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Velphoro Tablet Chewable — prescription drug image

Velphoro

Velphoro 500MG

Prescriptions & Refills
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What is Velphoro?

Velphoro is used to reduce high levels of phosphorous in the blood of patients with severe kidney disease. Velphoro is a brand name of sucroferric oxyhydroxide. On average Velphoro is priced at about $1,089 for a supply of 90, 2500 mg (500 mg elemental iron) chewable tablets. Luckily, you can use our Rx.com savings offer to receive a Velphoro discount of up to 80% off the retail price at participating pharmacies near you.

Prescription savings · · · ·

What is Velphoro ?

Velphoro is used to reduce high levels of phosphorous in the blood of patients with severe kidney disease. Velphoro is a brand name of sucroferric oxyhydroxide. On average Velphoro is priced at about $1,089 for a supply of 90, 2500 mg (500 mg elemental iron) chewable tablets. Luckily, you can use our Rx.com savings offer to receive a Velphoro discount of up to 80% off the retail price at participating pharmacies near you.
  • Diarrhea, nausea
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • This medicine may discolor your stools black. This is normal and nothing to worry about.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, stomach or digestive problems, or a history of hemochromatosis (too much iron in the blood). Tell your doctor if you have had surgery on your stomach or digestive system.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is Velphoro used for?
Velphoro (sucroferric oxyhydroxide) is an iron-based phosphate binder that controls high phosphorus levels (hyperphosphatemia) in adults and children 9 years and older who have chronic kidney disease and are on dialysis. It binds phosphate from food so less is absorbed into the blood.
Is there a generic version of Velphoro?
No. There is currently no generic version of Velphoro; only the brand-name chewable tablet is available. Because there is no lower-cost generic, a free Rx.com cash coupon is one of the main ways to reduce the out-of-pocket price. Enter your ZIP above to see today's price.
Why does Velphoro turn your stool black?
Velphoro contains iron, and iron commonly darkens the stool. Black or discolored stool is an expected, harmless effect of the medicine. Still, if you notice black stools along with other symptoms or feel unwell, let your provider know.
How and when should you take Velphoro?
Take Velphoro with meals, following the schedule your prescriber gives you. The chewable tablets must be chewed, or crushed if needed, and should not be swallowed whole. Some oral medicines, such as levothyroxine and doxycycline, may need to be taken at a separate time because Velphoro can reduce their absorption.
How much does Velphoro cost without insurance?
The cash price varies by pharmacy and location, and there is no generic to lower it. A free Rx.com cash coupon can reduce what you pay whether you are uninsured or on Medicare. Enter your ZIP above to see today's price at pharmacies near you, and compare it against any manufacturer savings card you may qualify for.
How much does Velphoro cost without insurance?
The price of Velphoro without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Velphoro?
Common side effects of Velphoro may include: Diarrhea, nausea, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Velphoro?
Generic versions may be available for Velphoro. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Velphoro on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Velphoro?
The cheapest pharmacy for Velphoro depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Velphoro near you.

Velphoro Coupons & Prices

Velphoro 500MG

Prescriptions & Refills
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Velphoro Tablet Chewable — prescription drug image
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Looking for a Velphoro coupon? Velphoro (sucroferric oxyhydroxide) is an iron-based phosphate binder chewable tablet used to control high phosphorus levels (hyperphosphatemia) in adults and children 9 and older with chronic kidney disease who are on dialysis. Because there is no generic version yet, the price can be a concern for many families. A free Rx.com cash coupon can lower what you pay at the pharmacy counter, whether or not you have insurance. Enter your ZIP above to see today's price at pharmacies near you.

What is Velphoro and how does it work?

Velphoro (sucroferric oxyhydroxide) is an iron-based phosphate binder. It is FDA-approved to control serum phosphorus levels in adult and pediatric patients 9 years and older who have chronic kidney disease (CKD) and are on dialysis. When your kidneys cannot remove enough phosphorus, it can build up in the blood; Velphoro binds to phosphate from the food you eat so that it passes out of the body instead of being absorbed.

Velphoro comes as a chewable tablet and is taken with meals. The tablets must be chewed (or crushed if needed) and should not be swallowed whole. Always follow the dosing and schedule your prescriber and dialysis team give you.

Velphoro cost and savings: manufacturer card vs. Rx.com cash coupon

The maker of Velphoro offers an official manufacturer savings program (you can find it by searching for the Velphoro savings card on the manufacturer's website). Manufacturer copay cards like this are generally limited to people with commercial (private) insurance, and the terms, eligibility, and any limits vary and can change. They typically cannot be used if you are uninsured or covered by Medicare, Medicaid, or another government program.

That is where a free Rx.com cash coupon helps. It is a cash-price discount, so it works whether you are uninsured, on Medicare, or find that the manufacturer card is declined at the counter. You cannot combine a cash coupon with insurance on the same purchase, but you can compare both and use whichever is lower. Because Velphoro has no generic, the cash coupon is one of the main ways to trim the out-of-pocket price today. If cost is still a burden, ask your dialysis social worker or the manufacturer whether a patient assistance program is available. Enter your ZIP above to see today's price near you.

Velphoro alternatives and other phosphate binders

Velphoro is one of several phosphate binders used to manage high phosphorus in dialysis patients. Your nephrologist chooses a binder based on your phosphorus and calcium levels, pill burden, and how well you tolerate it. Other options your care team may discuss include:

  • Renvela and Renagel (sevelamer) — calcium-free, non-iron binders
  • Fosrenol (lanthanum carbonate) — a chewable, calcium-free binder
  • Auryxia (ferric citrate) — another iron-based binder
  • PhosLo (calcium acetate) — a calcium-based binder

These are not interchangeable, and switching binders is a decision for your prescriber. If you are prescribed one of them, you can look up its price and coupon on its Rx.com page. This is general information, not medical advice.

Velphoro safety and side effects

Velphoro has no boxed warning. The most common side effects are discolored or black stool, diarrhea, and nausea. Black stool is expected with an iron-based product and is generally harmless, but tell your provider if it comes with other symptoms. Because Velphoro contains iron, use caution if you have an iron-accumulation disorder such as hemochromatosis or a significant stomach or bowel disorder; it has not been studied in people with peritonitis, major gastric or liver disorders, or recent gastrointestinal surgery. If you also receive IV iron or an erythropoiesis-stimulating agent (ESA), your team may monitor your iron levels.

Velphoro can reduce how well your body absorbs some oral medicines, such as levothyroxine and doxycycline, so those may need to be taken at a separate time. Take Velphoro with meals and chew (or crush) the tablets rather than swallowing them whole. This is not medical advice — always review your full medication list and any questions with your doctor or pharmacist.

Sources & accuracy

This Velphoro information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Velphoro on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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