Azathioprine
azaTHIOprine 50MG
What is Azathioprine?
Azathioprine is a medication used to help prevent the body from rejecting a transplanted kidney and to treat severe rheumatoid arthritis when other treatments have not worked.
Side Effects
- Sores on the skin, swollen glands, abnormal skin growths
- Unusual bleeding, bruising, or weakness
- Severe stomach pain, nausea, vomiting, or diarrhea
Warnings
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, stomach or bowel problems (including Crohn's disease, ulcerative colitis), blood or bone marrow problems, or any type of infection.
- This medicine may cause the following problems:Increased risk of cancer (including skin cancer, solid tumor, leukemia, or lymphoma)Increased risk of infection, including progressive multifocal leukoencephalopathy (PML)Serious bowel allergic reactions
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Prescription savings · · · ·
What is Azathioprine ?
Azathioprine is a medication used to help prevent the body from rejecting a transplanted kidney and to treat severe rheumatoid arthritis when other treatments have not worked.
- Sores on the skin, swollen glands, abnormal skin growths
- Unusual bleeding, bruising, or weakness
- Severe stomach pain, nausea, vomiting, or diarrhea
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Fever, chills, cough, sore throat, body aches
- Lightheadedness, dizziness, or fainting
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, stomach or bowel problems (including Crohn's disease, ulcerative colitis), blood or bone marrow problems, or any type of infection.
- This medicine may cause the following problems:Increased risk of cancer (including skin cancer, solid tumor, leukemia, or lymphoma)Increased risk of infection, including progressive multifocal leukoencephalopathy (PML)Serious bowel allergic reactions
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- Use sunscreen with a sun protection factor (SPF) of at least 15 when you are outdoors. Wear protective clothing and hats, and stay out of direct sunlight between the hours of 10 am and 3 pm Avoid sunlamps and tanning beds.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Azathioprine Coupons & Prices
azaTHIOprine 50MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Azathioprine prices by dosage
Lowest cash price with a free Rx.com coupon vs. the average retail price.
| Dosage | Quantity | Retail price | Rx.com price |
|---|---|---|---|
| 50mg · Tablet | 30 | $41.79 | $14.88 |
| 75mg · Tablet | 30 | $355.29 | $149.67 |
| 100mg · Tablet | 30 | $363.59 | $64.52 |
Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.
Looking for an azathioprine coupon? Azathioprine is the low-cost generic version of the brand-name drugs Imuran and Azasan, an immunosuppressant used to help prevent kidney transplant rejection and to treat severe rheumatoid arthritis. Because it is a generic, the cash price is usually modest, but it can still vary widely from one pharmacy to another. Enter your ZIP code above to compare today's azathioprine prices across more than 60,000 pharmacies and print or show a free Rx.com coupon at the pharmacy counter.
What is azathioprine and how does it work?
Azathioprine is an immunosuppressant in the purine antimetabolite class. It works by dampening the activity of the body's immune system, which lowers the chance that the immune system will attack a transplanted organ or the body's own tissues. It is FDA-approved to help prevent rejection in people who have received a kidney (renal) transplant and to treat severe, active rheumatoid arthritis that has not responded to other standard treatments.
Doctors also prescribe azathioprine for a number of other immune-related conditions. Azathioprine is taken by mouth, usually once or twice daily, and it typically takes time to reach its full effect. Your prescriber will decide the right dose and monitoring plan for your situation.
Azathioprine cost and coupons without insurance
Azathioprine is available as a generic, which usually makes it one of the more affordable immunosuppressants to fill. Even so, the cash price is not the same everywhere. Two pharmacies in the same town can charge noticeably different amounts for the identical tablets, which is exactly why comparing before you fill is worth it. The brand-name versions, Imuran and Azasan, are typically more expensive than the generic.
Rx.com compares live azathioprine prices across more than 60,000 U.S. pharmacies so you can see who is cheapest near you. There is no manufacturer copay card for generic azathioprine, but our discount coupon is free to use whether or not you have insurance. Enter your ZIP code above to see today's price and get your coupon.
Azathioprine alternatives and related drugs
Azathioprine is closely related to mercaptopurine (the two are metabolized along the same pathway). Depending on the condition being treated, prescribers may consider other immunosuppressants such as methotrexate, mycophenolate, tacrolimus, or cyclosporine. Each works differently and has its own monitoring needs.
Only your doctor can decide which medicine is right for you. If cost is a factor, you can compare prices for these alternatives on Rx.com and discuss the options with your prescriber. Never switch or stop an immunosuppressant on your own.
Important safety information
Azathioprine carries a boxed warning: long-term immune suppression can raise the risk of certain cancers, including skin cancers and lymphoma. It can also lower blood cell counts (bone marrow suppression), which is why regular blood tests are required. People with reduced TPMT or NUDT15 enzyme activity are at higher risk, and testing for these is recommended before or during treatment. Azathioprine also increases the chance of serious infections and can affect the liver.
Tell your provider about every medicine you take. Combining azathioprine with allopurinol or febuxostat (gout medicines) requires a major dose reduction and can be dangerous otherwise, and drugs such as ACE inhibitors, trimethoprim-sulfamethoxazole, and ribavirin can worsen its effect on blood counts. Live vaccines should be avoided. This information is a summary and is not medical advice; talk with your doctor or pharmacist about your personal risks and monitoring plan.
This Azathioprine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Azathioprine on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.