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Prescription NAD+ Therapy

NAD+ Injections Online: Cellular Energy Support, From Home

NAD+ is a coenzyme every cell uses to make energy and repair DNA, and your levels fall with age. Get at-home NAD+ injections through a confidential online visit with a U.S.-licensed provider, at a fraction of the cost of IV drips.

  • Used for energy, focus and recovery goals
  • A few minutes at home, not hours in an IV chair
  • Compounded by a licensed U.S. pharmacy
  • 100% online visit, plans never auto-renew
See If You Qualify From $99/month · free shipping
Rx.com NAD+ injectable vial

Compounded NAD+

Rx.com NAD+ Injection

100 mg/mL (10 mL vial)

from $99 /month

3-month plan, $297 upfront. Single month $179.

Start Your Online Visit About 1 minute. Plans don't auto-renew.

What is NAD+?

The coenzyme behind cellular energy

NAD+ (nicotinamide adenine dinucleotide) is found in every cell in your body. Your mitochondria need it to turn food into ATP, the energy cells run on, and it fuels enzymes such as sirtuins and PARPs that help repair DNA and respond to stress.

NAD+ levels decline as we age, and researchers are studying whether restoring them supports energy, metabolism and healthy aging. Injections deliver NAD+ directly, rather than relying on the body to build it from oral precursors like NMN or NR. The science is promising but early, and NAD+ is not approved to treat any condition. A provider reviews your health history and goals to decide whether it makes sense for you.

What people use NAD+ for

These are the goals people most often bring to their provider. Research in people is early and individual results vary.

Man in his 40s walking briskly with a coffee on a sunny morningEnergy

Steadier energy

NAD+ is central to how cells make energy, so many people try it for day-to-day energy and stamina.

Woman working focused at a bright home office deskFocus

Mental clarity

People often use NAD+ alongside good sleep and exercise to support focus and a clearer head.

Man in his 50s stretching after a home workoutRecovery

Recovery

NAD+ supports the cell processes behind repair, so some people use it around training and recovery.

Woman waking up rested in a bright bedroomSleep

Sleep and rhythm

NAD+ is tied to the body clock and cell metabolism; some people report waking up more refreshed.

Fit couple in their late 50s hiking a forest trailHealthy aging

Healthy aging

NAD+ levels fall with age, which is why it is one of the most studied molecules in healthy-aging research.

Two friends in their 40s laughing over brunchMood

Feeling like yourself

Energy and mood go together. Many people simply want to feel more like themselves again.

NAD+ injections vs. IV drips vs. supplements

All three are ways people try to raise NAD+. They differ a lot on cost, time and oversight.

Rx.com injectionIV dripNMN / NR
CostFrom $99/monthOften hundreds per sessionUsually the cheapest
TimeA few minutes at home2 to 4 hours in a chairSeconds a day
What you takeNAD+ itselfNAD+ itselfPrecursors your body converts
OversightU.S.-licensed provider and pharmacyVaries by clinicSold as supplements, no prescription

There is no good head-to-head evidence that one route works better than another. Supplements are a reasonable, lower-cost place to start; ask your provider what fits your goals.

See If NAD+ Is Right for You A licensed provider decides whether it is a fit.

What the research says

Here is what researchers have actually looked at, in plain English. Most of it used oral precursors or IV NAD+, not at-home injections, and none of it shows NAD+ treats or prevents a disease.

  • Human tissue study

    NAD+ levels in human tissue were lower in older adults than in younger adults.

    Massudi et al., PLoS One, 2012
  • Pilot IV study

    Researchers tracked how NAD+ and related compounds in blood and urine changed during a 6-hour NAD+ infusion in healthy men.

    Grant et al., Frontiers in Aging Neuroscience, 2019
  • Randomized trial

    Daily nicotinamide riboside, an NAD+ precursor, was well tolerated and raised NAD+ levels in healthy middle-aged and older adults.

    Martens et al., Nature Communications, 2018
Bright bathroom counter in the morning with a small medicine vial and a glass of water A few minutes, on your schedule

A simple at-home routine

NAD+ is a small subcutaneous injection, the same kind of short, thin needle used for insulin, usually into the fatty tissue of the belly or thigh. Your provider sets your dose and how often you inject, often several days a week.

Many people start at a lower dose and build up, which helps limit flushing. NAD+ is not a substitute for the basics: sleep, exercise and diet still do most of the work.

Tips people find helpful

  1. Inject slowly. Warmth or flushing is common and usually passes in minutes.
  2. Let the vial reach room temperature and stay hydrated, which can make it more comfortable.
  3. Rotate sites between belly and thigh to keep the skin comfortable.

Simple, upfront pricing

Compounded NAD+, 100 mg/mL (10 mL vial). Choose 3 months at $99 a month, paid upfront, or a single month at $179. Plans never auto-renew.

