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Ziprasidone Hcl Capsule — prescription drug image

Ziprasidone Hcl

Ziprasidone HCl 40MG

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What is Ziprasidone Hcl?

Geodon is an antipsychotic medication used to treat mental disorders, such as schizophrenia and bipolar disorder. Ziprasidone is the generic version of Geodon. On average, Geodon is priced at about $1,412 for a supply of 60, 80 mg capsules. You can use our Rx.com savings offer to get an average Geodon discount of up to 80% off of the retail price at participating pharmacies near you.

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What is Ziprasidone Hcl ?

Geodon is an antipsychotic medication used to treat mental disorders, such as schizophrenia and bipolar disorder. Ziprasidone is the generic version of Geodon. On average, Geodon is priced at about $1,412 for a supply of 60, 80 mg capsules. You can use our Rx.com savings offer to get an average Geodon discount of up to 80% off of the retail price at participating pharmacies near you.
  • Twitching or muscle movements you cannot control (especially in your face, tongue, or jaw)
  • Painful, prolonged erection of your penis
  • Fever, sweating, confusion, muscle stiffness, seizures
  • Lightheadedness, dizziness, or fainting
  • Unusual bleeding, bruising, or weakness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Chills, cough, sore throat, and body aches
  • Fast, slow, pounding, or uneven heartbeat
  • Fever, skin rash, or swollen glands in your armpits, neck, or groin
  • Increased thirst, hunger, or urination
  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, blood or bone marrow problems, diabetes, high cholesterol, trouble swallowing, or a history of seizures or breast cancer. Tell your doctor if you have heart rhythm problems (such as QT prolongation) or any heart or blood vessel problems, including low blood pressure, heart failure, or a history of a heart attack.
  • This medicine may cause the following problems:Heart rhythm problemsNeuroleptic malignant syndrome (possibly life-threatening neurological disorder)Drug reaction with eosinophilia and systemic symptoms (DRESS), which can damage organs such as the liver, kidney, or heartSerious skin reactionsTardive dyskinesia (trouble controlling muscle movements)
  • This medicine may make you dizzy or drowsy, or may cause trouble with thinking or controlling body movements, which may lead to falls, fractures, or other injuries. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you feel lightheaded or dizzy.
  • You may get overheated more easily while you are using this medicine. Use caution when you exercise strenuously or are outside in hot weather. Drink plenty of water to stay hydrated.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
  • Increased thirst, hunger, or urination
  • Lightheadedness, dizziness, or fainting
  • Painful, prolonged erection of your penis
  • Twitching or muscle movements you cannot control (especially in your face, tongue, or jaw)
  • Unusual bleeding, bruising, or weakness
What is ziprasidone (Geodon) used for?
Ziprasidone is an atypical antipsychotic. The oral capsules are FDA-approved to treat schizophrenia, to treat acute manic or mixed episodes of bipolar I disorder on their own, and as an add-on to lithium or valproate for the ongoing (maintenance) treatment of bipolar I disorder. A separate injectable form is used in medical settings for acute agitation in people with schizophrenia.
What are the most common side effects of ziprasidone?
Common side effects include drowsiness, dizziness (sometimes when standing up), restlessness, nausea, constipation, and muscle stiffness or movement changes. More serious but less common risks include heart-rhythm (QT) changes, neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes such as high blood sugar or weight gain, and severe skin reactions. Tell your doctor about any fainting, fast or irregular heartbeat, high fever with muscle rigidity, or a painful lasting erection right away.
Why does ziprasidone need to be taken with food?
Food is needed for the body to absorb ziprasidone properly. Taking it with a meal of at least about 500 calories helps ensure you get a reliable, consistent amount of the medicine. Taking it on an empty stomach can lower how much is absorbed, which may make it work less well. Try to take your doses with meals at consistent times.
Is ziprasidone a controlled substance?
No. Ziprasidone is not a controlled substance and is not scheduled by the DEA. It is a prescription-only antipsychotic, so you still need a prescription from your provider, but it does not carry the extra dispensing restrictions that apply to controlled medicines.
How is ziprasidone different from other antipsychotics like risperidone or quetiapine?
All three are atypical antipsychotics, but they differ in their side-effect profiles. Ziprasidone generally has less impact on weight and metabolism than some alternatives, but it is more likely to affect the heart's QT interval and it must be taken with food to be absorbed well. Risperidone and quetiapine have their own patterns of side effects. The best choice depends on your diagnosis and health history, so this is a decision to make with your prescriber.
How much does Ziprasidone Hcl cost without insurance?
The price of Ziprasidone Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Ziprasidone Hcl?
Common side effects of Ziprasidone Hcl may include: Twitching or muscle movements you cannot control (especially in your face, tongue, or jaw), Painful, prolonged erection of your penis, Fever, sweating, confusion, muscle stiffness, seizures, Lightheadedness, dizziness, or fainting, Unusual bleeding, bruising, or weakness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Ziprasidone Hcl?
Generic versions may be available for Ziprasidone Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Ziprasidone Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Ziprasidone Hcl?
The cheapest pharmacy for Ziprasidone Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Ziprasidone Hcl near you.

