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Clonidine Hcl Tablet — prescription drug image

Clonidine Hcl

cloNIDine HCl 0.1MG

Prescriptions & Refills
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What is Clonidine Hcl?

Catapres is used to treat high blood pressure and ADHD. Clonidine is the generic version of Catapres. You can use our Singlecare savings offer to get an average Catapres discount of up to 80% off of the average cost at participating local pharmacies.

Prescription savings · · · ·

What is Clonidine Hcl ?

Catapres is used to treat high blood pressure and ADHD. Clonidine is the generic version of Catapres. You can use our Singlecare savings offer to get an average Catapres discount of up to 80% off of the average cost at participating local pharmacies.
  • Unusual tiredness or weakness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fast, slow, pounding, or uneven heartbeat
  • Lightheadedness, dizziness, fainting
  • Swelling in your hands, ankles, or feet
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Even if you feel well, do not stop using the medicine without asking your doctor first. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.
  • Tell your doctor if you are pregnant, breastfeeding, or have kidney disease, heart or blood vessel disease, heart rhythm problems, stomach or bowel problems, or a history of heart attack or stroke.
  • This medicine may make you drowsy, dizzy, or lightheaded. Do not drive or do anything that could be dangerous until you know how this medicine affects you.
  • This medicine may cause dryness of the eyes. Talk to your doctor about how to treat the dryness.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.
What is clonidine HCl used for?
Clonidine HCl is FDA-approved to treat high blood pressure (hypertension) as immediate-release tablets, a skin patch, and an extended-release tablet. Certain extended-release forms (Kapvay, Onyda XR) are approved for ADHD in children ages 6 to 17, and an epidural injection is approved for severe cancer pain. It is also frequently prescribed off-label for other conditions under a provider's direction.
Is clonidine a controlled substance?
No. Clonidine is not a federally controlled substance and has no DEA schedule. It is a prescription medicine, so you still need a valid prescription from a licensed provider to fill it.
What happens if you stop taking clonidine suddenly?
Stopping clonidine abruptly can cause rebound hypertension, meaning a sharp rise in blood pressure, sometimes with agitation, headache, and tremor. Because of this, clonidine should be tapered slowly rather than stopped all at once. Do not stop on your own; talk with your prescriber about how to reduce the dose safely.
Can clonidine be used for anxiety and sleep?
Clonidine is FDA-approved for high blood pressure and, in specific extended-release forms, for pediatric ADHD. It is sometimes prescribed off-label for anxiety or sleep, but that use is at a provider's discretion and is not an approved indication. Discuss the risks and benefits with your doctor rather than using it this way on your own.
What is the difference between clonidine and Kapvay?
Kapvay is a brand name for an extended-release form of clonidine that is FDA-approved for ADHD in children ages 6 to 17. Standard clonidine is usually the immediate-release tablet approved for high blood pressure. The two are not interchangeable milligram-for-milligram, so they cannot be swapped without your prescriber adjusting the dose.
How much does Clonidine Hcl cost without insurance?
The price of Clonidine Hcl without insurance varies by pharmacy, dosage, and quantity. Rx.com compares cash prices at more than 60,000 US pharmacies so you can find the lowest price near you.
What are the common side effects of Clonidine Hcl?
Common side effects of Clonidine Hcl may include: Unusual tiredness or weakness, Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing, Fast, slow, pounding, or uneven heartbeat, Lightheadedness, dizziness, fainting, Swelling in your hands, ankles, or feet. This is not a complete list — consult your pharmacist or doctor for full side effect information.
Is there a generic version of Clonidine Hcl?
Generic versions may be available for Clonidine Hcl. Generics contain the same active ingredients as brand-name drugs and are typically 80–90% cheaper. Search Clonidine Hcl on Rx.com to compare generic and brand prices at pharmacies near you.
What is the cheapest pharmacy for Clonidine Hcl?
The cheapest pharmacy for Clonidine Hcl depends on your location and dosage. Rx.com compares prices at CVS, Walgreens, Walmart, Kroger, Costco, and thousands of independent pharmacies. Enter your ZIP code on Rx.com to find the lowest price for Clonidine Hcl near you.

