Impact-Site-Verification: 2721d812-1059-4270-b9fa-5c1654788cd1

GLP-1 Weight Loss $146/mo · No insurance needed GLP-1 Weight Loss $146/mo See if I qualify → ED Treatment · Prescribed online ED Treatment Get started →
Levothyroxine Sodium Tablet — prescription drug image

Levothyroxine Sodium

Levothyroxine Sodium 50MCG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Get a Prescription Track prices See prices near you

What is Levothyroxine Sodium?

Levothyroxine Sodium is a synthetic form of the thyroid hormone thyroxine, used primarily in the treatment of hypothyroidism to restore normal metabolic activity. By supplementing low levels of natural thyroid hormone, it helps regulate energy and metabolism, alleviating symptoms such as fatigue, weight gain, and depression. It's also used to prevent goiter and manage certain types of thyroid cancer, provided under careful medical supervision to achieve the desired hormonal balance.

Prescription savings · · · ·

What is Levothyroxine Sodium ?

Levothyroxine Sodium is a synthetic form of the thyroid hormone thyroxine, used primarily in the treatment of hypothyroidism to restore normal metabolic activity. By supplementing low levels of natural thyroid hormone, it helps regulate energy and metabolism, alleviating symptoms such as fatigue, weight gain, and depression. It's also used to prevent goiter and manage certain types of thyroid cancer, provided under careful medical supervision to achieve the desired hormonal balance.
  • Increased appetite
  • Weight loss
  • Heat intolerance
  • Excessive sweating
  • Headache
  • Nervousness
  • Anxiety
  • Irritability
  • Insomnia
  • Fever
  • Changes in menstrual periods
  • Sensitivity to heat
  • Temporary hair loss
  • Levothyroxine Sodium should not be used for weight loss or obesity treatment.
  • Overdose can cause hyperthyroidism symptoms and serious cardiovascular issues.
  • Use with caution in patients with cardiovascular disease, including angina and hypertension.
  • Initial doses should be low in elderly patients and those with severe hypothyroidism or other conditions affecting the heart.
  • Regular monitoring of thyroid hormone levels is recommended during treatment.
  • Inform healthcare providers of all medications being taken as Levothyroxine Sodium can interact with other drugs.
  • Not indicated for treatment of infertility unless associated with hypothyroidism.
  • Avoid sudden discontinuation of therapy.
What is levothyroxine sodium used for? ▼
Levothyroxine sodium is used to treat hypothyroidism (an underactive thyroid) by replacing or supplementing the T4 hormone your body normally makes. It is also used alongside surgery and radioiodine to help manage certain well-differentiated thyroid cancers by suppressing TSH, and to treat or prevent certain goiters, including thyroid nodules and Hashimoto's thyroiditis. It is not approved for weight loss or obesity.
What are the most common side effects of levothyroxine? ▼
Most side effects come from getting too much hormone and look like an overactive thyroid: a fast or pounding heartbeat, irregular heartbeat, tremor, trouble sleeping, feeling unusually warm or sweaty, nervousness, and unintended weight loss. Long-term over-treatment can also affect heart rhythm and bone density. If you notice these symptoms, contact your provider, who may check your TSH and adjust your dose.
Should levothyroxine be taken on an empty stomach, and how long before eating? ▼
Yes. Levothyroxine is usually taken on an empty stomach because food can reduce how well it is absorbed. Many people take it first thing in the morning and wait before eating, and keep it separated from calcium, iron, and antacids. Follow the exact timing your doctor or pharmacist gives you and take it the same way every day so your levels stay steady.
Is generic levothyroxine as effective as Synthroid? ▼
Generic levothyroxine sodium contains the same active thyroid hormone (T4) as Synthroid. However, levothyroxine has a narrow therapeutic index, so it is not always fully substitutable, and switching between a brand and a generic or between manufacturers can slightly change your TSH control. If your product changes, your provider may recheck your thyroid levels to make sure your dose is still right.
What foods, supplements, and medications should you avoid with levothyroxine? ▼
Take levothyroxine on an empty stomach and separate it from things that block its absorption, especially calcium and iron supplements and antacids. Other medications can also interact with it, so give your doctor and pharmacist a full list of everything you take, including over-the-counter products. Do not change how or when you take your other medicines without checking with them first.
What is Levothyroxine Sodium 50MCG used for? ▼
Levothyroxine sodium is the most prescribed medication in the United States — a synthetic form of the thyroid hormone thyroxine (T4) used to treat hypothyroidism (underactive thyroid) and to suppress TSH in thyroid cancer management. When the thyroid gland does not produce enough hormone, it affects nearly every organ system in the body — causing fatigue, weight gain, depression, cold intolerance, and more. It replaces the missing T4, restoring normal metabolism. Levothyroxine is taken once daily on an empty stomach (30–60 minutes before eating) for maximum absorption. Doses are highly individualized based on age, weight, TSH level, and whether thyroid cancer suppression is needed — typically ranging from 25 mcg to 200+ mcg per day. A licensed provider can order thyroid labs and prescribe levothyroxine through Rx.com for hypothyroidism management.
How much does Levothyroxine Sodium 50MCG cost without insurance? ▼
The price of Levothyroxine Sodium 50MCG without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save 60–90% off retail prices with a free Rx.com coupon.
What are the common side effects of Levothyroxine Sodium 50MCG? ▼
Common side effects of Levothyroxine Sodium 50MCG may include: Seizures or tremors, Fast, pounding, or uneven heartbeat, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Chest pain that may spread, trouble breathing, unusual sweating, fainting, Confusion, swelling of the face, tongue, or lower legs, feeling cold, unusual tiredness or weakness. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Levothyroxine Sodium 50MCG? ▼
Generic versions may be available for Levothyroxine Sodium 50MCG. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Levothyroxine Sodium 50MCG on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Levothyroxine Sodium 50MCG? ▼
The cheapest pharmacy for Levothyroxine Sodium 50MCG depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Levothyroxine Sodium 50MCG near you.