Ziprasidone Hcl Coupons & Prices

Ziprasidone HCl 40MG

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Ziprasidone Hcl Capsule — prescription drug image
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Looking for a ziprasidone HCl (ziprasidone hydrochloride) coupon? Ziprasidone is the generic form of Geodon, an atypical (second-generation) antipsychotic taken as oral capsules for schizophrenia and bipolar I disorder. Because it is available as an FDA-approved generic, it is already one of the lower-cost options in its class, but the cash price can still swing widely from one pharmacy to the next. Rx.com compares prices across more than 60,000 U.S. pharmacies so you can find today's lowest price near you. Enter your ZIP above to see the current price and print or text yourself a free discount coupon.

What is ziprasidone HCl and how does it work?

Ziprasidone hydrochloride is an atypical (second-generation) antipsychotic. It is FDA-approved to treat schizophrenia; as a stand-alone (monotherapy) treatment for acute manic or mixed episodes of bipolar I disorder; and as an add-on to lithium or valproate for the maintenance treatment of bipolar I disorder. Like other medicines in its class, it is thought to work by rebalancing dopamine and serotonin activity in the brain, which can help ease symptoms such as hallucinations, disordered thinking, and mood swings.

The oral capsule is the everyday form and is the generic equivalent of Geodon. There is also a separate intramuscular injection (ziprasidone mesylate, a different salt) that clinicians use in a medical setting for acute agitation in people with schizophrenia. It is important to take ziprasidone capsules with a meal of at least roughly 500 calories, because food is needed for the body to absorb the drug reliably.

Ziprasidone cost and savings without insurance

Because a substitutable generic is on the market, ziprasidone is typically far cheaper than the brand and is considered an affordable choice within the antipsychotic class. Even so, the cash price is not fixed. Different pharmacies set very different prices for the exact same capsules, so it genuinely pays to compare before you fill. There is no manufacturer copay or savings card for generic ziprasidone; a free discount coupon is usually the most useful tool if you are paying without insurance or your plan does not cover it.

Rx.com checks prices across more than 60,000 pharmacies and shows you the lowest one nearby. Enter your ZIP above to see today's price and get a free coupon you can print or have texted to you. Prices update over time and by location, so it is worth checking each time you refill.

Ziprasidone vs. other antipsychotics

Ziprasidone is one of several atypical antipsychotics, and each has a somewhat different balance of benefits and side effects. Compared with some others in the class, ziprasidone tends to have less effect on weight and metabolism, but it is more likely to affect the heart's QT interval and it must be taken with food. Your prescriber chooses among these based on your diagnosis, other health conditions, and how you respond.

If you were prescribed the brand, you can also compare the price of Geodon. Only your provider should decide whether to switch medicines; use these links to compare pricing, not to self-adjust treatment.

Important safety information

Ziprasidone carries a boxed warning that elderly patients with dementia-related psychosis treated with antipsychotics have an increased risk of death; it is not approved for that use. Ziprasidone is notable for prolonging the heart's QT interval more than most other atypical antipsychotics. For that reason it should not be used by people with a known history of QT prolongation, a recent heart attack, or uncompensated heart failure, or together with other medicines that prolong the QT interval; low potassium or magnesium levels should be corrected first.

Other possible risks include neuroleptic malignant syndrome, tardive dyskinesia, metabolic changes (high blood sugar or new diabetes, cholesterol changes, weight gain), a drop in blood pressure on standing, drowsiness, severe skin or allergic reactions (including DRESS), prolonged painful erections (priapism), and trouble regulating body temperature. Remember to take each dose with food. This is a general summary and not medical advice; talk with your doctor or pharmacist about your full health history and any other medicines you take.

Sources & accuracy

This Ziprasidone Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Ziprasidone Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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