Cyclosporine Coupons & Prices

Looking for a cyclosporine coupon? Cyclosporine is a widely used generic immunosuppressant, which means it is already far less expensive than brand-name versions like Neoral, Gengraf, or Sandimmune. Even so, the cash price can vary a lot from one pharmacy to the next, so it pays to compare before you fill. Enter your ZIP above to see today's cyclosporine price and a free Rx.com discount coupon accepted at more than 60,000 U.S. pharmacies.

What is cyclosporine and how does it work?

Cyclosporine is a calcineurin inhibitor immunosuppressant. It works by calming down part of the immune system so the body reacts less strongly. In transplant patients, this helps prevent the immune system from attacking (rejecting) a newly transplanted kidney, liver, or heart, and it is usually given together with corticosteroids. It is also FDA-approved to treat severe active rheumatoid arthritis that has not responded well enough to methotrexate, and severe hard-to-treat plaque psoriasis in adults who have failed other systemic therapies.

Cyclosporine comes as oral capsules and liquid for whole-body (systemic) use, and as prescription eye drops (Restasis, Cequa, Vevye, Verkazia) used for chronic dry eye disease and certain eye conditions. One important note: the "modified" oral forms (Neoral, Gengraf) and the "non-modified" form (Sandimmune) are absorbed differently and are not interchangeable. This is not medical advice; your prescriber and pharmacist will confirm exactly which formulation is right for you.

How much does cyclosporine cost without insurance?

Because cyclosporine is available as a generic, it is generally one of the lower-cost immunosuppressants, but "low cost" still depends heavily on where you fill it. Two pharmacies in the same town can charge noticeably different cash prices for the exact same generic capsule or eye drop, which is why comparing matters. If you do not have insurance, or your plan does not cover your formulation well, a free discount coupon can help you pay the cash price.

Rx.com compares cyclosporine prices across more than 60,000 pharmacies so you can find a lower price near you. Enter your ZIP above to see today's price for your specific strength and formulation, then show the coupon at the pharmacy counter. There is no membership or fee to use it.

Cyclosporine alternatives and related medications

Cyclosporine is one of several immunosuppressants a specialist may consider, depending on the condition being treated. Only your prescriber can decide what is appropriate, but medications commonly discussed alongside it include:

• tacrolimus — another calcineurin inhibitor
• mycophenolate and azathioprine — often used together with, or in place of, cyclosporine in transplant regimens
• sirolimus — an mTOR inhibitor immunosuppressant
• methotrexate — used for rheumatoid arthritis and psoriasis
• prednisone — a corticosteroid frequently paired with cyclosporine after transplant

If you use cyclosporine eye drops for dry eye, see our Restasis page for the brand version. Whichever medication you are prescribed, you can compare its price on Rx.com by searching its name.

Cyclosporine safety and warnings

Cyclosporine carries boxed warnings and should be managed by a prescriber experienced in immunosuppressive therapy. Because it lowers immune activity, it can increase the risk of serious infections and of certain cancers, especially skin cancer and lymphoma. In psoriasis and rheumatoid arthritis patients, previous treatment with PUVA, UVB, methotrexate, other immunosuppressants, coal tar, or radiation can raise skin cancer risk further. Other important risks include dose-related kidney effects (nephrotoxicity), high blood pressure, and liver effects.

Common side effects can include tremor, increased hair growth, gum overgrowth, high potassium, and high cholesterol. Cyclosporine also interacts with many drugs through the CYP3A4 and P-glycoprotein pathways, so you should avoid grapefruit juice and live vaccines and give your doctor a full list of your medicines and supplements. This page is general information, not medical advice. Do not start, stop, or change your dose without talking to your healthcare provider.