Clomipramine Hcl
clomiPRAMINE HCl 50MG
What is Clomipramine Hcl?
Clomipramine is a medication used to treat obsessive-compulsive disorder (OCD), which involves repeated unwanted thoughts and behaviors. It belongs to a group of drugs known as tricyclic antidepressants and helps improve mental balance.Side Effects
- Feeling more excited or energetic than usual, racing thoughts, trouble sleeping
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Agitation, confusion, depression, irritability, memory problems
Warnings
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, an adrenal gland tumor (including neuroblastoma), glaucoma, depression, mood or mental problems (including bipolar disorder, schizophrenia, mania), thyroid problems, trouble urinating, or a history of seizures or brain damage. Tell your doctor if you drink alcohol.
- This medicine may cause the following problems:Serotonin syndrome (may be life-threatening when used with certain other medicines)Increased risk of seizuresDrug reaction with eosinophilia and systemic symptoms (DRESS), which can damage organs, including the liver, kidney, or heartLiver problemsProblems with sex (in males)
- For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- This medicine may make it more difficult for your body to cool itself down. Use care not to become overheated during exercise or hot weather since overheating may result in heat stroke.
Prescription savings · · · ·
What is Clomipramine Hcl ?
Clomipramine is a medication used to treat obsessive-compulsive disorder (OCD), which involves repeated unwanted thoughts and behaviors. It belongs to a group of drugs known as tricyclic antidepressants and helps improve mental balance.- Feeling more excited or energetic than usual, racing thoughts, trouble sleeping
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Agitation, confusion, depression, irritability, memory problems
- Anxiety, restlessness, fever, sweating, muscle spasms, nausea, vomiting, diarrhea, seeing or hearing things that are not there
- Chest pain, fast or pounding heartbeat
- Confusion, weakness, muscle twitching
- Dark urine, pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Fast breathing, pale, clammy skin, high fever or body temperature, increased thirst
- Seizures or tremors
- Swollen, painful, or tender lymph glands in the neck, armpit, or groin
- Thoughts of hurting others or yourself, unusual behavior
- Unusual bleeding, bruising, or weakness
- Lightheadedness, dizziness, fainting
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, an adrenal gland tumor (including neuroblastoma), glaucoma, depression, mood or mental problems (including bipolar disorder, schizophrenia, mania), thyroid problems, trouble urinating, or a history of seizures or brain damage. Tell your doctor if you drink alcohol.
- This medicine may cause the following problems:Serotonin syndrome (may be life-threatening when used with certain other medicines)Increased risk of seizuresDrug reaction with eosinophilia and systemic symptoms (DRESS), which can damage organs, including the liver, kidney, or heartLiver problemsProblems with sex (in males)
- For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.
- This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
- This medicine may make it more difficult for your body to cool itself down. Use care not to become overheated during exercise or hot weather since overheating may result in heat stroke.
- This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
- Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
- Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Clomipramine Hcl Coupons & Prices
clomiPRAMINE HCl 50MG
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Looking for a clomipramine HCl coupon? Clomipramine hydrochloride is the generic form of Anafranil, a tricyclic antidepressant FDA-approved to treat obsessive-compulsive disorder (OCD). As a generic, it is already one of the lower-cost options in its class, but the cash price can vary widely from one pharmacy to the next, so comparing before you fill genuinely matters. Rx.com checks prices across more than 60,000 U.S. pharmacies so you can find a lower price near you. Enter your ZIP above to see today's price and print or text yourself a free coupon.
What is clomipramine and how does it work?
Clomipramine hydrochloride (brand name Anafranil) is a tricyclic antidepressant, or TCA. It is FDA-approved to treat obsessive-compulsive disorder (OCD) in adults and in children age 10 and older, when obsessions or compulsions cause marked distress, take up a lot of time, or significantly interfere with daily life. It works by affecting the balance of natural chemicals in the brain, including serotonin, that influence mood and behavior.
Clomipramine is taken by mouth, usually once daily or in divided doses, and your prescriber will typically start low and adjust the dose over time. It is also used by some clinicians for other conditions; those uses are decisions for you and your doctor to make together. This page is general information, not medical advice.
Clomipramine cost and how to save without insurance
Because clomipramine is available as an FDA-approved generic, it is generally far less expensive than brand-name Anafranil and is one of the more affordable medicines in its class. That does not mean every pharmacy charges the same, though. Cash prices for the same strength and quantity can differ substantially between a chain drugstore, a grocery pharmacy, and an independent pharmacy across town.
There is no manufacturer copay savings card for clomipramine. Instead, a free Rx.com discount coupon can lower the cash price whether or not you use insurance, and you never enter a dollar amount to use it. Enter your ZIP above to see today's price at pharmacies near you, then bring the coupon to the counter. It costs nothing to compare.
Clomipramine vs. other OCD and TCA options
Clomipramine is often compared with SSRIs, which are also commonly used for OCD and generally have a lighter side-effect profile. If you and your prescriber are weighing choices, related medicines include fluvoxamine, sertraline, and fluoxetine.
Within the tricyclic family, close relatives include imipramine, amitriptyline, and nortriptyline. These are not interchangeable, and only your prescriber can decide which drug and dose fit your situation. Whatever you are prescribed, you can compare its cash price on Rx.com before you fill.
Important safety information
Clomipramine carries a boxed warning for an increased risk of suicidal thoughts and behavior in children, adolescents, and young adults, especially when starting the medicine or changing the dose; close monitoring is important. It is not approved for children under 10. Clomipramine should not be taken with MAO inhibitors because of the risk of serotonin syndrome and dangerous spikes in blood pressure, and it should not be started during the acute recovery period after a heart attack.
Common side effects include dry mouth, constipation, blurred vision, urinary retention, drowsiness, weight gain, sexual difficulties, and dizziness when standing up. Clomipramine can lower the seizure threshold and affect heart rhythm, so tell your prescriber about any seizure history or heart condition. Do not stop taking it suddenly, and talk with your doctor or pharmacist about any other medicines you take. This is general information and not a substitute for your provider's advice.
This Clomipramine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.
Verify the official label: Clomipramine Hcl on DailyMed (FDA)
Reviewed against FDA labeling · Last reviewed July 2026
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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.