Clonidine Hcl Coupons & Prices

cloNIDine HCl 0.1MG

Prescriptions & Refills
Licensed US providers · Online visit in minutes
Clonidine Hcl Tablet — prescription drug image
Prescription
Clonidine Hcl 0.1mg (30)
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Looking for a clonidine HCl coupon? Clonidine hydrochloride is a long-established generic medicine, so it is already one of the more affordable options in its class, but the cash price can still swing a surprising amount from one pharmacy to the next. Rx.com compares clonidine prices across more than 60,000 pharmacies so you can pull up today's discounted price near you and bring a free coupon to the counter. Enter your ZIP above to see today's price on clonidine HCl in your area.

What is clonidine HCl and how does it work?

Clonidine hydrochloride is a centrally acting alpha-2 adrenergic agonist. It works in the brain to reduce the nerve signals that raise blood pressure, which relaxes blood vessels and slows the heart rate. The FDA has approved it to treat hypertension (high blood pressure) in several forms: immediate-release tablets (brand name Catapres), a transdermal patch (Catapres-TTS), and an extended-release tablet (Jenloga). Extended-release formulations sold as Kapvay and Onyda XR are FDA-approved to treat ADHD in children ages 6 to 17, either on their own or added to a stimulant. An epidural injection (Duraclon) is approved for severe cancer pain.

Clonidine is also very commonly prescribed off-label for other conditions. Because uses and dosing differ a great deal between formulations, always follow the exact product and instructions your prescriber chose for you.

How much does clonidine HCl cost without insurance?

Clonidine HCl is available as an FDA-approved generic, which is why it is generally inexpensive compared with brand-name blood pressure and ADHD medicines. That said, the cash price without insurance is not the same everywhere. Two pharmacies on the same street can list very different prices for the identical tablet, so it genuinely pays to compare before you fill.

Rx.com checks clonidine pricing across more than 60,000 U.S. pharmacies and shows you a free discount coupon you can use whether or not you have insurance. There is no membership fee. Enter your ZIP above to see today's price and print or text yourself the coupon before you go.

Clonidine alternatives and related medicines

If you and your provider are weighing options, several related medicines may come up depending on what you are treating:

  • Guanfacine - another alpha-2 agonist used for high blood pressure and, in an extended-release form, for ADHD in children.
  • Catapres - the brand-name immediate-release clonidine tablet.
  • Kapvay - an extended-release clonidine approved for pediatric ADHD.
  • Methyldopa - a centrally acting blood pressure medicine often used in pregnancy.
  • Tizanidine - a related alpha-2 agonist used as a muscle relaxant.

These medicines are not interchangeable, and switching should only happen under your prescriber's guidance. You can compare cash prices on any of them through Rx.com.

Important safety information

Do not stop clonidine suddenly. Abrupt discontinuation can cause rebound high blood pressure along with agitation, headache, and tremor. If you and your provider decide to stop, the dose is tapered gradually (generally no more than 0.1 mg every 3 to 7 days). Clonidine commonly causes drowsiness, sedation, dizziness, and dry mouth, so avoid driving until you know how it affects you, and use caution with alcohol or other medicines that slow the nervous system. It can also slow the heart rate (bradycardia) and lower blood pressure, so extra care is needed for anyone with a heart conduction disorder, a history of fainting, or cardiovascular disease.

Keep in mind that the extended-release forms (Kapvay, Onyda XR) are not interchangeable milligram-for-milligram with immediate-release clonidine, and doses above 0.4 mg per day have not been studied for ADHD. This is general information, not medical advice. Talk with your doctor or pharmacist about your specific situation and any other medicines you take.

Sources & accuracy

This Clonidine Hcl information was written and reviewed against authoritative U.S. medical sources — MedlinePlus (U.S. National Library of Medicine), DailyMed, and FDA prescribing information — and checked for accuracy. It is provided for education and is not a substitute for professional medical advice.

Verify the official label: Clonidine Hcl on DailyMed (FDA)

Reviewed against FDA labeling · Last reviewed July 2026

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Medical disclaimer: This information is provided for general educational purposes only and is not medical advice. It is not a substitute for professional diagnosis or treatment. Always consult a licensed physician, pharmacist, or other qualified healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you read here. If you think you may have a medical emergency, call your doctor or 911 immediately.


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