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Memantine Hcl Tablet — prescription drug image

Memantine Hcl

Memantine

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What is Memantine Hcl?

Memantine is a prescription medication used to treat moderate to severe Alzheimer's disease and dementia-related cognitive decline. It works by regulating glutamate activity in the brain, which may help improve memory, thinking, and daily functioning in some patients. Learn about Memantine uses, dosage, side effects, effectiveness, and how it compares to other Alzheimer's medications. You can use the Rx.com Memantine coupon below. If you need a prescription for Memantine or refill we can see you in minutes.

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What is Memantine Hcl ?

Memantine is a prescription medication used to treat moderate to severe Alzheimer's disease and dementia-related cognitive decline. It works by regulating glutamate activity in the brain, which may help improve memory, thinking, and daily functioning in some patients. Learn about Memantine uses, dosage, side effects, effectiveness, and how it compares to other Alzheimer's medications. You can use the Rx.com Memantine coupon below. If you need a prescription for Memantine or refill we can see you in minutes.

  • Sudden or severe headache.
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate.
  • Chest pain.
  • Lightheadedness, dizziness, or fainting.
  • Seeing or hearing things that are not there.
  • Severe sleepiness, restlessness, or confusion.
  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, bladder problems or difficulty with urination, or epilepsy or seizures.
  • Check with your doctor right away if you get a urinary tract infection. This includes any infection in your bladder or kidneys. Your dose of this medicine might need to be changed while you have an infection.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Lightheadedness, dizziness, or fainting.
  • Seeing or hearing things that are not there.
  • Severe sleepiness, restlessness, or confusion.
  • Sudden or severe headache.
What is memantine used for?
Memantine is FDA-approved to treat moderate to severe dementia of the Alzheimer's type. It may help with memory, attention, reasoning, language, and the ability to perform daily activities, but it does not cure Alzheimer's or stop the disease from progressing.
How does memantine work for Alzheimer's disease?
Memantine is an NMDA receptor antagonist. In Alzheimer's disease, too much of a brain chemical called glutamate is thought to damage nerve cells. Memantine helps regulate glutamate activity in the brain, which may support memory and thinking. It manages symptoms rather than curing the disease.
What are the most common side effects of memantine?
The most common side effects are dizziness, headache, confusion, and constipation. Rare but serious effects can include hallucinations, seizures, and serious allergic reactions such as Stevens-Johnson syndrome. Contact your doctor if side effects concern you.
Is memantine the same as Namenda?
Yes. Memantine hydrochloride is the generic name for the brand-name drugs Namenda and Namenda XR. The generic contains the same active ingredient and is usually much less expensive than the brand-name versions.
Can memantine be taken with donepezil?
Yes. Memantine and donepezil work in different ways and are often prescribed together for Alzheimer's disease. They are also available as a single combination product called Namzaric. Always follow your doctor's instructions on how to take them.
How much does Memantine Hcl cost without insurance?
The price of Memantine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you. Many people save up to 89% off retail prices with a free Rx.com coupon.
What are the common side effects of Memantine Hcl?
Common side effects of Memantine Hcl may include: Sudden or severe headache., Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Change in how much or how often you urinate., Chest pain., Lightheadedness, dizziness, or fainting.. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Memantine Hcl?
Generic versions may be available for Memantine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Memantine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Memantine Hcl?
The cheapest pharmacy for Memantine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Memantine Hcl near you.

Memantine Hcl Coupons & Prices

Memantine

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Memantine Hcl Tablet — prescription drug image
Prescription
Memantine Hcl 10mg (60)
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Compounded GLP-1 medications are not FDA-approved and are prepared by state-licensed compounding pharmacies. They are not affiliated with, endorsed by, or equivalent to any brand-name medication or manufacturer. Prescription required; eligibility is determined by a licensed provider. Prices are estimates and may vary.

Memantine Hcl prices by dosage

Lowest cash price with a free Rx.com coupon vs. the average retail price.

Dosage Quantity Retail price Rx.com price
5mg · Tablet 60 $307.99 $14.99
10mg · Tablet 60 $150.09 $12.00

Cash prices near ZIP 77433; updated regularly. Actual pharmacy price may vary.

Looking for a memantine HCl coupon? Memantine hydrochloride is the low-cost generic version of Namenda and Namenda XR, prescribed to treat moderate to severe Alzheimer's-type dementia. Because it is available as a generic, memantine is already an affordable medication, but the cash price can still vary widely from one pharmacy to the next. Rx.com compares memantine prices across more than 60,000 pharmacies so you can find the best deal in your area. Enter your ZIP code above to see today's price near you.

What is memantine and how does it work?

Memantine hydrochloride is an NMDA receptor antagonist (a type of glutamate receptor antagonist). It is FDA-approved to treat moderate to severe dementia of the Alzheimer's type. In Alzheimer's disease, excess activity of a brain chemical called glutamate is thought to damage nerve cells. Memantine works by regulating this glutamate activity, which may help with memory, attention, reasoning, language, and the ability to carry out daily activities.

It is important to understand that memantine does not cure Alzheimer's disease and does not stop the disease from getting worse over time. It is often prescribed alongside a cholinesterase inhibitor such as donepezil (the two are also available together as the combination product Namzaric). Talk with your doctor about whether memantine is right for you.

How much does memantine cost without insurance?

Because memantine is available as a generic, it is typically one of the more affordable Alzheimer's medications, and you do not need insurance to use an Rx.com discount coupon. Even so, the cash price for the exact same prescription can differ significantly between pharmacies, which is why comparing prices matters. There is no manufacturer savings card for generic memantine.

Rx.com checks memantine prices at more than 60,000 pharmacies nationwide so you can compare and pick the lowest cash price near you. Enter your ZIP code above to see today's price and print or text yourself a free coupon.

Memantine vs. Namenda and other alternatives

Memantine is the generic name for the brand-name drugs Namenda (immediate-release) and Namenda XR (extended-release). The generic contains the same active ingredient and is usually much less expensive than the brand.

Because memantine works differently from cholinesterase inhibitors, doctors sometimes prescribe it together with drugs such as donepezil, rivastigmine, or galantamine. Memantine and donepezil are also combined in a single capsule sold as Namzaric. Your doctor can help you decide which option fits your treatment plan; you can compare prices for each of these on Rx.com.

Memantine safety and side effects

Memantine does not carry an FDA boxed warning and is not a controlled substance, with a low potential for abuse. The most common side effects are dizziness, headache, confusion, and constipation. Rare but serious effects can include hallucinations, seizures, and serious allergic reactions (including a severe skin reaction called Stevens-Johnson syndrome). If you notice a rash, blistering, or trouble breathing, seek medical care right away.

Memantine is cleared from the body mainly by the kidneys, so people with severe kidney impairment may need a lower dose. Certain conditions that make the urine more alkaline, such as renal tubular acidosis or severe urinary tract infections, can also raise memantine levels in the blood. This is general information, not medical advice. Tell your doctor about your kidney health and all medicines you take, and follow their guidance.

Sources & accuracy

This Memantine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Memantine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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