Bupropion Hcl Er (Xl) Coupons & Prices

Looking for a bupropion HCl ER XL coupon? Bupropion hydrochloride extended-release (XL) is the low-cost generic version of Wellbutrin XL, an antidepressant used to treat major depressive disorder and to prevent seasonal depression. Because it is already available as a generic, cash prices are often modest, but they can vary widely from one pharmacy to the next, so comparing matters. Enter your ZIP above to see today's price at pharmacies near you. Rx.com compares prices across more than 60,000 pharmacies to help you find the lowest one, no insurance required.

What is bupropion HCl ER XL and how does it work?

Bupropion hydrochloride extended-release (XL) is an aminoketone antidepressant classified as a norepinephrine-dopamine reuptake inhibitor (NDRI). It works differently from many common antidepressants, raising the activity of the brain chemicals norepinephrine and dopamine. The extended-release XL formulation is taken once daily.

Bupropion XL is FDA-approved to treat major depressive disorder (MDD) and, in the XL formulation specifically, to prevent seasonal affective disorder (seasonal MDD). It is sold under the brand name Wellbutrin XL and, at a higher single-tablet strength, as Forfivo XL. A related medicine, Aplenzin, uses a different salt (bupropion hydrobromide). This information is educational and not a substitute for advice from your doctor or pharmacist.

How much does bupropion HCl ER XL cost without insurance?

Bupropion HCl ER XL is available as a generic, so it is usually one of the more affordable antidepressant options, even for people paying cash without insurance. That said, the price is not the same everywhere. The cash price for the very same prescription can differ significantly between two pharmacies in the same town, which is exactly why comparing before you fill is worth it.

To see what bupropion XL costs today at pharmacies near you, enter your ZIP code above. Rx.com checks prices across more than 60,000 pharmacies and shows you a coupon you can use at the counter. If you have been prescribed the brand-name Wellbutrin XL, a manufacturer savings program is offered at the official Wellbutrin XL savings page; eligibility and terms vary, so check the manufacturer's site for details.

Bupropion XL alternatives and related medications

Bupropion comes in more than one release form, and there are other antidepressants your prescriber may consider. Related options include:

• Wellbutrin XL — the brand-name equivalent of bupropion HCl ER XL
• Bupropion HCl ER (SR) — the sustained-release form, usually taken twice daily
• Bupropion HCl — the immediate-release form
• Zyban — a bupropion SR product approved for smoking cessation
• Aplenzin — bupropion hydrobromide, another once-daily brand
• Sertraline, escitalopram, and venlafaxine — other antidepressants in different drug classes

Only your prescriber can decide which medication and formulation is right for you. Whichever one you are prescribed, you can compare its cash price on Rx.com.

Important safety information

Bupropion HCl ER XL carries a boxed warning for an increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults under 25, especially when starting treatment or changing the dose; close monitoring is advised. The medicine also carries a dose-related risk of seizures. It should not be used by people with a seizure disorder, a current or prior diagnosis of bulimia or anorexia nervosa, or those abruptly stopping alcohol, benzodiazepines, barbiturates, or antiseizure drugs. It is contraindicated with MAO inhibitors, and at least 14 days should pass between the two.

Bupropion can also cause high blood pressure, insomnia, agitation or anxiety, mania in people with bipolar disorder, psychosis or hallucinations, and angle-closure glaucoma. Do not take more than one bupropion product at the same time. This is not medical advice — talk with your doctor or pharmacist about your health history and any other medicines you take before starting or stopping bupropion.