depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Nicotine Polacrilex near you.

Nicotine Polacrilex Coupons & Prices

Nicotine Polacrilex 100 Gum

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Nicotine Polacrilex Box — prescription drug image
Prescription
Nicotine Polacrilex 110 gum (1)
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Use the Rx.com nicotine polacrilex coupon above to check today's price on nicotine gum and lozenges at pharmacies near you. Nicotine polacrilex is the active ingredient in Nicorette and many store-brand quit-smoking products sold over the counter. Because some over-the-counter items ring up cheaper with a discount coupon (and sometimes when your prescriber writes for them), it is worth entering your ZIP above to compare before you buy.

What is nicotine polacrilex and how does it work?

Nicotine polacrilex is a nicotine replacement therapy (NRT) used as an over-the-counter aid to quitting smoking. It comes as a chewing gum and as a dissolving lozenge, in 2 mg and 4 mg strengths. When you chew the gum slowly or let the lozenge dissolve in your mouth, a controlled dose of nicotine is absorbed through the lining of your mouth (the buccal mucosa). That steady, lower dose helps ease the cravings and withdrawal symptoms that come with stopping cigarettes, without the smoke, tar, and other harmful chemicals in tobacco.

The strength you choose depends on how soon after waking you usually smoke: pick 4 mg if your first cigarette is within 30 minutes of waking, otherwise pick 2 mg. NRT works best as part of a behavioral support or counseling program rather than on its own. It is a nicotinic receptor agonist and carries no controlled-substance schedule.

How to use nicotine gum and lozenges correctly

These products are only absorbed properly when used the right way. For the lozenge, let it dissolve slowly over about 20 to 30 minutes; do not chew or swallow it. For the gum, use the "chew and park" method: chew slowly until you notice a peppery taste or tingle, then "park" the gum between your cheek and gum until the feeling fades, then chew again, repeating for about 30 minutes.

Both forms are meant to be used on a step-down schedule over several weeks as your cravings lessen. Follow the directions on the package for how many pieces per day and how to taper, and do not exceed the daily maximum listed. Eating or drinking (especially coffee, soda, or acidic drinks) right before or during use can reduce how much nicotine your body absorbs, so avoid it for about 15 minutes beforehand.

Cost and how to save with an Rx.com coupon

Nicotine polacrilex is widely available as a low-cost generic, sold under the Nicorette and Nicorette Lozenge brands and under many store labels including CVS Health, Up & Up (Target), Amazon Basic Care, Leader, and Equate. Prices vary by pharmacy, package size, and strength, so it pays to compare.

Even though it is an over-the-counter product, some shoppers pay less using a pharmacy discount coupon, and in some cases when a prescriber writes for it. Enter your ZIP above to see today's price and print or show your free Rx.com coupon at the pharmacy counter. There is no manufacturer copay card for this ingredient; the official Nicorette site lists current product options, and any promotional terms there vary.

Alternatives and related quit-smoking options

Nicotine polacrilex is one of several nicotine replacement options. In the US, the FDA-approved over-the-counter nicotine replacement forms are the gum, the lozenge, and the skin patch; the patch delivers a steady dose through the skin and can be combined with gum or lozenges under guidance. Nicotine nasal spray and the nicotine inhaler are also available, but only by prescription. If NRT alone is not enough, prescription non-nicotine medicines are an option to discuss with your provider.

  • Varenicline (formerly branded Chantix) is a prescription pill that reduces the urge to smoke and blunts the reward from nicotine.
  • Bupropion is a prescription medicine also used to help people quit smoking. The bupropion product FDA-approved for smoking cessation is sold under the brand Zyban; the same drug is sold as Wellbutrin for depression and is used off-label to help with quitting.

These prescription options work differently from nicotine gum and lozenges and are not sold over the counter. Your healthcare provider can help you choose the approach, or combination, most likely to work for you.

Safety, side effects, and who should ask a doctor first

Nicotine polacrilex is an over-the-counter product with no FDA boxed warning. Common side effects include mouth or throat irritation, hiccups, heartburn, nausea, sore mouth, and jaw ache with the gum. Stop use and ask a doctor if you develop mouth, teeth, or jaw problems, an irregular or rapid heartbeat or palpitations, or signs of taking too much nicotine such as nausea, vomiting, dizziness, weakness, or a racing heart.

Ask a doctor before use if you have heart disease, had a recent heart attack, have an irregular heartbeat, uncontrolled high blood pressure, a stomach ulcer, or diabetes, or if you take prescription medicine for depression or asthma. If you are pregnant or breastfeeding, talk with a healthcare provider first, since smoking and nicotine can both harm the baby. Keep these products out of reach of children and pets, because nicotine can be toxic or even fatal if a child chews or swallows it. This is general information, not medical advice; check with your provider or pharmacist about your situation.

Sources & accuracy

This Nicotine Polacrilex information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Nicotine Polacrilex on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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