Levothyroxine Sodium Coupons & Prices

Levothyroxine Sodium 50MCG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Get a Prescription Track prices See prices near you
Levothyroxine Sodium Tablet — prescription drug image
Prescription
Levothyroxine Sodium 50mcg (90)
your area ·
QUAD by MEDVi · 4-in-1 ED treatment

4 ED medications in one dose

Sildenafil, tadalafil, vardenafil & apomorphine · Works in ~15 min · Lasts up to 36 hours

$114/mo Consult, meds & shipping included 4-in-1 formula
See QUAD by MEDVi Free online visit · No commitment
QUAD by MEDVi is a compounded prescription treatment; eligibility is determined by a licensed provider after an online visit. Pricing and product details are set by MEDVi and may change. Not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer.
Sponsored
Sesame Care — 350+ medications for $1 without insurance
📬
Order Levothyroxine Sodium Online — Home Delivery
Requires a valid prescription. Cash price only. Ships in 1–5 business days.
HealthWarehouse
HealthWarehouse
$35.10
Prices are cash prices. Insurance not accepted. Prescription required.
¿Buscando esta página en español?

Browse more medications: starting with L · full A-Z directory · by condition · common drugs

Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


Don't Miss Out On Savings!

Rx.com does not warrant the accuracy of the information on this website. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of a drug is safe, appropriate, or effective for you. Consult your healthcare professional before using any drug. All logos, brand names and trademarks on this website are the property of their respective owners. Rx.com is not endorsed or affiliated with any brands represented on this website."

Pharmacy discounts are Not Insurance, and are Not Intended as a Substitute for Insurance THE DISCOUNT IS ONLY AVAILABLE AT PARTICIPATING PHARMACIES As an Amazon Associate, we earn from qualifying purchases.

2026 All Rights Reserved | Rx.com®