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Prednisolone Acetate Bottle — prescription drug image

Prednisolone Acetate

Prednisolone Acetate

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What is Prednisolone Acetate?

Prednisolone Acetate is a generic medication used to treat swelling of the eyes. The average price of Prednisolone Acetate is around $118 for a supply of 25 ml of 20 mg ophthalmic solution. Use our Rx.com savings offer to get great discounts on Prednisolone Acetate at participating pharmacies near you.

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What is Prednisolone Acetate ?

Prednisolone Acetate is a generic medication used to treat swelling of the eyes. The average price of Prednisolone Acetate is around $118 for a supply of 25 ml of 20 mg ophthalmic solution. Use our Rx.com savings offer to get great discounts on Prednisolone Acetate at participating pharmacies near you.

  • Blurred vision, changes in vision
  • Changes in skin color, dark freckles
  • Increased pain, redness, discharge, swelling, or irritation of the eye
  • Cold feeling, weakness, tiredness, nausea, vomiting, weight loss
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Weight gain around your neck, upper back, breast, face, or waist
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it. Tell your doctor if you had a cataract surgery.
  • This medicine may cause the following problems:Eye problems (including glaucoma, cataracts, infections) with long-term useIncreased pressure in your eyeSlow healing of the eye
  • Tell your doctor if you are pregnant or breastfeeding, or if you have glaucoma or a history of herpes infection.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
What is prednisolone acetate eye drops used for?

Prednisolone acetate is a steroid eye drop used to treat steroid-responsive inflammation of the front of the eye, including the conjunctiva, cornea, and anterior segment. It is approved for conditions such as allergic conjunctivitis, acne rosacea affecting the eye, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, certain infective conjunctivitides, and inflammation from corneal burns or a foreign body. It is also very commonly prescribed for inflammation after eye surgery, such as cataract surgery, and for uveitis flares.

How long can you use prednisolone acetate eye drops?

You should use prednisolone acetate only for as long as your eye doctor directs. Steroid eye drops are usually meant for short-term use because prolonged use can raise pressure inside the eye, contribute to cataracts, and slow healing. If you use it for more than about 10 days, your doctor may monitor your eye pressure. Do not stop early or extend treatment on your own; follow your prescriber's instructions.

Is prednisolone acetate a steroid?

Yes. Prednisolone acetate is a corticosteroid, also called a glucocorticoid. In eye drop form it works as an anti-inflammatory to reduce swelling, redness, and irritation in the eye.

What are the side effects of prednisolone acetate ophthalmic?

Possible side effects, especially with prolonged use, include increased pressure inside the eye (which can lead to glaucoma and optic nerve damage), posterior subcapsular cataracts, and delayed wound healing. Steroids can also mask or worsen eye infections and make secondary bacterial, viral, or fungal infections more likely, and long-term use has been linked to thinning of the cornea or sclera. The suspension contains sodium bisulfite, which can cause allergic-type reactions in sensitive people. Contact your eye doctor if you notice eye pain, worsening vision, or new symptoms.

Do you have to shake prednisolone acetate eye drops before using them?

Yes. Prednisolone acetate is a suspension, meaning the medicine settles to the bottom over time. Shake the bottle well before every use so you get an even, correct dose. Follow the directions on your prescription label and ask your pharmacist if you are unsure.

How much does prednisoLONE Acetate 5ML of 1% cost without insurance?
The price of prednisoLONE Acetate 5ML of 1% without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of prednisoLONE Acetate 5ML of 1%?
Common side effects of prednisoLONE Acetate 5ML of 1% may include: Blurred vision, changes in vision, Changes in skin color, dark freckles, Increased pain, redness, discharge, swelling, or irritation of the eye, Cold feeling, weakness, tiredness, nausea, vomiting, weight loss, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of prednisoLONE Acetate 5ML of 1%?
Generic versions may be available for prednisoLONE Acetate 5ML of 1%. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search prednisoLONE Acetate 5ML of 1% on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for prednisoLONE Acetate 5ML of 1%?
The cheapest pharmacy for prednisoLONE Acetate 5ML of 1% depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for prednisoLONE Acetate 5ML of 1% near you.

