Venlafaxine Hcl Er
Venlafaxine HCl ER 150MG
What is Venlafaxine Hcl Er?
Effexor XR is an antidepressant used to treat anxiety, depression, social phobia, and panic attacks. Venlafaxine is the generic version of Effexor XR. On average Effexor XR is priced at about $544 for a supply of 30, 150 mg capsules, extended-release. You can use our Rx.com savings offer to get an average Effexor XR discount of up to 80% off of the retail price at participating pharmacies near you.Side Effects
- Unusual behavior, thoughts of hurting yourself or others, trouble sleeping, nervousness, unusual dreams
- Feeling more excited or energetic than usual
- Seizures
Warnings
- This medicine may cause the following problems: Serotonin syndrome (may be life-threatening when used with certain other medicines)Increased cholesterol levelsIncreased blood pressureIncreased risk of bleeding problemsLung problems, including interstitial lung disease and eosinophilic pneumoniaSexual problems
- For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, glaucoma, heart disease, high blood pressure, or thyroid problems. Tell your doctor if you have a history of mania, seizures, heart attack, or stroke.
- This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely. This will help decrease the risk of unwanted effects.
Prescription savings · · · ·
What is Venlafaxine Hcl Er ?
Effexor XR is an antidepressant used to treat anxiety, depression, social phobia, and panic attacks. Venlafaxine is the generic version of Effexor XR. On average Effexor XR is priced at about $544 for a supply of 30, 150 mg capsules, extended-release. You can use our Rx.com savings offer to get an average Effexor XR discount of up to 80% off of the retail price at participating pharmacies near you.- Unusual behavior, thoughts of hurting yourself or others, trouble sleeping, nervousness, unusual dreams
- Feeling more excited or energetic than usual
- Seizures
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Anxiety, restlessness, fever, sweating, muscle spasms, nausea, vomiting, diarrhea, seeing or hearing things that are not there
- Blistering, peeling, red skin rash
- Chest pain, cough, trouble breathing
- Confusion, tiredness, weakness, and muscle twitching
- Fast or pounding heartbeat
- Loss in sexual ability, desire, drive, or performance, delayed or inability to have an orgasm, inability to have or keep an erection
- Unusual bleeding or bruising
- Eye pain, vision changes, seeing halos around lights
- Headache, dizziness, trouble concentrating, memory problems, unsteadiness
- This medicine may cause the following problems: Serotonin syndrome (may be life-threatening when used with certain other medicines)Increased cholesterol levelsIncreased blood pressureIncreased risk of bleeding problemsLung problems, including interstitial lung disease and eosinophilic pneumoniaSexual problems
- For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, glaucoma, heart disease, high blood pressure, or thyroid problems. Tell your doctor if you have a history of mania, seizures, heart attack, or stroke.
- This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely. This will help decrease the risk of unwanted effects.
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
- Headache, trouble concentrating, memory problems, unsteadiness
- Seizures
- Trouble sleeping, nervousness, unusual dreams
- Unusual behavior, thoughts of hurting yourself or others
- Unusual bleeding or bruising
Venlafaxine Hcl Er Coupons & Prices
Venlafaxine HCl ER 150MG
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Looking for a venlafaxine HCl ER coupon? Venlafaxine hydrochloride extended-release is the generic version of Effexor XR, an SNRI antidepressant. Because it is already available as a low-cost generic, the cash price is often modest, but it can still vary widely from one pharmacy to the next, which is why comparing matters. Rx.com compares prices across more than 60,000 pharmacies so you can find today's lowest price near you. Enter your ZIP above to see today's price.
What is venlafaxine HCl ER and how does it work?
Venlafaxine hydrochloride extended-release (the generic form of Effexor XR) is a serotonin-norepinephrine reuptake inhibitor, or SNRI. It works by increasing the levels of two brain chemicals, serotonin and norepinephrine, that help regulate mood and anxiety. The extended-release version is designed to release the medicine slowly over the day, so it is usually taken once daily.
Venlafaxine ER is FDA-approved to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder. Your prescriber decides whether it is the right choice for you.
Cost of venlafaxine HCl ER without insurance
Venlafaxine ER is a generic medication, so it is generally one of the more affordable options in its class. Even so, the cash price without insurance is not the same everywhere. Two pharmacies on the same street can list very different prices for the exact same prescription, so it pays to compare before you fill.
Rx.com checks prices across more than 60,000 pharmacies and shows you a free coupon for the lowest one near you. Enter your ZIP above to see today's price. If you prefer the brand-name version, the manufacturer of Effexor XR also offers a savings card at effexorxr.com; terms and eligibility vary, so check the official page for details.
Venlafaxine ER vs. related antidepressants
Venlafaxine ER is the generic equivalent of Effexor XR. If your prescriber is considering other options, several related medicines are commonly used for depression and anxiety:
- Desvenlafaxine — a closely related SNRI (the active metabolite of venlafaxine).
- Duloxetine — another SNRI.
- Sertraline and Escitalopram — SSRIs, a different but related class.
Only your healthcare provider can decide which medicine fits your situation. You can compare cash prices for each of these on Rx.com.
Safety and things to know
This is general information, not medical advice; always follow your provider's guidance. Venlafaxine ER carries a boxed warning for an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults under 24, especially early in treatment or after a dose change. It can raise blood pressure and heart rate in a dose-related way, and there is a risk of serotonin syndrome, particularly when combined with MAOIs (which are contraindicated) or other serotonergic drugs.
Other possible effects include low sodium (hyponatremia), a higher chance of abnormal bleeding when taken with NSAIDs, aspirin, or blood thinners, and angle-closure glaucoma. Do not stop venlafaxine ER suddenly. Stopping abruptly can cause a discontinuation syndrome with dizziness, nausea, irritability, and electric-shock sensations, so your provider will usually have you taper the dose gradually. Talk to your doctor or pharmacist about your full medication list and any concerns.
This Venlafaxine Hcl Er information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Venlafaxine Hcl Er on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.