Desloratadine
Desloratadine 5MG
What is Desloratadine?
Clarinex is used to treat allergic rhinitis. The generic version of Clarinex is Desloratadine. The average price for Clarinex is around $269 for a supply of 30, 5 mg tablets. Use our Rx.com savings offer to get big discounts on Clarinex at participating pharmacies near you.Side Effects
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Fast or irregular (uneven) heartbeat.
- Pain when urinating, or trouble urinating.
Warnings
- Pain when urinating, or trouble urinating.
- Some forms of this medicine may contain phenylalanine (aspartame). Read the label before using this medicine. This is only a concern if you have a disorder called phenylketonuria (a problem with amino acids). If you have this condition, talk to your doctor before using this medicine.
- Make sure your doctor knows if you are pregnant or breast feeding, or if you have liver disease or kidney disease. Tell your doctor if you have a history of heart problems, and about any other medical problems you may have.
- Yellowing of your skin or the whites of your eyes.
Prescription savings · · · ·
What is Desloratadine ?
Clarinex is used to treat allergic rhinitis. The generic version of Clarinex is Desloratadine. The average price for Clarinex is around $269 for a supply of 30, 5 mg tablets. Use our Rx.com savings offer to get big discounts on Clarinex at participating pharmacies near you.- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Fast or irregular (uneven) heartbeat.
- Pain when urinating, or trouble urinating.
- Mild skin rash.
- Muscle aches.
- Yellowing of your skin or the whites of your eyes.
- Pain when urinating, or trouble urinating.
- Some forms of this medicine may contain phenylalanine (aspartame). Read the label before using this medicine. This is only a concern if you have a disorder called phenylketonuria (a problem with amino acids). If you have this condition, talk to your doctor before using this medicine.
- Make sure your doctor knows if you are pregnant or breast feeding, or if you have liver disease or kidney disease. Tell your doctor if you have a history of heart problems, and about any other medical problems you may have.
- Yellowing of your skin or the whites of your eyes.
Desloratadine Coupons & Prices
Desloratadine 5MG
Weight-loss medication, prescribed online
Licensed U.S. providers · No insurance needed · Shipped to your door
Looking for a desloratadine coupon? Desloratadine is the low-cost generic version of Clarinex, a once-daily, non-drowsy antihistamine used for seasonal and year-round allergies and chronic hives. Because it is a generic, the cash price is already modest, but what you actually pay can vary widely from one pharmacy to the next. Rx.com compares desloratadine prices across more than 60,000 pharmacies so you can find the lowest price near you and show a free discount coupon at the counter. Enter your ZIP above to see today's price.
What is desloratadine and how does it work?
Desloratadine is a second-generation, non-sedating H1 antihistamine and is the active metabolite of loratadine. It is sold under the brand name Clarinex, and Clarinex-D combines desloratadine with the decongestant pseudoephedrine. It works by blocking histamine, the natural substance your body releases during an allergic reaction, which helps calm sneezing, runny nose, itchy or watery eyes, and an itchy nose or throat.
The FDA has approved desloratadine to relieve the nasal and non-nasal symptoms of seasonal allergic rhinitis in patients 2 years and older, and of perennial (year-round) allergic rhinitis in patients 6 months and older. It is also approved to relieve itching and reduce hives in chronic idiopathic urticaria in patients 6 months and older. It is taken once daily. Clarinex-D is used when allergy symptoms come with nasal congestion.
How much does desloratadine cost without insurance?
Desloratadine is available as an FDA-approved generic, so it is generally one of the more affordable prescription allergy options, even if you are paying cash without insurance. The catch is that pharmacies set their own cash prices, and the difference between the highest and lowest price in the same town can be surprisingly large. That is why it pays to compare before you fill.
Rx.com checks desloratadine prices across more than 60,000 U.S. pharmacies and gives you a free discount coupon you can use whether or not you have insurance. There is no manufacturer savings card for desloratadine, so a pharmacy discount is usually the most reliable way to lower the cash price. Enter your ZIP above to see today's price near you.
Desloratadine vs. other antihistamines
Desloratadine is one of several non-drowsy, once-daily antihistamines, and the best choice often comes down to price and how your body responds. If desloratadine is not covered or not the cheapest option at your pharmacy, it is worth comparing prices on these related allergy medicines:
- Loratadine (Claritin) - the parent drug that your body converts into desloratadine
- Cetirizine (Zyrtec)
- Levocetirizine (Xyzal)
- Fexofenadine (Allegra)
- Montelukast (Singulair), a non-antihistamine option for allergic rhinitis
All of these are available as generics. Use the ZIP search above to compare the cash price of each and find the best value for you.
Safety and side effects
Desloratadine is generally well tolerated and has no boxed warning. The most common side effects are headache, dry mouth, fatigue, drowsiness, nausea, dizziness, and sore throat. Rare hypersensitivity reactions such as rash, itching, hives, swelling (angioedema), and anaphylaxis have been reported; get medical help right away if you notice signs of a serious allergic reaction. An overdose most often shows up as drowsiness.
If you have liver or kidney problems, your provider may recommend every-other-day dosing. The orally disintegrating tablets contain aspartame (a source of phenylalanine), which matters if you have phenylketonuria. Use caution during pregnancy or breastfeeding. This information is not medical advice, so talk with your doctor or pharmacist about your full health history and any other medicines you take before starting desloratadine.
This Desloratadine information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Desloratadine on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.