Pioglitazone Hcl
Pioglitazone HCl 30MG
What is Pioglitazone Hcl?
Actos is used to treat type 2 diabetes. The generic version of Actos is Pioglitazone. On average Actos is priced at about $700 for a supply of 30, 30 mg tablets. Luckily, you can use our Rx.com savings offer to receive an Actos discount of up to 80% off the retail price at participating pharmacies near you.Side Effects
- Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Blurred vision or changes in vision
Warnings
- Tell your doctor if you are pregnant or breastfeeding. If you had problems ovulating or have irregular periods, this medicine may cause you to ovulate, which could lead to pregnancy if you are sexually active. Talk to your doctor about effective birth control while you are using this medicine.
- Tell your doctor if you have kidney disease, liver disease, heart disease, heart failure, macular edema (swelling of the back of the eye), or a history of bladder cancer.
- This medicine may cause the following problems:Congestive heart failureLow blood sugar levelsLiver problemsIncreased risk of broken bones, especially in womenIncreased risk of bladder cancer, if you use this medicine for a long time
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Prescription savings · · · ·
What is Pioglitazone Hcl ?
Actos is used to treat type 2 diabetes. The generic version of Actos is Pioglitazone. On average Actos is priced at about $700 for a supply of 30, 30 mg tablets. Luckily, you can use our Rx.com savings offer to receive an Actos discount of up to 80% off the retail price at participating pharmacies near you.- Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Blurred vision or changes in vision
- Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing
- Severe joint pain
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Change in how often or how much you urinate, painful urination, lower back or side pain, blood in your urine
- Tell your doctor if you are pregnant or breastfeeding. If you had problems ovulating or have irregular periods, this medicine may cause you to ovulate, which could lead to pregnancy if you are sexually active. Talk to your doctor about effective birth control while you are using this medicine.
- Tell your doctor if you have kidney disease, liver disease, heart disease, heart failure, macular edema (swelling of the back of the eye), or a history of bladder cancer.
- This medicine may cause the following problems:Congestive heart failureLow blood sugar levelsLiver problemsIncreased risk of broken bones, especially in womenIncreased risk of bladder cancer, if you use this medicine for a long time
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing
- Unusual tiredness or weakness
Pioglitazone Hcl Coupons & Prices
Pioglitazone HCl 30MG
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Looking for a pioglitazone HCl coupon? Pioglitazone hydrochloride is the low-cost generic version of Actos, a once-daily oral pill that helps improve blood sugar control in adults with type 2 diabetes. Because it is already available as a generic, the cash price is usually modest, but what you actually pay can vary widely from one pharmacy to the next. Rx.com compares live prices across more than 60,000 pharmacies so you can find the lowest one near you. Enter your ZIP above to see today's price and print or text yourself a free discount coupon.
What is pioglitazone and how does it work?
Pioglitazone belongs to a class of diabetes medicines called thiazolidinediones (TZDs), sometimes described as insulin sensitizers. It works by helping your body respond better to its own insulin, which lowers blood sugar over time. It is used as an addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Pioglitazone may be taken on its own or combined with other diabetes medicines such as metformin, a sulfonylurea like glimepiride, or insulin. It is not used for type 1 diabetes or for diabetic ketoacidosis. Your doctor decides whether it fits your treatment plan.
How much does generic pioglitazone cost without insurance?
Because pioglitazone is available as a generic, it is generally one of the more affordable diabetes medicines when you pay cash. Even so, pharmacies set their own cash prices, and the difference between the highest and lowest price in the same town can be surprisingly large. That is exactly why comparing matters.
Rx.com checks live prices at more than 60,000 pharmacies and gives you a free discount coupon you can use whether or not you have insurance. Enter your ZIP above to see today's price near you. If your prescription is written for the brand, you can also compare the price of Actos on its own page.
Alternatives and related diabetes medicines
Pioglitazone is one of several oral options for type 2 diabetes, and it is often used alongside other medicines. Related drugs you can compare on Rx.com include:
- Actos - the brand-name version of pioglitazone.
- Metformin - a common first-line diabetes medicine, frequently paired with pioglitazone.
- Actoplus Met - a combination product containing pioglitazone plus metformin in one pill.
- Rosiglitazone - another thiazolidinedione in the same drug class.
- Glimepiride - a sulfonylurea that may be combined with pioglitazone.
Which medicine is right for you depends on your health history and other conditions. Your provider can help you weigh the options.
Important safety information
Pioglitazone carries a boxed warning: it can cause or worsen congestive heart failure because it may lead to fluid retention. It should not be used in people with more advanced (NYHA Class III/IV) heart failure and is not recommended for those with symptomatic heart failure. Tell your doctor right away about rapid weight gain, swelling (edema), or shortness of breath.
Other important risks to be aware of include a possible increased risk of bladder cancer with use longer than one year, an increased risk of bone fractures (especially in women), liver problems, swelling at the back of the eye (macular edema), and low blood sugar when combined with insulin or a sulfonylurea. Premenopausal women who do not ovulate regularly may resume ovulation. This information is not medical advice; talk with your doctor or pharmacist about whether pioglitazone is right for you and report any side effects.
This Pioglitazone Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Pioglitazone Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.