Prednisolone Acetate Coupons & Prices

Prednisolone Acetate

Prescriptions & Refills
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Prednisolone Acetate Bottle — prescription drug image
Prescription
Prednisolone Acetate 5ml of 1% ophth susp (eye) (1)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Looking for a prednisolone acetate coupon? Prednisolone acetate ophthalmic is the low-cost generic version of brand-name steroid eye drops like Pred Forte, Pred Mild, Omnipred, and Econopred Plus. Because it is already available as a generic, cash prices are often modest, but they still vary widely from one pharmacy to the next, so comparing before you fill can make a real difference. Enter your ZIP above to see today's price at pharmacies near you. Rx.com compares prices across more than 60,000 pharmacies so you can find the best cash price without insurance.

What is prednisolone acetate and how does it work?

Prednisolone acetate is a corticosteroid (glucocorticoid) eye drop used to treat steroid-responsive inflammation of the eye. As an anti-inflammatory suspension, it calms swelling, redness, and irritation affecting the conjunctiva, cornea, and the front (anterior) portion of the eye. It is FDA-approved for conditions such as allergic conjunctivitis, acne rosacea affecting the eye, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitides, and inflammation caused by corneal injury from chemical, radiation, or thermal burns or a foreign body. Doctors also very commonly prescribe it for inflammation after eye surgery, such as cataract surgery, and for uveitis flares.

It comes as a suspension in two strengths: 1% (sold as Pred Forte and Omnipred) and 0.12% (sold as Pred Mild). Because it is a suspension rather than a solution, the medicine settles over time and must be shaken well before every use so you get an even dose. This is a summary and not medical advice; your eye doctor will choose the strength and schedule that fits your condition.

Prednisolone acetate cost and savings without insurance

Prednisolone acetate is available as a generic, which generally keeps the cash price lower than the brand-name versions like Pred Forte. Even so, what you pay out of pocket can differ significantly depending on which pharmacy you use, the bottle size, and the strength (1% versus 0.12%). That price spread is exactly why comparing pharmacies matters, even for an inexpensive generic.

Rx.com compares prednisolone acetate prices across more than 60,000 U.S. pharmacies so you can find the lowest cash price near you, with or without insurance. Prices change often and are shown live, so enter your ZIP code above to see today's price and the free coupon you can bring to the pharmacy counter.

Prednisolone acetate vs. other steroid eye drops

Prednisolone acetate is one of several corticosteroid eye drops your doctor might consider. Related options include prednisolone in its other ophthalmic forms, along with dexamethasone, loteprednol, fluorometholone, and difluprednate. These drops differ in potency, how likely they are to raise eye pressure, and the conditions they are typically used for.

If your prescription is written for a brand, you can also compare it to the generic. The brand Pred Forte and generic prednisolone acetate 1% contain the same active ingredient. Ask your prescriber or pharmacist whether a generic or an alternative steroid is appropriate for you, then compare cash prices here to find the best value.

Safety and important warnings

Prednisolone acetate has no boxed warning, but steroids used in the eye carry real risks, especially with prolonged use. Long-term use can raise pressure inside the eye (which can lead to glaucoma and optic nerve damage), cause posterior subcapsular cataracts, and slow wound healing. Because steroids can mask or worsen an eye infection, they may allow secondary bacterial, viral, or fungal infections to develop, and prolonged use has been linked to thinning of the cornea or sclera and, rarely, perforation. For these reasons, your doctor may check your eye pressure if you use it beyond about 10 days.

This medicine should not be used in most viral corneal or conjunctival diseases, including epithelial (dendritic) herpes simplex keratitis, vaccinia, and varicella, or in mycobacterial or fungal eye infections. The suspension contains sodium bisulfite, which can cause allergic-type or, rarely, anaphylactic reactions in sensitive people. Shake well before use, and never inject it. This is general information, not medical advice; use it exactly as prescribed and contact your eye doctor if you have pain, worsening vision, or new symptoms.

Sources & accuracy

This Prednisolone Acetate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Prednisolone Acetate on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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