Rx.com compounded NAD+ injectable vial, 100 mg/mL
Best value

3 months

$99/month

Total $297 upfront

·

1 month

$179/month

Billed once

  • Provider review of your health intake
  • Personalized dosing
  • Compounded in the USA
  • Free shipping
  • No membership fee
  • Never auto-renews
Get Started About $3.30 a day on the 3-month plan. Prefer no needles? See NAD+ nasal spray

How it works

Licensed provider smiling during a video consultation U.S.-licensed providers
1

Online health intake

A confidential questionnaire about your health, goals and medications. No appointment, no waiting room.

2

Provider review

A U.S.-licensed provider reviews your answers and prescribes NAD+ only if it is right for you.

3

Delivered to your door

Your prescription is compounded by a licensed U.S. pharmacy and shipped free.

Start Your Online Visit

Important safety information

NAD+ injectable is a compounded medication. Compounded medications are not FDA-approved, and the FDA has not reviewed them for safety, effectiveness or quality. NAD+ is not approved to diagnose, treat, cure or prevent any disease, and statements on this page have not been evaluated by the FDA.

Common side effects include injection-site soreness or redness, flushing, headache and lightheadedness; nausea, fatigue, sleep changes or jitteriness are less common. NAD+ is not offered to people with a history of cancer, or during pregnancy or breastfeeding. Share your full health history and medication list during the intake. Get emergency care for trouble breathing or swelling of the face, tongue or throat.

NAD+ injection FAQs

What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell. It helps turn food into usable energy in the mitochondria and is used by enzymes involved in DNA repair, including sirtuins and PARPs. NAD+ levels tend to fall with age, which is why it is studied in healthy-aging research.
What are NAD+ injections used for?
People most often use NAD+ injections for energy, mental clarity and healthy-aging goals. Research on NAD+ is promising but still early: most human studies are small, and injectable NAD+ has not been proven to treat or prevent any disease. A provider will talk through what you can realistically expect.
Is NAD+ injectable FDA-approved?
No. NAD+ injectable is a compounded medication prepared by a licensed U.S. pharmacy for an individual prescription. Compounded medications are not FDA-approved, which means the FDA has not reviewed them for safety, effectiveness or quality.
How is it taken?
NAD+ is injected at home with a small needle, usually under the skin (subcutaneous). Your provider sets the dose and schedule, which is often several times a week, and your prescription comes with instructions. Starting low helps limit flushing and other side effects.
What side effects can NAD+ cause?
The most common are soreness, redness or a stinging feeling at the injection site, a warm flushing sensation, headache and lightheadedness. Less often people notice nausea, stomach upset, tiredness, trouble sleeping or feeling jittery in the first few doses. These are usually mild and often ease as your body adjusts or with a lower dose.
How soon will I notice anything?
It varies. Some people say they feel more energetic or clear-headed within the first few days, and others notice little change. Because the research is limited, there is no guaranteed timeline or result. Tell your provider how you feel so they can adjust your plan.
NAD+ injections vs. NMN or NR supplements?
NMN and NR are over-the-counter precursors your body converts into NAD+. Injections deliver NAD+ itself and skip the digestive system. Supplements are cheaper and need no prescription; injections are prescription-only. There is no good head-to-head evidence that one produces better results, so it is reasonable to ask your provider whether a supplement is enough for your goals.
Who should not use NAD+ injections?
NAD+ is not offered through Rx.com to people with a history of cancer, and it is not recommended during pregnancy or breastfeeding because it has not been studied there. Tell your provider if you have heart disease, liver or kidney disease, or take other medications, so they can decide whether it is appropriate for you.
Do I need a prescription?
Yes. You complete an online health questionnaire, a U.S.-licensed provider reviews it, and if treatment is appropriate a licensed U.S. pharmacy fills your prescription and ships it to you.
Does insurance cover it?
No insurance is needed. NAD+ is cash pay with upfront pricing: from $99 a month on a prepaid 3 month plan, or $179 for a single month. Plans do not auto-renew. Most insurance plans do not cover compounded NAD+. You may be able to use an HSA or FSA card; check with your plan administrator.

NAD+ Articles & Guides

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Browse all guides →

Ready to see if NAD+ is right for you?

Complete a short online intake and a U.S.-licensed provider will decide whether NAD+ injections fit your health history and goals.

Start Your Online Visit From $99/month · no membership fee · never auto-renews

Compounded medication: NAD+ is available only with a prescription from a licensed provider after a health evaluation. Compounded medications are prepared by a licensed compounding pharmacy and are not FDA-approved products; the FDA has not evaluated them for safety, effectiveness or quality. NAD+ is not intended to diagnose, treat, cure or prevent any disease. Individual results vary.

Research: Studies cited above are summarized for general information; they examined NAD+ biology, IV NAD+ or oral NAD+ precursors and do not show that Rx.com's NAD+ injection produces any specific result.

Medical services: All medical services, including clinical evaluations, treatment planning and prescribing decisions, are provided exclusively by licensed independent medical providers. Rx.com provides the technology platform and administrative coordination services, does not employ healthcare providers, and does not practice medicine. Rx.com does not manufacture compounded medications. This page is for informational purposes and is not a substitute for professional medical advice.

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