What is Savella Titration Pack ?

The Savella Titration Pack is a medication regimen designed to treat fibromyalgia by gradually increasing doses to improve tolerability. This pack contains varying doses of milnacipran hydrochloride, which functions as a selective serotonin and norepinephrine reuptake inhibitor (SNRI), aimed at alleviating pain and enhancing overall function in patients. The structured increase in dosage helps patients adapt to the medication while monitoring side effects and efficacy.

• Unusual bleeding or bruising
• Seizures or tremors
• Fast, pounding, or uneven heartbeat or pulse
• Thoughts of hurting yourself or others, unusual mood or behavior
• Increased energy, racing thoughts, reckless behavior, talking more than usual, trouble sleeping
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Anxiety, restlessness, fever, sweating, muscle spasms, diarrhea, seeing or hearing things that are not there
• Blistering, peeling, red skin rash
• Confusion, weakness, and muscle twitching
• Loss in sexual ability, desire, drive, or performance, delayed or inability to have an orgasm, inability to have or keep an erection
• Eye pain, vision changes, seeing halos around lights

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, heart rhythm problems, high blood pressure, glaucoma, an enlarged prostate, or a history of painful or difficult urination. Tell your doctor if you have a history of seizures or if you drink alcohol.
• For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
• This medicine may cause the following problems:Serotonin syndrome (may be life-threatening when used with certain other medicines)High blood pressureLiver problemsIncreased risk of bleeding problems (especially if used with a blood thinner or NSAIDs)Sexual problems
• This medicine may make you drowsy or less alert. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
• Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Your blood pressure and heart rate will also be monitored while you use this medicine.
• Keep all medicine out of the reach of children. Never share your medicine with anyone.
• Increased energy, racing thoughts, reckless behavior, talking more than usual
• Seizures or tremors
• Unusual behavior or thoughts about hurting yourself or others
• Unusual bleeding or bruising