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Prednisolone-Bromfenac Bottle — prescription drug image

Prednisolone-Bromfenac

prednisoLONE-Bromfenac 5ML of 1-0.075%

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What is Prednisolone-Bromfenac?

Prednisolone-Bromfenac is a combination ophthalmic medication that unites an anti-inflammatory steroid, prednisolone, with a nonsteroidal anti-inflammatory drug (NSAID), bromfenac. This dual-action formula is designed to reduce inflammation, alleviate pain, and provide symptomatic relief in conditions affecting the eyes such as post-operative swelling and pain.

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What is Prednisolone-Bromfenac ?

Prednisolone-Bromfenac is a combination ophthalmic medication that unites an anti-inflammatory steroid, prednisolone, with a nonsteroidal anti-inflammatory drug (NSAID), bromfenac. This dual-action formula is designed to reduce inflammation, alleviate pain, and provide symptomatic relief in conditions affecting the eyes such as post-operative swelling and pain.

  • Increased susceptibility to infections (prednisolone)
  • Mood swings, including irritability, depression, and euphoria (prednisolone)
  • Stomach pain, ulcers or bleeding (bromfenac)
  • Blurred vision or other visual disturbances (bromfenac)
  • Avoid use in patients with known allergy to NSAIDs or corticosteroids
  • Use with caution in patients with existing peptic ulcer disease or gastrointestinal bleeding
  • Long term use of steroids may lead to osteoporosis, adrenal suppression and delayed wound healing
  • Potential increased health risks with chronic use such as cardiovascular events or gastrointestinal bleeding (bromfenac)
What is prednisolone-bromfenac used for?

Prednisolone-bromfenac is a combined eye drop used after cataract or other eye surgery to control inflammation, pain, redness, and swelling. The prednisolone (a steroid) reduces inflammation broadly, and the bromfenac (an NSAID) blocks prostaglandins that cause pain and inflammation and helps lower the risk of cystoid macular edema. Combining both into one drop simplifies the after-surgery drop schedule.

Is prednisolone-bromfenac an FDA-approved eye drop?

No. There is no FDA-approved brand of the fixed prednisolone-plus-bromfenac combination. It is prepared by licensed compounding pharmacies for an individual prescription, so the FDA has not reviewed this specific combination for safety or effectiveness. The individual ingredients, prednisolone acetate and bromfenac, are each FDA-approved on their own.

How do you use prednisolone-bromfenac drops after cataract surgery?

Use the drops exactly as your eye surgeon directs, since compounded regimens are individualized. Generally you place the prescribed number of drops in the operated eye on the schedule your surgeon sets and continue for the full course, even if the eye feels better. Wash your hands first, avoid touching the dropper tip to your eye, and keep your monitoring appointments so your doctor can check your eye pressure and cornea. Always follow your own prescription instructions rather than general guidance.

What are the side effects of combined prednisolone and bromfenac eye drops?

Common effects include brief stinging or burning when the drop goes in. More serious concerns come from each ingredient: the NSAID (bromfenac) can slow corneal healing and, especially with a steroid or in at-risk eyes, has been associated with corneal thinning, erosion, ulceration, or rarely perforation. The steroid (prednisolone) can raise eye pressure, promote glaucoma or cataract, delay healing, and mask or worsen eye infections. Rare allergic reactions can occur. Report any new eye pain, vision changes, or surface breakdown to your ophthalmologist right away.

Can I use prednisolone and bromfenac eye drops together at the same time?

Yes, they are often used together after eye surgery, which is why they are sometimes compounded into a single combination drop. However, combining a steroid and an NSAID can increase the risk of corneal healing problems in some eyes, so this should only be done under an ophthalmologist's direction with monitoring of your eye pressure and cornea. If you use them as separate bottles, follow your surgeon's instructions on timing and spacing between drops.

How much does prednisoLONE-Bromfenac 5ML of 1-0.075% cost without insurance?
The price of prednisoLONE-Bromfenac 5ML of 1-0.075% without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of prednisoLONE-Bromfenac 5ML of 1-0.075%?
Common side effects of prednisoLONE-Bromfenac 5ML of 1-0.075% may include: Increased susceptibility to infections (prednisolone), Mood swings, including irritability, depression, and euphoria (prednisolone), Stomach pain, ulcers or bleeding (bromfenac), Blurred vision or other visual disturbances (bromfenac). This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of prednisoLONE-Bromfenac 5ML of 1-0.075%?
Generic versions may be available for prednisoLONE-Bromfenac 5ML of 1-0.075%. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search prednisoLONE-Bromfenac 5ML of 1-0.075% on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for prednisoLONE-Bromfenac 5ML of 1-0.075%?
The cheapest pharmacy for prednisoLONE-Bromfenac 5ML of 1-0.075% depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for prednisoLONE-Bromfenac 5ML of 1-0.075% near you.

