Silver Sulfadiazine Coupons & Prices

Looking for a silver sulfadiazine coupon? Silver sulfadiazine is a low-cost generic prescription cream (brand names include Silvadene, SSD, SSD AF, and Thermazene) used to prevent and treat infection in second- and third-degree burns. Because it is already a generic, cash prices are usually modest, but what you pay can still vary widely from one pharmacy to the next. Enter your ZIP code above to compare today's price across more than 60,000 U.S. pharmacies and get a free Rx.com discount that works whether or not you have insurance.

What is silver sulfadiazine and how does it work?

Silver sulfadiazine is a topical sulfonamide antibiotic (an antibacterial and antimicrobial). It is FDA-approved to prevent and treat wound infection, including sepsis, in people with second- and third-degree burns. Applied directly to the burned skin, it stops the growth of bacteria and yeast on the surface of the wound, which helps lower the risk of infection while the burn heals.

It is sold as a cream under the brand names Silvadene, SSD, SSD AF, and Thermazene, and a substitutable generic is available. This medicine is for external use on the skin only.

Silver sulfadiazine cost and savings without insurance

Silver sulfadiazine is a generic, so it is generally one of the more affordable topical antibiotics, and there is no brand-name manufacturer savings card for it. Even so, the cash price is not the same everywhere; pharmacies set their own prices, so the same tube can cost noticeably more at one store than another nearby. That is why comparing before you fill is worth the minute it takes.

Enter your ZIP code above to see today's price at pharmacies near you and print or text yourself a free Rx.com discount card. Rx.com compares prices across more than 60,000 pharmacies, and the discount can be used with or without insurance, whichever gives you the lower price at the counter.

Related and alternative topical antibiotics

Silver sulfadiazine is used specifically for burns. For other minor skin infections, cuts, or wounds, a provider may choose a different topical antibiotic. Depending on the situation, related options include:

• Mupirocin — a topical antibiotic often used for impetigo and certain skin infections
• Bacitracin — a topical antibiotic used to help prevent infection in minor scrapes and cuts
• Neomycin — a topical antibiotic, often combined with others in first-aid ointments
• Sulfamethoxazole-trimethoprim — an oral sulfa-containing antibiotic for certain systemic infections

These are not interchangeable, and each fits a different situation. Your provider chooses the right one based on your wound and history. This is general information, not medical advice.

Safety, side effects, and who should not use it

Common local effects include burning, itching, rash, pain, and skin discoloration. Silver sulfadiazine should not be used in premature infants or newborns under 2 months of age (risk of kernicterus) or in late pregnancy. Because it is a "sulfa" drug, people with a sulfonamide allergy may have cross-sensitivity and can experience serious hypersensitivity or skin reactions. It can also cause hemolysis in people with G6PD deficiency.

Rare but serious effects include transient low white blood cell counts (leukopenia/neutropenia), methemoglobinemia, and, when applied to large burn areas, hyperosmolality; prolonged use can cause silver or gray staining of the skin. Because the medicine can be absorbed into the body when spread over large burns, use it exactly as prescribed, keep it away from the eyes, and talk to your provider or pharmacist about any allergies or health conditions before starting.