Prednisolone
Prednisolone
What is Prednisolone?
Prednisolone is a prescription corticosteroid used to treat a wide range of inflammatory and autoimmune conditions, including allergies, asthma, arthritis, skin disorders, and certain eye diseases. It works by reducing inflammation and suppressing an overactive immune response to help relieve pain, swelling, and other symptoms.
Side Effects
- Trouble seeing, eye pain, headache
- Muscle pain or weakness
- Skin changes or growths
Warnings
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding or if you have kidney problems, liver disease, heart failure, high blood pressure, a recent heart attack, diabetes, glaucoma, osteoporosis, or thyroid problems. Tell your doctor about any infection you have. Also tell your doctor if you have had mental or emotional problems (such as depression) or stomach or bowel problems (such as an ulcer or diverticulitis).
- This medicine may cause the following problems:Mood or behavior changesHigher blood pressure, retaining water, changes in salt or potassium levels in your bodyCataracts or glaucoma (with long-term use)Weak bones or osteoporosis (with long-term use)Slow growth in children (with long-term use)Muscle problems (with high doses, especially if you have myasthenia gravis or similar nerve and muscle problems)
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- This medicine could cause you to get infections more easily. Tell your doctor right away if you are exposed to chicken pox, measles, or other serious infection. Tell your doctor if you had a serious infection in the past, such as tuberculosis or herpes.
Prescription savings · · · ·
What is Prednisolone ?
Prednisolone is a prescription corticosteroid used to treat a wide range of inflammatory and autoimmune conditions, including allergies, asthma, arthritis, skin disorders, and certain eye diseases. It works by reducing inflammation and suppressing an overactive immune response to help relieve pain, swelling, and other symptoms.
- Trouble seeing, eye pain, headache
- Muscle pain or weakness
- Skin changes or growths
- Severe stomach pain, nausea, vomiting, or red or black stools
- Fever, chills, cough, sore throat, and body aches
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Dark freckles, skin color changes, coldness, weakness, tiredness, nausea, vomiting, weight loss
- Depression, trouble sleeping, unusual thoughts, feelings, or behaviors
- Dry mouth, increased thirst, muscle cramps, nausea or vomiting, uneven heartbeat
- Rapid weight gain, swelling in your hands, ankles, or feet
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding or if you have kidney problems, liver disease, heart failure, high blood pressure, a recent heart attack, diabetes, glaucoma, osteoporosis, or thyroid problems. Tell your doctor about any infection you have. Also tell your doctor if you have had mental or emotional problems (such as depression) or stomach or bowel problems (such as an ulcer or diverticulitis).
- This medicine may cause the following problems:Mood or behavior changesHigher blood pressure, retaining water, changes in salt or potassium levels in your bodyCataracts or glaucoma (with long-term use)Weak bones or osteoporosis (with long-term use)Slow growth in children (with long-term use)Muscle problems (with high doses, especially if you have myasthenia gravis or similar nerve and muscle problems)
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- This medicine could cause you to get infections more easily. Tell your doctor right away if you are exposed to chicken pox, measles, or other serious infection. Tell your doctor if you had a serious infection in the past, such as tuberculosis or herpes.
- Tell your doctor about any extra stress or anxiety in your life. Your dose might need to be changed for a short time.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Every other day schedule: You might have some mild symptoms of your illness on the day you do not take the medicine (the €œoff€ day). If this is a problem for you, tell your doctor.
Prednisolone Coupons & Prices
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Prednisolone prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 60ml of 15mg/5ml · Bottle | 60 | — | $35.69 |
| 240ml of 15mg/5ml oral soln · Bottle | 60 | $46.49 | $35.69 |
| 240ml of 15mg/5ml · Bottle | 60 | $83.59 | $35.69 |
| 480ml of 15mg/5ml oral soln · Bottle | 24 | $43.29 | $17.28 |
| 480ml of 15mg/5ml · Bottle | 24 | $37.21 | $17.28 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Looking for a prednisolone coupon? Prednisolone is a widely used generic corticosteroid, so it is already one of the more affordable prescriptions, but the cash price can still vary a lot from one pharmacy to the next. Rx.com compares prices across more than 60,000 pharmacies so you can find a lower price near you and use a free discount coupon at the counter. Enter your ZIP above to see today's price on prednisolone tablets, oral liquid, and orally disintegrating tablets (ODT) in your area.
What is prednisolone and how does it work?
Prednisolone is a systemic corticosteroid (a glucocorticoid, or "steroid"). It works by calming inflammation and dialing down an overactive immune system. Because of this broad action, it is FDA-approved for a wide range of conditions, including hormone (endocrine) disorders such as adrenal insufficiency, rheumatic conditions like rheumatoid arthritis and lupus, severe allergic reactions, asthma and other respiratory diseases, certain skin and blood disorders, some cancers such as leukemia and lymphoma, inflammatory bowel disease, certain eye and neurologic conditions (including multiple sclerosis flares), nephrotic syndrome, and preventing or treating organ transplant rejection.
It is also commonly used in children as a short oral course, often as a liquid or orally disintegrating tablet, for asthma flare-ups and croup. Prednisolone comes in several forms and brand names, including Millipred, Orapred ODT, Prelone, Pediapred, Veripred 20, Bubbli-Pred, Flo-Pred, and Cotolone. Your provider decides the dose and length of treatment based on your condition.
How much does prednisolone cost without insurance?
Prednisolone is available as an FDA-approved generic, so it is generally low-cost compared with brand-name medications. That said, cash prices are not the same everywhere. Two pharmacies on the same street can charge very different amounts for the exact same prescription, which is why comparing before you fill matters. The form you are prescribed (standard tablets, oral solution, or the orally disintegrating tablet) also affects the price.
With a free Rx.com discount coupon, you can compare the cash price across more than 60,000 pharmacies and bring the lowest one to the counter, no insurance required. There is no manufacturer copay savings card for prednisolone. Enter your ZIP above to see today's price near you.
Prednisolone vs. related corticosteroids
Prednisolone is one of several closely related oral steroids, and providers choose among them based on the condition, the patient, and how the body processes the drug. The most common comparison is with prednisone: prednisone is inactive until the liver converts it into prednisolone, so prednisolone is sometimes preferred when liver conversion is a concern, such as in young children or people with liver problems.
Other related glucocorticoids include methylprednisolone, dexamethasone, and hydrocortisone. They differ in potency and how long they act. These are not interchangeable on your own, so only switch on your provider's advice. If you are prescribed a specific product, you can compare its cash price on Rx.com the same way.
Prednisolone safety and side effects
Prednisolone has no boxed warning, but it does carry real risks, especially with higher doses or longer use. Because it suppresses the immune system, it can raise your risk of infection and can hide the usual signs of one. Avoid exposure to chickenpox and measles while taking it, and talk to your provider before receiving any live vaccines. It should not be used if you have a systemic fungal infection. This is general information, not medical advice, so follow your provider's instructions for your situation.
Do not stop prednisolone suddenly after taking it for a prolonged period. Stopping abruptly can trigger adrenal insufficiency or an adrenal crisis, so the dose usually needs to be lowered gradually (tapered). Longer-term use can lead to bone thinning (osteoporosis), higher blood sugar or worsened diabetes, high blood pressure, fluid retention, mood or psychiatric changes, cataracts or glaucoma, slowed growth in children, Cushingoid changes, and a higher risk of stomach ulcers or bleeding. The guiding principle is the lowest effective dose for the shortest time needed. Call your provider with any concerning symptoms.
This Prednisolone information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Prednisolone on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
Prednisolone — Articles & Guides
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.