Prednisolone-Bromfenac Coupons & Prices

prednisoLONE-Bromfenac 5ML of 1-0.075%

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Prednisolone-Bromfenac Bottle — prescription drug image
Prescription
Prednisolone-Bromfenac 5ml of 1-0.075% ophth soln (eye) (0.2)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Prednisolone-Bromfenac prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
5ml of 1-0.075% · Bottle 5 $58.59 $44.12
5ml of 1-0.075% ophth soln (eye) · Bottle 5 $58.79
5ml of 1-0.075% ophth susp (eye) · Bottle 5 $43.14

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a prednisolone-bromfenac coupon? Rx.com compares cash prices on this compounded ophthalmic eye-drop combination across more than 60,000 pharmacies so you can find today's lowest price near you. Prednisolone-bromfenac blends a corticosteroid (prednisolone acetate) with an NSAID (bromfenac) into a single drop that eye surgeons commonly prescribe after cataract surgery to control inflammation, pain, and swelling. Because it is a compounded medication, the cash price can vary widely from one pharmacy to the next, so comparing before you fill matters. Enter your ZIP above to see today's price and print or text yourself a free discount coupon.

What is prednisolone-bromfenac and how does it work?

Prednisolone-bromfenac is a combination eye drop that pairs two anti-inflammatory medicines in one bottle: prednisolone acetate, a corticosteroid, and bromfenac, a nonsteroidal anti-inflammatory drug (NSAID). The prednisolone component broadly suppresses inflammation, while the bromfenac component blocks prostaglandins, the chemicals that drive inflammation and pain and that can contribute to cystoid macular edema (swelling at the back of the eye). Used together after cataract or other eye surgery, they help control postoperative inflammation, pain, redness, and swelling.

The main appeal is convenience: combining both medicines into a single drop simplifies what would otherwise be a multi-bottle, multi-drop regimen after surgery, which can make it easier to stick to the schedule your surgeon sets. Some compounded versions add an antibiotic as well and are sold under names like Pred-Gati-Brom or Pred-Moxi-Brom. Important: this fixed prednisolone-plus-bromfenac combination is not an FDA-approved product. It is prepared by licensed compounding pharmacies for an individual prescription, so the FDA has not reviewed this specific combination for safety or effectiveness.

Prednisolone-bromfenac cost and how to save without insurance

Because prednisolone-bromfenac is compounded rather than a mass-produced brand, there is no manufacturer savings card for the combination, and cash prices can differ substantially between pharmacies, especially between local compounding pharmacies. That variation is exactly why comparing prices pays off. Both individual ingredients are available as low-cost generics, but the compounded combined drop is priced by each pharmacy, so it helps to check more than one.

Rx.com compares cash prices across 60,000+ U.S. pharmacies and gives you a free discount coupon you can use whether or not you have insurance. There are no membership fees. To see what you would pay, enter your ZIP code above; the price shown is live and updates by location and pharmacy. If your surgeon wrote for the individual components instead, you can also compare prednisolone and bromfenac separately.

Alternatives and related eye drops

Whether a combined drop or separate bottles are right for you is a decision for your eye surgeon, but it helps to know the related options so you can compare prices. The individual ingredients are widely stocked generics: the steroid prednisolone acetate (brands Pred Forte, Omnipred) and the NSAID bromfenac (brands Prolensa, BromSite, Bromday). Another commonly used ophthalmic NSAID is ketorolac.

Some surgeons prefer an all-in-one compounded drop that also includes an antibiotic to further simplify the post-surgery routine, such as prednisolone-moxifloxacin-bromfenac or prednisolone-gatifloxacin-bromfenac. You can look up any of these on Rx.com to compare today's cash price near you.

Safety, side effects, and what to watch for

This is general information, not medical advice; always follow your ophthalmologist's instructions and ask them about your specific situation. Prednisolone-bromfenac has no boxed warning, but both ingredients carry cautions. As an ophthalmic NSAID, bromfenac can slow corneal wound healing and, particularly when combined with a topical steroid or used in at-risk eyes (dry eye, diabetes, rheumatoid arthritis, or repeat surgery), has been linked to corneal thinning, erosion, ulceration, and in rare cases perforation. Tell your doctor promptly if your eye develops a breakdown of the surface. The steroid (prednisolone) can raise pressure inside the eye (potentially causing glaucoma and optic-nerve damage), promote cataract formation, delay healing, and mask or worsen eye infections, including bacterial, fungal, and viral infections such as herpes.

Both drops may sting or burn briefly when instilled. Rare hypersensitivity or allergic reactions have been reported with bromfenac, and people with sulfite sensitivity should mention it. These drops are for use in the eye only and require your ophthalmologist to monitor eye pressure and the cornea during treatment. And because this is a compounded medication, its potency and sterility are not FDA-verified, so it should come from a reputable licensed compounding pharmacy. Do not stop or change your drops without talking to your surgeon.

Sources & accuracy

This Prednisolone-Bromfenac information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Prednisolone-Bromfenac on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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