Tamoxifen Citrate
Tamoxifen Citrate 20MG
What is Tamoxifen Citrate?
Tamoxifen Citrate is a non-steroidal selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of breast cancer. It functions by binding to estrogen receptors in breast tissue, blocking the hormone's ability to promote cancer growth. Commonly prescribed under the brand name Nolvadex, Tamoxifen is also used to manage other hormone-responsive cancers and certain gynecological conditions.Side Effects
- Pain in your lower leg (calf)
- Numbness or weakness in your arm or leg, or on one side of your body
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Warnings
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: abdominal pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin.
- Swelling in your hands, ankles, or feet.
- Unusual bleeding, bruising, or weakness.
- Yellowing of your skin or the whites of your eyes.
Prescription savings · · · ·
What is Tamoxifen Citrate ?
Tamoxifen Citrate is a non-steroidal selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of breast cancer. It functions by binding to estrogen receptors in breast tissue, blocking the hormone's ability to promote cancer growth. Commonly prescribed under the brand name Nolvadex, Tamoxifen is also used to manage other hormone-responsive cancers and certain gynecological conditions.- Pain in your lower leg (calf)
- Numbness or weakness in your arm or leg, or on one side of your body
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blurred vision or other change in vision
- Chest pain, trouble breathing, coughing up blood
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Fever, chills, cough, sore throat, body aches
- Heavy or abnormal vaginal bleeding, pelvic pain or pressure, vaginal discharge
- New breast lumps
- Unusual bleeding, bruising, or weakness
- Swelling in your hands, ankles, or feet
- Sudden or severe headache, problems with vision, speech, or walking
- Yellowing of your skin or the whites of your eyes.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Liver problems may occur while you are using this medicine. Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: abdominal pain or tenderness; clay-colored stools; dark urine; decreased appetite; fever; headache; itching; loss of appetite; nausea and vomiting; skin rash; swelling of the feet or lower legs; unusual tiredness or weakness; or yellow eyes or skin.
- Swelling in your hands, ankles, or feet.
- Unusual bleeding, bruising, or weakness.
- Yellowing of your skin or the whites of your eyes.
- Make sure any doctor or dentist who treats you knows that you are using this medicine.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. It is also important for women to have regular gynecologic check-ups while using this medicine.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- This medicine may cause the following problems:Increased risk for other cancers, including endometrium, liver, or uterus cancerBlood clotsEye or vision problems
- Tell your doctor if you have liver disease, eye or vision problems (including cataracts), high cholesterol (fat) in the blood, or a history of stroke.
- Oral routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Birth control pills may not work as well to prevent pregnancy when used with this medicine. Use another form of birth control (including condoms or spermicide) along with your pills during treatment with this medicine and for 2 months after the last dose.
- Do not breastfeed during treatment with this medicine and for 3 months after the last dose.
- Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
Tamoxifen Citrate Coupons & Prices
Tamoxifen Citrate 20MG
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Looking for a tamoxifen citrate coupon? Tamoxifen is an FDA-approved generic medicine, so it is already one of the lower-cost breast cancer treatments. Even so, the cash price can vary widely from one pharmacy to the next, which is why comparing before you fill matters. Enter your ZIP above to see today's tamoxifen citrate price and a free Rx.com discount coupon accepted at more than 60,000 U.S. pharmacies. There is no insurance required, and the coupon can be used whether or not you have coverage.
What is tamoxifen citrate and how does it work?
Tamoxifen citrate is a selective estrogen receptor modulator (SERM), a nonsteroidal antiestrogen that blocks the effect of estrogen in breast tissue. Because many breast cancers grow in response to estrogen, tamoxifen is used to treat and help prevent these cancers. It is FDA-approved to treat metastatic breast cancer in women and men; as adjuvant (after-surgery) treatment for node-positive and node-negative breast cancer; to reduce the risk of a second (contralateral) breast cancer; to lower the risk of invasive breast cancer in women with ductal carcinoma in situ (DCIS) after surgery and radiation; and to reduce breast cancer incidence in women at high risk.
Tamoxifen is taken by mouth. It is available as a generic tablet and as a branded oral solution, Soltamox, which can help people who have trouble swallowing pills. Your care team will decide the right form and length of treatment for your situation.
How much does tamoxifen citrate cost without insurance?
Tamoxifen is an established generic, so it is generally affordable compared with brand-name cancer therapies. That said, cash prices are not the same everywhere: two pharmacies in the same town can charge very different amounts for the exact same prescription. Because of that spread, comparing prices is the single easiest way to save. Enter your ZIP above to see today's price at pharmacies near you and to pull up a free Rx.com discount coupon accepted at more than 60,000 pharmacies nationwide.
The branded oral solution Soltamox has its own manufacturer patient-access program; you can look it up on the official Soltamox website. Program terms and eligibility vary and can change, so check the current details there. For most people filling the generic tablet, an Rx.com cash coupon is the simplest route, and you can compare that price against your insurance copay to see which is lower.
Tamoxifen alternatives and related medicines
Tamoxifen is one of several hormone-based options for breast cancer treatment and risk reduction. The best choice depends on menopausal status, tumor type, and your overall health, so this is a conversation for you and your oncologist. Related medicines you may see include:
- anastrozole, letrozole, and exemestane — aromatase inhibitors typically used in postmenopausal women
- raloxifene — another SERM used to reduce breast cancer risk in some postmenopausal women (and for osteoporosis)
- Soltamox — the branded liquid form of tamoxifen for people who cannot swallow tablets
You can compare cash prices for any of these on Rx.com to see which is most affordable at your pharmacy. The former brand tablet Nolvadex is no longer marketed in the U.S.; the generic tablet is the standard tamoxifen product today.
Safety, warnings, and side effects
Tamoxifen carries an FDA boxed warning about serious and sometimes fatal events, including uterine cancers (endometrial adenocarcinoma and uterine sarcoma), stroke, and blood clots in the lung (pulmonary embolism). For women taking it to lower breast cancer risk, the benefits and risks should be weighed carefully with a doctor. Report any abnormal vaginal bleeding or gynecologic symptoms promptly, and keep up with recommended annual gynecologic exams.
Tamoxifen can cause fetal harm and must not be used in pregnancy; effective non-hormonal contraception is required. Other possible effects include hot flashes, vaginal discharge, menstrual changes, cataracts or vision changes, elevated liver enzymes (rarely more serious liver problems), high blood calcium, and bone loss in premenopausal women. Because tamoxifen is processed by the CYP2D6 enzyme, certain strong CYP2D6-inhibiting antidepressants (some SSRIs) may reduce how well it works, and combining it with warfarin can increase bleeding risk. This is general information, not medical advice — review all of your medicines with your prescriber or pharmacist.
This Tamoxifen Citrate information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Tamoxifen Citrate on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.