Levonorgest-Eth Estrad 91-Day Coupons & Prices

Looking for a Simpesse coupon? Simpesse is an FDA-approved generic version of the extended-cycle birth control brand Seasonique, so it is already a lower-cost option than the brand. Even so, the cash price for the same 91-day pack can vary widely from one pharmacy to another, which is why comparing before you fill matters. Rx.com checks prices across more than 60,000 U.S. pharmacies and gives you a free discount coupon you can use at the counter. Enter your ZIP above to see today's Simpesse price near you.

What is Simpesse and how does it work?

Simpesse is a combination hormonal contraceptive that pairs an estrogen (ethinyl estradiol) with a progestin (levonorgestrel). It is the generic equivalent of the reference brand Seasonique and is FDA-approved to prevent pregnancy in women who choose an oral contraceptive. Like other combination pills, it works mainly by preventing ovulation, along with changes to cervical mucus and the uterine lining that make pregnancy less likely.

Simpesse uses an extended-cycle, 91-day regimen: 84 white tablets containing levonorgestrel 0.15 mg with ethinyl estradiol 0.03 mg, followed by 7 light-blue tablets of low-dose ethinyl estradiol 0.01 mg. This schedule is designed to produce a scheduled menstrual period roughly once every three months instead of monthly. Simpesse is not indicated for use in postmenopausal women.

Simpesse cost and coupon savings

Because Simpesse is a generic, it is generally far less expensive than the brand it copies. The catch is that pharmacies set their own cash prices, so the amount you pay for the same extended-cycle pack can differ a lot depending on where you fill it. That price spread is exactly why it pays to compare rather than assume every pharmacy charges the same.

Rx.com compares Simpesse prices across more than 60,000 pharmacies and provides a free discount coupon that works whether or not you have insurance. If you are paying cash, the coupon price may be lower than a standard retail price, and it can also come in handy when a plan does not cover this particular formulation. Enter your ZIP above to see today's price and print or text yourself the coupon.

Simpesse alternatives and related options

Simpesse is one of several interchangeable versions of the same levonorgestrel/ethinyl estradiol extended-cycle formulation. If your prescriber writes for the brand or a different generic, comparing prices across equivalents can help you find the best cash price:

• Seasonique — the reference brand Simpesse is based on
• Levonorgestrel-ethinyl estradiol — the underlying generic combination
• Camrese and Amethia — other equivalents of this extended-cycle regimen
• Jolessa — a related levonorgestrel/ethinyl estradiol extended-cycle option

These products are pharmacist-substitutable equivalents in most cases, but which one you receive can depend on your pharmacy's stock and your prescription. Ask your prescriber or pharmacist whether switching among them is appropriate for you, then use Rx.com to compare the price of whichever one you are prescribed.

Important safety information

Simpesse carries a boxed warning: cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives, and this risk rises with age and heavy smoking (15 or more cigarettes a day). Women over 35 who smoke should not use combination hormonal contraceptives. Other serious risks include blood clots in the veins and arteries (such as DVT, pulmonary embolism, stroke, and heart attack), high blood pressure, liver tumors, gallbladder disease, and worsening migraines.

Simpesse should not be used by women with a high risk of blood clots, known or suspected breast or other estrogen-dependent cancer, undiagnosed abnormal uterine bleeding, liver tumors or active liver disease, uncontrolled high blood pressure, diabetes with vascular disease, migraine with aura, during pregnancy, or while taking hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir. Certain medicines, including some anti-seizure drugs, rifampin, and St. John's Wort, can make it less effective. Simpesse does not protect against HIV or other sexually transmitted infections. This is not medical advice; talk with your doctor or pharmacist about whether Simpesse is right for you.