Drospiren-Eth Estrad-Levomefol Coupons & Prices

Searching for a drospirenone / ethinyl estradiol / levomefolate coupon? This is a combination birth control pill that pairs a progestin (drospirenone), an estrogen (ethinyl estradiol), and a folate (levomefolate calcium, the active form of folic acid). It comes in two distinct products that are not interchangeable: a lower-estrogen 24/4 version (ethinyl estradiol 0.02 mg), sold as the brand Beyaz with the generic Rajani; and a higher-estrogen 21/7 version (ethinyl estradiol 0.03 mg), sold as the brand Safyral with the generic Tydemy. Because a generic is already lower in cost than the brand, and cash prices can vary widely from one pharmacy to the next, comparing matters. An Rx.com cash coupon can help you pay less whether or not you have insurance. Enter your ZIP above to see today's price at pharmacies near you.

What is drospirenone / ethinyl estradiol / levomefolate and how does it work?

This medicine is a combination oral contraceptive that pairs the progestin drospirenone with the estrogen ethinyl estradiol, plus levomefolate calcium, the active form of folic acid. It is FDA-approved to prevent pregnancy. The folate component raises red-blood-cell and plasma folate levels, which helps lower the risk of a neural tube defect if a pregnancy occurs while taking the pill or shortly after stopping it.

The combination is sold in two different formulations that differ in estrogen dose, tablet schedule, and approved uses, so they are not simply interchangeable. The 24/4 version (ethinyl estradiol 0.02 mg), sold as Beyaz, is approved to prevent pregnancy, to treat premenstrual dysphoric disorder (PMDD) in women who choose oral contraception, and to treat moderate acne vulgaris in women at least 14 years old who have started menstruating and want contraception. The 21/7 version (ethinyl estradiol 0.03 mg), sold as Safyral, is approved for contraception plus folate supplementation only, not for PMDD or acne. This pill does not protect against HIV or other sexually transmitted infections. This page is educational and not a substitute for medical advice; talk with your provider about which version, if any, is right for you.

Cost without insurance: why comparing pharmacies matters

The biggest savings lever here is that a generic is available for each version. Rajani is the generic of the 24/4 Beyaz, and Tydemy is the generic of the 21/7 Safyral. Ask your pharmacist or provider whether the generic that matches your prescribed product is right for you, since generics typically cost far less than brand-name pricing. Even so, cash prices for the generic can vary widely from one pharmacy to another, so it pays to compare before you fill. Rx.com compares cash prices across more than 60,000 pharmacies so you can find a lower price near you.

An Rx.com cash coupon is a cash-price discount you can use even if you are uninsured, have Medicare or Medicaid, or if a manufacturer card is declined at the counter. You do not use it together with insurance, but you can compare the coupon price against your insurance copay and pick whichever is lower. The brand-name versions may offer a manufacturer savings card; such cards are generally limited to people with commercial (non-government) insurance and come with terms that vary, so search for the Beyaz or Safyral savings card on the manufacturer's official website for current details. Enter your ZIP above to see today's price at pharmacies near you.

Brand versions and related birth control options

The drospirenone / ethinyl estradiol / levomefolate combination is sold as two distinct brand-and-generic pairs that are not interchangeable with each other:

• 24/4 version, ethinyl estradiol 0.02 mg: brand Beyaz, with the substitutable generic Rajani. This version is also approved for PMDD and moderate acne.
• 21/7 version, ethinyl estradiol 0.03 mg: brand Safyral, with the substitutable generic Tydemy. This version is approved for contraception plus folate supplementation only.

Rajani and Tydemy are generics, not separate brands, and each is a generic of only its matching product. Because the two versions differ in estrogen dose and dosing schedule, they should not be treated as substitutes for one another; fill the specific product your provider prescribed. If cost is a concern, the generic is usually the most affordable way to get that same version.

Your provider may also discuss other drospirenone-containing pills that do not include folate, such as drospirenone and ethinyl estradiol and its brands Yaz and Yasmin. The right choice depends on your health history and whether you want the added folate, so let your provider guide the decision.

Safety and important warnings

This medicine carries a boxed warning: cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives, and women over 35 who smoke should not use it. Drospirenone-containing pills may carry a higher risk of blood clots (venous thromboembolism) than some other combined birth control pills. Drospirenone can also raise blood potassium levels, so it should be avoided or closely monitored in people with kidney, liver, or adrenal problems, or those taking other medicines that raise potassium, such as ACE inhibitors, ARBs, potassium-sparing diuretics, aldosterone antagonists, NSAIDs, or heparin.

It is not for everyone. It is contraindicated in women at high risk of arterial or venous blood clots, certain migraines, liver disease or liver tumors, undiagnosed abnormal uterine bleeding, breast or other estrogen- or progestin-sensitive cancers, and pregnancy. There is also an increased risk of stroke, heart attack, high blood pressure, and gallbladder disease. Seek emergency care for chest pain, shortness of breath, severe leg pain or swelling, a sudden severe headache, vision changes, or weakness or numbness in an arm or leg. This is general information, not medical advice. Review your full health history and all medicines you take with your provider before starting or continuing this pill.